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Biomedical subjects

M Merle

Publications and source records attributed to M Merle.

At least 235 records · Page 13Linked to original sources
PubMed1977

Continuous blood velocity and flow measurements by intravascular elutherm probe.

A device for measuring the mean blood velocity (by means of a thermal equilibrium method) and the intravascular electrical impedance, which determines the mean sectional area of the vessel, have been mounted on the same probe (french catheter 7F). The validity, of the method has been confirmed in vitro and by 100 measurements carried out in dogs and compared with flow measurements by means of the cardio-green method. The correlation coefficient is found to be 0.98.

Animals↗
PubMed1975

[Lymphocyte depletion through experimental anastomosis of the thoracic duct and cervical esophagus].

In 25 dogs, a short segment of the left subclavian vein, adjacent to the connection of the thoracic duct, was dissected free with its jugular branch and ligated. An end-to-side anastomosis, using interrupted sutures was performed in two layers, between the side of the cervical esophagus and the proximal part of the jugular vein. This vein, acting as a reservoir, remains connected to the thoracic duct by the isolated segment of the subclavian vein. The original aspect, of our technique is the use of a catheter placed into a branch of the vein near the site of the anastomosis and through which a saline solution with heparin (1 mg/kg) and penicillin (40.000 U/kg) is injected daily. The catheter emerged on top of the dog's neck, and continuous perfusion was provided by a chronofusor. The catheter was removed after one month. In 30% of the dogs, the anastomosis was found patent after more than 6 weeks. This has been proved by fibro-esophagoscopy after injection of a solution of patent blue in the jugular catheter ; lymphangiograms obtained by direct injection of radio-opaque material through the jugular catheter, and a decrease in lymphocyte counts to 4% of the total white blood cell count, compared to 30% in the controls. There was no significant loss of weight in the surviving dogs.

Animals↗