Biomedical subjects

M Miguil

Publications and source records attributed to M Miguil.

12 recordsLinked to original sources

PubMed2004

Spontaneous cervical epidural haematoma during pregnancy.

Spontaneous cervical epidural haematoma is very rare during pregnancy. We describe a woman who presented with tetraplegia at 41 weeks of pregnancy. She had no previous history of any relevant medical disorder. Her upper level of anaesthesia was at the second thoracic segment. The condition was diagnosed by magnetic resonance imaging, and both caesarean section and decompression were conducted 12 hours after the event. The neurological deficit showed little recovery. Histology was non-specific and follow-up magnetic resonance imaging showed spinal cord ischaemia. The prognosis in this condition depends on the interval of time between onset and decompression.

Adult↗

PubMed2004

Pneumomediastinum and pneumothorax associated with labour.

A 19-year-old primiparous woman in labour presented with spontaneous pneumomediastinum, pneumothorax and surgical emphysema. The membranes were intact and the fetus had a breech presentation. There was little improvement in her symptoms and labour progressed slowly. A caesarean section was performed under intrathecal block resulting in the birth of a healthy infant. The patient's symptoms resolved with supportive management. This condition is very rare and is generally self-limiting. Management aims to avoid worsening of pneumothorax and pneumomediastinum. Recurrence is unlikely.

Adult↗

PubMed1998

[Postpartum cerebral thrombophlebitis. A case secondary to acquired antithrombin III deficiency].

The cerebral thrombophlebitis is a rare complication of the pregnancy and the postpartum. We report a case of a 21 year-woman presenting a post-partum cerebral thrombophlebitis, secondary to an acquired deficiency of antithrombin III. The clinical symptoms of cerebral thrombophlebitis can be misleading. The angiography and the magnetic resonance imaging permit the diagnosis. The treatment is relied on anticoagulating heparin therapy. This treatment will be adapted in case of coagulation's factors deficiency that must be searched in any thromboembolic accident having an unusual localization.

Adult↗

PubMed1998

[Critical analysis of hemostasis disorders in the course of eclampsia. Report of 106 cases].

OBJECTIVE: Study of hemostatic disorders during eclampsia, their risk factors, maternal complications and associated mortality. METHODS: Retrospective study concerning 106 cases of severe eclampsia treated in intensive care between September 1992 and December 96. Patients with or without hemostatic disorders were compared for laboratory findings, maternal complications and mortality. RESULTS: Forty patients had hemostasis disorders as follows: isolated thrombopenia in 19 cases, disseminated intravascular coagulation (DIC) in 5 cases, Hellp syndrome associated to DIC in 7 cases and Hellp syndrome in 9 cases. Hemostasis disorders were associated to maternal advanced age, but not with gestational age or blood pressure in admission or time of convulsions. Complications and mortality associated with hemostasis disorders were more frequent compared to patients without hemostasis disorders. Among the 17 deaths of our series, 10 had hemostasis disorders. CONCLUSION: Hemostasis disorders were prognosis factors in eclampsia requiring systematic laboratory tests at admission and immediate delivery.

Adult↗

PubMed1996

[Mesenteric infarction secondary to antithrombin III deficiency].

AT III is a physiologic inhibitor of blood clot formation: its deficiency is manifested by venous thrombosis. The authors reported case of mesenteric venous infarction in a 42-years-old woman. AT III deficiency was transient and caused by an oral contraceptive. In patients with AT III acquired deficiency it is necessary to suppress any risk factors of venous thrombosis.

Adult↗

PubMed1995

[Acute phostoxin poisoning].

Phostoxin is a mixture of aluminium phosphide and ammonium carbonate. When exposed to water, it releases phosphorus hydrogen (PH3), a highly-poisonous gas. In Morocco, death rate from suicide due to self-administration of phostoxin pills is high. Clinical signs include abrupt digestive and nervous disorders. Pulmonary oedema or cardiogenic shock dominate early prognosis. Liver and renal damage is secondary. Prevention requires both legal constraints and regulation of sales.

Acute Disease↗

PubMed1995

[Fatal hepatic necrosis during treatment with sodium valproate].

The authors report a case of fatal hepatic failure in a 19-year old young man suffering from absence seizures and treated for two months with valproic acid (VPA). The duration of VPA therapy before onset of clinical manifestations was four weeks. The prodromal symptoms were weakness, anorexia, and vomiting, then in a few weeks occurred a jaundice and an hepatic encephalopathy leading to death. Among laboratory findings disturbance of liver tests and particularly depressed levels of clotting factors were observed. The histologic study of the liver showed an extended centrolobular necrosis associated with fatty change and fibrosis. The mechanism of this hepatic failure remains unknown. The seriousness of this complication necessitates to respect any contraindications.

Adult↗

PubMed1994

[Pulmonary edema following laryngospasm in a child].

A case is reported of a pulmonary oedema secondary to a laryngospasm in a 10-year-old child during a scheduled orchidopexy. Anaesthesia was induced with 50% nitrous oxide in oxygen and halothane via a face mask. Pulmonary oedema occurred before the relief of the laryngospasm and its course was uneventful after tracheal intubation and mechanical ventilation with PEEP. Hydrostatic forces or an increased capillary permeability are likely causes of the oedema. The outcome is usually favourable.

Anesthesia, Inhalation↗

PubMed1994

[Cerebral complication in eclampsia].

Many brain complications occur during eclampsia with various degree of gravity. The pathogenesis of these lesions continues to be a source of considerable controversy. Five cases of eclampsia with severe neurologic manifestations were treated in our surgical intensive care unit. The CT image appeared to be related to haemorrhagic lesions (3 cases) and ischaemic lesions (2 cases). The clinical course was favourable, often reversible, in cases with oedema and ischaemia maternal prognosis was poor in the case with haemorrhage.

Adolescent↗

PubMed1994

[Acute hepatic steatosis in pregnancy can be cured without interrupting the pregnancy].

Fatty liver during pregnancy is an acute hepatic disease of unknown origin. We report the case of a 24-year-old woman in whom the diagnosis was made on the basis of the histological examination. The disease did not disturb the normal course of the pregnancy and delivery. In the literature, it is generally suggested that pregnancy must be terminated in cases of acute fatty liver since no favourable outcome has been reported with continued pregnancy. We suggest that, in minor forms, close clinical observation and laboratory monitoring can provide the means of continuing the pregnancy to term.

Abortion, Therapeutic↗

PubMed1992

[An unusual case of HELLP syndrome].

The Hellp's syndrome is a complication of gravidic hypertension which associates the microangiopathic hemolysis, the cytolytic hepatic anomalies and a thrombocytopenia. There are resemblences between the biologic and histologic forms of the thrombotic microangiopathy and Hellp's syndrome. In this publishing, we report one case of Hellp's syndrome which the particular character is that the hepatic and hemolytic biologic anomalies are still very discrete, where as the thrombopenia is deep; this led us to rediscuss about the authencity of Hellp's syndrome. A neurologic complication, particulary gravissim, is noticed in one case, it concerns the intracerebral hematoma with left deficiency syndrome.

Adult↗

PubMed1991

[Severe hemobilia of cholecystic origin].

The authors report a case of severe hematobilia originating in the gall bladder itself ans associated with a cholecysto-colic fistula. They review the different etiologies of hematobilia and stress the major value of selective arteriography of the coeliac trunk and possible pitfalls in this condition. This case highlights the rare complications of cholelithiasis (hematobilia and cholecyto-colic fistula) and the severity of blood spoliation. Therapy is reviewed as a function of the lesion causing hematobilia.

Angiography↗