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Biomedical subjects

M Meradji

Publications and source records attributed to M Meradji.

At least 55 records · Page 3Linked to original sources
PubMed1982

Orthotopic nonauxiliary homotransplantation of part of the liver in dogs.

An experimental study was carried out investigating the feasibility of using only a portion of a donor liver in orthotopic, nonauxiliary transplantation, establishing a canine model. After being totally hepatectomized, 20 immunosuppressed adult beagles received a 60% donor liver graft, derived from tissue-typed identical littermates. Preservation time was 5 hr. In control experiments, 10 beagles, only half of them immunosuppressed, underwent an operation involving complete liver mobilization, vascular exclusion, cooling of the liver in situ, and a 40% partial hepatectomy with biliary anastomosis. The surgical procedure, including the method of cooling and preservation, is described in detail. Survival rate amounted to 90% for the control group and 50% for the transplanted group, while all surviving dogs were sacrificed 24 wk postoperatively. At sacrifice, the liver weight amounted to the weight of the total native liver at operation. Body weight profiles reflect good general condition of the surviving dogs. No major differences were noted between the immunosuppressed and the nonimmunosuppressed control dogs. No complications were related to the fact that only a partial liver was grafted or left in situ.

Animals↗
PubMed1980

Necrotising enterocolitis after cardiac catheterisation in infants.

Necrotising enterocolitis occurred in 3 infants after angiography at cardiac catheterisation. It is suggested that hypertonic contrast medium might have been responsible and that this complication could be avoided by the use of nonionic contrast media.

Cardiac Catheterization↗
PubMed1978

Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment.

Idiopathic infantile arterial calcification is a disorder of unknown etiology manifested by widespread arterial calcification. This usually leads to early death from coronary artery occlusion. In 12 of the 75 cases in the literature, radiographs were taken and it was possible to make the diagnosis in them all. We present two patients, siblings, in whom the diagnosis was established radiologically. The nature of the calcium deposits was studied in one of the infants and proved to be calcium hydroxyapatite. Therapy with diphosphonate was apparently successful in the other child.

Arteriosclerosis↗
PubMed1977

Treatment of intussusception in children operative treatment versus hydrostatic reduction.

Intestinal intussusception is a serious abdominal emergency in infancy and childhood, with a high mortality-rate if not diagnosed and treated early. Since the management of intussusception in children is still controversial, the pro's and con's for barium enema reduction and for surgical treatment are discussed. The results of our own series of 19 patients primarily treated by barium-enema reduction compare favourably with a previous series of 14 patients treated by primary surgery.

Barium Sulfate↗
PubMed1976

Contribution of fibreoptic endoscopy to diagnosis and management of children with gastro-oesophageal reflux.

Endoscopic and radiological examination was performed in 53 children with gastro-oesophageal reflux. There was fair agreement between endoscopic and radiological findings. Most patients showed either a normal or an erythematous oesophageal mucosa at endoscopy and these patients became asymptomatic on conservative therapy. 7 children presented destructive changes of the oesophageal mucosa with severe pathological abnormalities. Though their symptoms improved on conservative therapy, 5 required operation because of persistence or deterioration of mucosal damage. Endoscopic and pathological changes returned to normal after operation. Retrospective examination of data led to the definition of 'high risk factors' in this condition.

Biopsy↗
PubMedDate not supplied

Bronchial carcinoid tumor in a 12-year-old child.

Symptoms (hemoptysis, recurrent pulmonary infections), diagnostic work-up (roentgenology, bronchoscopy with biopsy), and treatment (surgical resection of a bronchial carcinoid tumor in a 12 year old girl) are discussed. Special attention was paid to the tumor histochemistry, showing serotonin containing granules. Levels of circulating hormones and vasoactive agents, including serotonin, were within normal limits.

Bronchial Neoplasms↗
PubMedDate not supplied

Pervenous hepatic transplant angiography using a new low osmolar contrast medium: an experimental study in dogs.

The patency of the vascular anastomoses in a canine liver transplantation model was imaged by serial pervenous angiography using ioxaglate, which is a new ionic low osmolar contrast medium. No premedication or general anesthesia was administered. No major adverse reaction was noted, not even after repeated angiography. Except for the occurrence of one hematoma formation and one paravenous injection, which resolved without leaving sequellae, no local complications occurred. Sufficient information regarding the patency of the hepatic artery anastomosis was obtained in 94% of the angiographic studies, while in 70% the patency of the caval anastomoses could be determined. In addition, portal vein patency was imaged in 21% of the angiograms. Even better visualization results can be expected when combining this method with video subtraction techniques, although patient cooperation or general anesthesia would then be mandatory.

Angiography↗