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Biomedical subjects

M Meves

Publications and source records attributed to M Meves.

At least 37 records · Page 2Linked to original sources
PubMed1980

[The relationship between oral glucose tolerance and gastric emptying in duodenal ulcer patients (author's transl)].

In 50 patients with duodenal ulcer disease before the operation and early postoperatively after SPV there were performed simultaneously 54 measurements of halflife of gastric emptying (T 1/2) and of pattern of oral glucose tolerance curve. It could be shown that there is a close relationship between the type of disturbance of gastric emptying and the pattern of glucose curve. In addition it could be proved that there is a significant correlation between the T 1/2 and the 180-min.-glucose concentration.

Adult↗
PubMed1979

[Gastric emptying in patients with ulcus ventriculi (author's transl)].

The half life time (T 1/2) of gastric emptying was measured in 53 patients suffering from atrophic gastritis or gastric ulceration, by use of a radiolabelled standardized test-meal. In healthy controls the T 1/2 was 58.8 +/- 9.1 min (median 59 min). In 35 gastric ulcer patients the T 1/2 of median 85 min was significantly slowed if compared to the normal value (2 p less than 0.01). After healing of the ulcer in 12 patients this value returned to normal. In 8 patients with diffusely atrophic gastritis the T 1/2 value was slowed significantly (median 123 min), if the gastritis was confined to the antrum, gastric emptying was accelerated (median 48 min).

Adult↗
PubMed1979

[Gastric motility after vagotomy (author's transl)].

1. Ulcer disease cause a change of gastric emptying; in patients with gastric ulcer gastric emptying of a semisolid meal is delayed as well as in patients with stenosis in the pyloricregion; patients with an uncomplicated duodenal ulceration shows an accelerated gastric emptying. 2. Vagotomy results in relation to the type of vagotomy and to the degree of desection of anteral muscles a delay of gastric emptying of a semi solid and liquid food until over the 6th postoperative month. 3. After selective proximal vagotomy (SPV) the gastric emptying is also but shortly delayed. 4. There is a correlation between the disturbed gastric emptying after vagotomy and the altered absorption of glucose.

Duodenal Ulcer↗
PubMed1979

[Gastric emptying in duodenal ucler (author's transl)].

In 196 patients suffering from duodenal ulcer disease, gastric emptying was measured by use of a radiolabelled testmeal. The measurements were performed during the digestive phase of gastric activity. On the basis of the predominantly exponential form of gastric emptying the T 1/2 was chosen as a measure of this function. The results were: 1. In 50 subjects without gastrointestinal disease the median T 1/2 was 59 min, mean and standard deviation were 58.8 +/- 9.13 min; 2. the T 1/2 value in 71 patients with deformed duodenal bulb (median 53 min) was significantly accelerated if compared to the normal value (2 p less than 0.01); 3. T 1/2 in 88 patients with deformed bulb combined with acute ulcer (median 49 min) was shorter than T 1/2 of the normal subjects (2 p less than 0.001); 4. T 1/2 in 25 patients with pyloric stenosis (median 102 min) was longer than normal value (2 p less than 0.001).

Adult↗
PubMed1977

[Isolated stenoses and occlusion of the coeliac artery--a comparative angiographic and clinical study (author's transl)].

14 patients with occlusion (7 patients) or extreme stenosis (7 patients) of the arteria coeliaca underwent operation because of heavy abdominal complaints. The constriction of the arteria coeliaca was caused by arteriosclerosis (2 patients), ligamentum arcuatum medianum (8 patients), ligamentum arcuatum medianum and ganglion tissue (2 patients). For the restitution of a normal blood circulation in the epigastric organs the following was necessary: in 10 patients a decompression, in 3 patients an aortocoeliacal bypass and in 1 patients an enlargement plastic with vein patch. The angiographic findings indicate a connection between the arteria coeliaca occlusion or extreme stenosis and the extent of the collateral blood supply. High pressure gradients between aorta and arteria coeliaca, significantly decreased medium pressures in the arteria hepatica communis and noticably frequent morphologic changes in the epigastric organs could be seen intraoperatively.

Adult↗
PubMed1976

[Compression of the celiac trunk (author's transl)].

Besides the vascular changes caused by arteriosclerosis the compression stenosis is the most frequent form of the isolated restriction of the arteria coeliaca. The compression of the arteria coeliaca, caused by the ligamentum arcuatum medianum or a fribromatous ganglion tissue, can cause complaints similar to the symptoms of angina abdominalis: pains in the epigastrium, postprandial pains, loss of weight, nausea/vomiting, diarrhea, 93% of the patients with severe vascular compression have an abdominal vascular murmur. Of 31 patients with angiographically proved compression stenosis, 11 patients suffering from occlusion or intense stenosis had to be operated because of heavy complaints. The angiographic and intraoperative findings allow the conclusion that there is a connection between the extent of the stenosis and the clinical appearance. The decompression of the arteria coeliaca, in other words the detachment of the compressing tissue leads to total complaintlessness in 83% of the patients. If the arteria coeliaca is hypoplastic a vessel widening or a bypass operation is necessary to establish normal blood circulation in the epigastric organs.

Adult↗
PubMed1976

[Functional gastric diagnosis (author's transl)].

A method is described (isotope gastro-diagram) in which a radio-active labelled standard meal is used under physiological and phatological conditions; in this way the half-value time of gastric emptying can be used as an objective measure of gastric motor function, and which can be easily reproduced. This has become of clinical interest, particularly since the introduction of hypotonic and double contrast methods in radiological diagnosis. The clinical value of this method has been elucidated amongst surgical patients on whom pre- and post-operative measurements were carried out following selective vagotomies, combined with various types of pyloroplastry for the treatment of gastric and duodenal ulcers.

Chromium Radioisotopes↗
PubMed1976

[Hepatic vein angiography for the demonstration of intrahepatic tumours (author's transl)].

Fifteen patients with suspicion of metastases of the liver were examined in order to demonstrate the angiographic signs and the diagnostic possibilities of retrograde hepatic vein angiography. By this method, in all of our patients a scintigraphically doubtful or suspicious finding could be cleared up. Since hepatic vein angiography is superior to arteriography, sonography and scintigraphy with regard to identification of minor metastases, but is technically a complicated special examination, it should be applied as an extended diagnostic measure additionally to the other examinations.

Adult↗
PubMed1976

[Studies of the relationship of gastric motility, gastrin secretion and HCl biosynthesis in patients with duodenal ulcer].

Serum gastrin, acid output and gastric emptying were measured in patients with duodenal ulcer. 1. Eighty-two patients with duodenal ulcer evacuate a semisolid meal with differing patterns: rapid (n = 24), normal (n = 46), and delayed (n = 12). 2. Comparing patients with rapid and delayed gastric emptying, basal and peak serum gastrin and integrated gastrin output are significantly higher in the rapid emptying group.

Adult↗
PubMed1975

[Diagnosis and operative treatment of coelic-artery compression].

Stenosis of the coeliac artery by compression occurs predominantly in youngish patients and three times more frequently in women than men. It gives rise to abdominal symptoms, due to chronic disturbance of intestinal arterial supply. In eight patients, operated on for this condition, the characteristic symptoms were of abdominal pain, epigastric vascular sounds, loss of weight, nausea and vomiting. Diagnosis could only be made by angiography of the coeliac and (or) mesenteric arteries, and lateral aortography. Analysis of 240 cases reported in the literature indicates that the condition is caused by compression of the coeliac artery by the medial arcuate ligament of the diaphragm, and only in a few instances by nerve tissue of the mesenteric ganglion of the coeliac plexus. Operative treatment (decompression of the artery) removes symptoms in 83% of cases.

Adult↗
PubMed1975

[Extragastric gastrin liberation. Studies on patients following gastrectomy and duodenopancreatectomy].

28 investigations were performed in control patients with no gastric disease (n equals 10), in patients after total gastrectomy (n equals 10) and in patients after duodenopancreatectomy (n equals 8). We measured the serum gastrin concentrations in the fasting state and after the ingestion of a test meal. The results indicate that more than 60% of the gastrin activity is released from extragastric sites and in addition, it is supposed that about 20% are released from extragastric and extraduodenal sites.

Aged↗