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Biomedical subjects

M Merlier

Publications and source records attributed to M Merlier.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Bronchopulmonary hamartochondroma (apropos of 136 cases, including a homogeneous series of 124 cases). Review of the literature].

On the basis of a series of 136 hamartochondromas, the largest ever published, the authors review the clinical and paraclinical characteristics of bronchopulmonary hamartochondromas. After describing their pathological study, particular attention is paid to the controversial pathogenesis of these tumors before dealing with therapeutic aspects. Review of the literature.

Adolescent↗
PubMed1984

[Long-term survival of patients operated on for primary bronchial cancers (excluding anaplastic cancers)].

The results of a retrospective study of patients operated upon for primary bronchial carcinoma (small-cell type excluded) are reported. The survival rates of 1285 patients who underwent tumoral excision between 1960 and 1973 were calculated by the actuarial method after exclusion of post-operative deaths. The overall survivals at 5 years' intervals were 31%, 18%, 11% and 8%. The excess mortality due to cancer was significant up to 15 years. Among 159 patients who survived for more than 10 years, relapses or new growths, sometimes amenable to surgical treatment, were relatively common. The cardiorespiratory status, living conditions and social rehabilitation of 149 patients who survived for more than 5 years showed good adaptation in most cases. The long-term prognosis was unrelated to age, sex or side of the tumour. The influence of the histological type depended on differentiation. Among surgical operations, lobectomy had the best prognosis. In patients who had simple pneumonectomy there was no significant difference between pneumonectomies performed on account of tumour of the main bronchus and the others. The place of enlarged pneumonectomy is defined. Of paramount importance for survival are the T.N.M. classification (UICC coding modified by Renault in 1975) and Carr's grading into 3 stages of increasing severity, notably the size and site of the tumour (T1 to T3) and the presence of pedicular or mediastinal lymph node involvement (N1-N2-N3). Early diagnosis is essential. Prospective studies involving several parameters (especially treatments combined with surgery) appear to be needed.

Carcinoma, Bronchogenic↗
PubMed1984

[Results and prognostic factors in surgically treated thymoma. Apropos of a series of 194 cases].

The authors analyse a series of 194 thymomas (epithelial tumours of the thymus gland) which were operated over a period of about 25 years. The long term prognosis (70% 5 year survival and 60% 10 year survival) is examined in terms of the anatomo-surgical stage of the thymoma, the histological type of the tumour and the presence of associated auto-immune diseases. The authors recommend a more rigorous classification which takes into account both the anatomo-surgical and the histopathological findings so that the indications for post-operative mediastinal irradiation can be extended in a attempt to reduce the rate of distant recurrence of these tumours.

Autoimmune Diseases↗
PubMed1983

Pulmonary arterial embolus by an unusual wandering bullet.

We report on a wandering bullet embolus to the left pulmonary artery after it had first passed from the right ventricular to the right renal vein via the inferior vena cava. Its presence in the left pulmonary artery was confirmed by pulmonary angiography. Hemorrhage due to the right ventricular wound was controlled by a median sternotomy and the bullet was extracted by left lateral thoracotomy. Intravascular migratory bullets continue to be a surgical curiosity. Clinical diagnosis may present a difficult aspect in emergency practice and angiography is mandatory. The removal of foreign bodies is recommended by the majority of authors.

Adult↗
PubMed1982

[Isotopic scintigraphy in the diagnosis of the spread of bronchial cancer].

Ventilation of the lungs using Xenon 133 and perfusion scans using 99m Tc albumin particles in microspheres were performed on 455 patients with bronchial cancers and 55 patients with pulmonary metastases. Ventilation-perfusion mismatch and functional defects of the lung, which are never found in nodular-shaped pulmonary metastases, vary in frequency according to the anatomo-pathological type of the tumor and constitute a limiting factor for ablation.

Carcinoma, Bronchogenic↗
PubMed1982

[Tracheal resection for tracheal tumors (excluding cancer)].

Tracheal resection was performed in 10 patients with non-malignant tracheal tumors. Clinical, histological, and technical features are discussed, particular emphasis being given to long-term results. These tumors, mostly cylindromas (7 out of 10 cases in this series) are amenable to very wide surgical resection of the resection-anastomosis type. Suggested treatment for cylindromas should include systematic postoperative irradiation, as this considerably improves long-term (10 and 15 years) results.

Adult↗