New aspects in release of atrial natriuretic peptide. Role of calcium and parathyroid hormone.
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Biomedical subjects
Publications and source records attributed to M Meissner.
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Despite of the necessity of an increasing primary prevention the therapy of class V cavities will be of greater importance already in the next future. In this review of the literature the indications, advantages, disadvantages as well as the practical procedure for the therapy of cervical lesions with amalgam, metal inlays, composites, glass ionomer cements, porcelain restorations,a nd composite inlays are discussed.
The therapy of cervical lesions in the visible facial area is not free of problems. The aim of this study is to investigate the marginal leakage by means of SEM analysis after in vitro and in vivo application of porcelain inlays in the cervical area, bonded to the enamel by a microfilled composite. Our results show, that the bond between composite and enamel is better than the bond between composite and inlay treated with a silane coupling agent. Problems of the leakage size and of the transparency can favourably be influenced by the composite as cementation material.
Positron emission tomography with 11C-2-deoxyglucose was used to determine the test-retest variability of regional cerebral glucose metabolism in 22 young normal right-handed men scanned twice in a 24-h period under baseline (resting) conditions. To assess the effects of scan order and time of day on variability, 12 subjects were scanned in the morning and afternoon of the same day (a.m.-p.m.) and 10 in the reverse order (p.m.-a.m.) with a night in between. The effect of anxiety on metabolism was also assessed. Seventy-three percent of the total subject group showed changes in whole brain metabolism from the first to the second measurement of 10% or less, with comparable changes in various cortical and subcortical regions. When a scaling factor was used to equate the whole brain metabolism in the two scans for each individual, the resulting average regional changes for each group were no more than 1%. This suggests that the proportion of the whole brain metabolism utilized regionally is stable in a group of subjects over time. Both groups of subjects had lower morning than afternoon metabolism, but the differences were slight in the p.m.-a.m. group. One measure of anxiety (pulse at run 1) was correlated with run 1 metabolism and with the percentage of change from run 1 to run 2. No significant run 2 correlations were observed. This is the first study to measure test-retest variability in cerebral glucose metabolism in a large sample of young normal subjects. It demonstrates that the deoxyglucose method yields low intrasubject variability and high stability over a 24-h period.
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The two monoclonal antibodies HRS-1 and HRS-2, which were obtained after immunization with the Hodgkin's derived cell line L428, detect different epitopes on a 120 kd antigen. This antigen is present on Hodgkin- and Reed-Sternberg (H&RS) cells in all subtypes of Hodgkin's lymphoma and on large cell anaplastic non-Hodgkin's lymphomas. The H&RS- associated 120 kd antigen appears to be a non-lineage specific activation antigen, as it is not present on normal B and T lymphocytes or monocytes, but appears on these cells after activation. Because of their restricted reactivity with H&RS cells, HRS-1 and HRS-2 alone or in combination may be helpful for immunoimaging and immunotherapy of Hodgkin's lymphomas.