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M Mercadier

Publications and source records attributed to M Mercadier.

At least 37 records · Page 2Linked to original sources

Caroli's disease.

Explore the source record for details and available documents.

Adolescent↗

[Surgical treatment of Basedow's disease. Study of a homogenous series of 105 cases].

Basedow's disease was the indication for surgery in 105 of 3000 operations on the thyroid performed over the last 15 years. The choise of operative therapy was based on age of patient, size of thyroid, and the failure of medical treatment to provide more than partial improvement or to prevent recurrence. Pre-operative preparation must follow a strict procedure. Surgery was initially by bilateral subtotal lobectomy, soon modified to include a left total combined lobectomy with a right subtotal lobectomy (25 p. 100 of operations). Postoperative complications among the first patients treated, in 1966, included one death from an acute toxic reaction, three lesions of the recurrent nerves (only one was permanent) and four cases of hypothyroidism (three were transient). A one to 15 years follow up was possible in 80 p. 100 of the patients. Recurrence was noted in 9 cases, two of these developing after a long period (6 and 10 years respectively). These recurrences appear to be related the sex (males), age (under 40 years), weight of goitre (50 g and over), and the type of excision (bilateral subtotal as against unilateral total lobectomy). Of the 74 patients failing to develop a relapse, 80 p. 100 were normothyroidal and 20 p. 100 hypothyroidal, while 91 p. 100 were sujectively with the results of their operation.

Adolescent↗

[Vater's ampulla neoplasms. Diagnostic and therapeutic approach. Apropos of 18 cases].

Diagnostic and therapeutic aspects of neoplasms of the ampulla of Vater are discussed in relation to a relatively small but homogeneous series of 18 cases. The presenting sign is almost always jaundice, with or without associated manifestations of the angiocholitic type, sometimes regressive but recurrent. A rapid diagnosis should now be possible by ultrasound imaging of the dilated intra- and extra-hepatic biliary pathways, complemented by either fibroscopy with or without retrograde catheterization or trans-parieto-hepatic-cholangiography. The most effective therapy appears to be cephalic duodeno pancreatectomy, pathologic examination of fresh specimens of possible adenopathies being of doubtful interest since the presence of N + lymph nodes does not prevent prolonged life expectancy. The principal technical problem is related to the pancreatic stump, since this is formed of healthy parenchyma capable of provoking a fistula whether or not a pancreatico-digestive anastomosis has been performed. It might be possible in the future to use substances blocking the external secretion of the pancreatic stump left in place, in order to diminish the risk of fistula and its well-known consequences. Tumors of the ampulla of Vater have a relatively favorable prognosis when compared with that of other neoplasms in the biliopancreatic intersection zone, and an aggressive attitude to their therapy is therefore fully justified.

Adult↗

[Treatment of postero-superior amoebic abscess of the liver. A plea for a return to the thoracic approach with exclusion of the pleura (author's transl)].

Right anterolateral thoracotomy with exclusion of the pleura was successfully carried out in 14 cases of amoebic liver abscess. This approach is indicated for abscesses located on the posterior and superior surfaces of the liver. The operation is easy and rapidly executed. Selective drainage can be installed without any risk of pleural or peritoneal contamination, and the post-operative period is smooth.

Humans↗

[A case of papillary disinsertion during gastro-duo-denectomy for ulcer of the second part of the duodenum and its repair by a "physiological" reconstruction (author's transl)].

The authors report a personal case of repair of papillary disinsertion. They emphasise the risk of retrograde dissection of an old stenosing duodenal ulcer, the importance of peroperative recognition of this accident by cholangiography, the interest of sphincterotomy to attempt to prevent secondary stenosis of the papilla, the absolute necessity of an anastomosis preventing anastomotic ulcer by contact between the mouth of the gastro-enterostomy and the alkaline secretions. Vagotomy seems to them a useful complementary procedure but, associated with a drainage procedure, they believe it might have avoided this severe complication.

Adult↗