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Biomedical subjects

M Merlier

Publications and source records attributed to M Merlier.

At least 73 records · Page 4Linked to original sources
PubMed1977

[Leiomyomas of the esophagus. Report of 20 cases (author's transl)].

The authors report 20 cases of leiomyoma of the esophagus operated on between 1964 and 1976. The diagnosis depended on the existence of dysphagia without loss of weight, the integrity of the mucosa on endoscopy and the findings of the esophagogram, suggested the true origin of the mediastinal image. Surgical operation usually permits simple enucleation of the leiomyoma. Postoperative mortality was nil. The late postoperative period was uneventful. There was no relapse of the histologically benign leiomyoma.

Adult↗
PubMed1977

[Surgery of 19 bilateral simultaneous pulmonary metastases].

19 patients with bilateral simultaneous pulmonary metastases were operated on between 1954 and april 1976 at the Marie-Lannelongue surgical centre. Sarcomas were twice as common as carcinomas. In 10 cases the thoracotomy was only unilateral, either because thoracotomy was not attempted on the other side owing to the diffuse nature of the lesions (8 cases) or because prior chemotherapy had permitted complete reduction of the metastases on the opposite side (2 cases). This thoracotomy remained exploratory in 47 p. cent of cases, radical removal of all the tumour nodules was possible in 53 p. cent of cases (10 patients). Peripheral resections of the lesions were the rule. But in 4 cases, lobectomy was carried out on one side. 7 of the 9 bilateral operations were performed during the same stage. There were no operative deaths. The late results are encouraging considering the number of sarcomas in which the prognosis is usually poor. Bilateral lesions are thus not an absolute contra-indication, provided one remains within reasonable anatomical and functional limits, in the fields of well-conducted anti-cancer strategy.

Adolescent↗
PubMed1976

[Profile of surgical tumors of the mediatinum. Apropos of a series of 742 operated patients].

The authors seek to draw statistical conclusions on the basis of 742 surgically treated mediastinal tumours. Tumours of the thymus were the most common (20%). They were followed by tumours of the thyroid, neurogenic tumours, haematosarcomas and mediastinal cysts - all with an occurrence rate of around 12 to 15%. From a histological standpoint, 34.5% of the tumours were malignant or "potentially malignant". After a topographical study of these tumours, the authors discuss the possibilities of surgical treatment, the latter being great even in the case of malignant lesions.

Humans↗
PubMed1976

[Anatomo-clinical calssification of primary tumors of the pleura and possibility of their surgical treatment].

A distinction is drawn between first category includes peduncolates, giant seslocal and diffuse primary tumours of the pleura on anatomopathological grounds. The first category includes peduncolated, giant sessile, and "deceptive" forms; the latter those in which the lung is surrounded by a "pleural" and "serous" mantle. Treatment is discussed and the soundness of surgical management is stressed.

Diagnosis, Differential↗
PubMed1976

[71 pulmonary hamarto-chondromas].

Seventy-one hamarto-chondromas were operated on at the Centre Chirurgical Marie-Lannelongue from January the 1st 1958 to September the 1st 1975. Pulmonary hamarto-chondroma is always a slowly evolving benign tumour, usually found in patients between 40 and 60, and twice as frequent in males as in females. There are two different kinds. 1) Intraparenchymal hamarto-chondromas, which have a noteworthy clinical latency and in 2 cases out of 3 are situated anteriorly and peripherally. The usual treatment consists of simple enucleation. 2) Endobronchial hamarto-chondromas, on the other hand, have a striking symptomatology of bronchial obstruction. If operated on after some delay, they will cause the destruction of distal parenchyma. Treatment depends on their topography. Segmental resection is often the sole recourse.

Adolescent↗
PubMed1976

[Surgical treatment of pulmonary metastases from rectocolic cancers. Apropos of 21 cases].

The authors report 21 cases of pulmonary metastases from operated cases of rectal and colonic carcinoma. Half the patients were aged between 60 and 70 years. In all cases except one the primary tumour was known and treated surgically before the metastasis occurred. The authors emphasize the necessity of radiological supervision of the chest after operation and recall that neither chemotherapy nor radiotherapy should be undertaken without prior histological confirmation. It is possible to remove the metastases by surgery but a high percentage require pneumonectomy i.e. it is necessary to take the same precautions before operation as for primary carcinoma of the bronchus. The operative mortality was nil, and the five year survival rate 18 p. 100.

Adult↗