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Biomedical subjects

M Merlini

Publications and source records attributed to M Merlini.

At least 55 records · Page 3Linked to original sources
PubMed1984

The toxicity of tritium: the effects of tritiated amino-acids on preimplanted mouse embryos.

The effects of tritiated amino-acids, arginine, lysine, histidine and aspartic acid on the growth and development of two-cell mouse embryos, cultured in vitro, were investigated. The LD50 for the dibasic amino acids, measured on the third day of growth, ranged from 30 to 130 nCi/ml. This was compared with the DNA precursor, thymidine, for which the LD50 was 80 nCi/ml.

Amino Acids↗
PubMed1983

[Treatment and prognosis of colo-rectal cancer. Study of 1357 cases].

This retrospective report deals with 1357 cases of colorectal cancer operated on in the last 26 years. It covers the main epidemiologic data, tumour locations, surgical approaches, follow-up and prognosis according to the extent of the cancer. The results are given for the entire period and then by fractions thereof, and it is thus possible to appreciate how the treatment and prognosis of colorectal cancer have evolved. Though a high proportion of advanced cancer has been observed throughout the period studied, progress has been made in early diagnosis in particular: an increasing number of patients (13.5%) are nowadays operated on for tumours in situ or Dukes A.

Adenocarcinoma↗
PubMed1982

[Urethral complications of severe fractures of the pelvis. (author's transl)].

Between 1975 and 1979, 282 fractures of the pelvis were treated in Centre Hospitalier Universitaire Vaudois' sixty-eight of these patients sustained severe fractures, with two or more rupture of the pelvic ring. Twenty-eight patients presented with hematuria (microscopic or macroscopic) and five others with urethral bleeding. Urethral bleeding is even more serious; in the present study, it was always associated with urethral rupture. These cases are discussed; mechanism, diagnosis and treatment of these injuries are described.

Adult↗
PubMed1980

[Immediate vascular complications of severe pelvic fractures. Diagnosis and treatment].

Between 1975 and 1979 282 patients were treated for fractures of the pelvis at the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Sixty-eight had severe fractures with two or more ruptures of the pelvis. Twelve of these patients also had vascular complications, viz. severe retroperitoneal hematoma, and rupture of the hypogastric artery or of the iliac vein. The histories, including the associated injuries, of these 68 patients were followed up from admission to hospital to discharge. The mortality was 11% for severe fractures of the pelvis and 33% in cases with vascular complications. The relative importance of diagnostic peritoneal lavage, angiography and surgery is stressed. Vascular embolization as an alternative treatment in the case of rupture of the hypogastric artery or branches is also discussed.

Angiography↗