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Biomedical subjects

M Milev

Publications and source records attributed to M Milev.

At least 19 recordsLinked to original sources

[Work test in acquired heart valve defects].

The physical working capacity to 34 patients with acquired cardiac valvular defects and right catheterization was determined via bicycle ergometer "Zimermann" (GDR). Reverse correlation was established between the physical capacity and pressure 0,93 +/- 0,13 kPa (7,0 +/- 1,0 mm Hg) in right auricle (p less than 0,01), 0,9 +/- 0,27 kPa (6,75 +/- 2,12 mm Hg)--in right auricle (p less than 0,01), 4,18 +/- 1,21 kPa (31,5 +/- 9,02 mm Hg)--in pulmonary artery (p less than 0,05) and 2,66 +/- 0,26 kPa (9,19 +/- 6,76 mm Hg)--in pulmonary capillaries (p less than 0,5). The data from the study coincide with those of the other researchers who established reverse correlation between the physical working capacity and functional class according to New York Cardiological Association. The degree of mitral-valvular stenosisin "pure" or dominating mitral stenosis, degree and duration of cardiac insufficiency, duration of cardiac defect and auricular fibrillation.

Adult↗

[Cleansing and disinfecting the skin of calves in veal production].

Investigations were carried out at 6 meat producing combines on calves intended for slaughter. The animals originated from farms of different hygiene conditions. The studies aimed at establishing the extent to which the produced meat was contaminated with organisms coming from the skin cover. The total count of bacteria as well as that of coliforms in samples taken from the coat of calves were determined prior to bathing the animals, after that and after disinfection. Following slaughter the bacteria were studied at the site of separating the skin, in the abdominal muscles and in the croup. The skin of the calves for slaughter was found to be strongly contaminated with bacteria. The bathing and the disinfection with a 2 per cent chloramine solution decreased the number of microbes, however, did not fully inactivate bacteria. This contributed to the additional surface contamination of the meat obtained.

Animals↗

[Methods for the control of disinfection in meat-packing plants].

Forty-eight series of experiments were carried out to establish the effect of disinfections with 2% septin, 1% tagonin, 2.5% chloramine and 2% chlorinated lime, all applied in the meat processing shops. Determined were the total count of bacteria and that of coliforms alone, employing the methods of washings and taking impression (contact) samples (Schothorst et al., 1966). It was found that these disinfection agents did not produce a complete disinfection effect. The contact method of determining the total count of bacteria proved readily applicable and suitable to investigate subjects having smooth surfaces. The combined use of the two methods to record the effect of disinfections is, however, suggested because of the diversity of the various subjects in the meat processing shops.

Bulgaria↗

[Intracardiac hemodynamic characteristics in high-degree mitral stenosis and an assessment of the indications for its surgical treatment].

The data from the right cardiac catheterization, echocardiography M-type and radiocardiography were juxtaposed in 54 patients with "pure" or predominating severe mitral stenosis (MS)(mitral valvular opening under 1 cm2)--confirmed at operation, in the determination of their functional and hemodynamic characteristics. The patients were grouped into three groups depending on the degree of pulmonary--capillary pressure increase (PC)--greater than 2.666, greater than 3.999 and 4.132 kPa(greater than 20, greater than 30 and less than 31 mmHg). The first group covering 28 per cent of the patients with a mean PC--2,399 +/- 0.257 kPa = (18 +/- 1.93 mmHg) are of particular interest. A light to moderate increase of pulmonary arterial pressure, elevated TPVR, absence of right ventricular insufficiency with reduced M. V SI resp. were established in them. It was assessed as a group with hypovolemia and proper preoperation preparation but requiring attention as regards the eventual hypotension, intra- or post operation. The third group covers 22 per cent of the patients and is characterized with increased TPVR, high hypertension in pulmonary artery, elevated telediastolic pressure in right ventricle and normal or lightly increased MO, assessed as a group with an inadequate diuretic therapy pre-operatively. The second group is with typical hemodynamic characteristics of severe MS and includes 50 per cent of the patients. The analysis forces the conclusion, that for an adequate evaluation of hemodynamics and MS severity, the PC pressure is necessary to be always discussed in connection with blood volume and flow, as well as with the other hemodynamic indices, in order to avoid the omissions as regards MS operability.

Adult↗

[Microbiological study in pork production].

Investigations were carried out in production conditions on the sources of surface contamination of pork with regard to sanitary-indicative and pathogenic (Salmonellae) organisms. A total of 74 series of experiments were carried out, every series making use of the following: 10 fecal samples taken on the preslaughter premise; the results of studying the skin cover of 3 animals prior to washing, after washing, and after stunning, employing the method of Dryabina in studying skin areas of 25 cm2; as many as three washings taken from within the path from the place where the animals were washed to the place where they were stunned; the results of studying the surface of the meat produced (from 3 animals in each case) and at the site of starting skin removal, with sampling the abdomen muscles and the group along with sampling the meat itself after cleaning and washing it - taking impression preparations, resp., employing the contact method with a 44 cm2 surface area of the agar. No Salmonella bacteria were found in the 1628 analyses and fecal samples of the skin of pigs intended for slaughter. The washing of the animals lowered more than 70 times the total bacterial contamination of the skin cover. It was found that the site of starting skin removal and the muscles of the abdomen and those of the forelimbs were most strongly contaminated.

Animals↗

[Structure of the Salmonella from animals, birds and the environment through the period of 1970-1975].

Studied were biochemically and serologically the species of a total of 8738 Salmonella cultures. Most of the investigated strains belonged to subgenus I--95 species; to subgenus II belonged one species (Salmonella sofia); to subgenus III belonged 4 species: Salmonella arizonae 11:b:1, 7; Salmonella arizonae 35:r:z35; Salmonella arizonae 35:z52:1, 5, 7; Salmonella arizonae 58:rz53:z57 of three serologic groups. The attention was focused on more than 20 (new to this country) Salmonellae among which a Salmonella bulgaria species new to the Salmonella genus. Data are given for the origin of the strains, the biochemical and serologic behaviour, the sensitivity to phage O1 and the phage types of Salmonella typhimurium and Salmonella enteritidis.

Animals↗

[Normal status of Bac. cereus and Cl. perfringens in the body of healthy slaughter animals].

Studied were cattle, pigs, sheep, and young calves intended for slaughter. The experiments were carried out under productional conditions, strictly observing the routinely adopted practice of preslaughter handling. The blood of the animals was sampled prior to slaughter. Samples from the meat (musculature), spleen, kidneys, liver, mesenterial and body lymph nodes as well as feces were taken immediately after slaughter. It was established that Bacillus cereus and Clostridium perfringens were almost lacking in the musculature, mesenterial and body lymph nodes and in some of the parenchymal organs. These organisms were chiefly found in the intestinal tract. Eighty-three up to 100 per cent of the isolated cultures of Cl. perfringens and from 62.5 up to 100 per cent of the isolated cultures of Bac. cereus originated from the feces.

Animals↗

(Vitamin B-12 in ground meat)

Studied was the vitamin B12 activity of minced meat obtained under productional conditions from freshly cooled (24 hours after slaughter) veal and pork. It was found that the vitamin B12 content of the minced meat one hour after it had been obtained varied within the range of 0.0373 to 0.0432 micrograms per 100 g of dry matter. Later in the production process its activity turned out to be closely related to the temperature and period of storage as well as to the microbial content of meat. Cyanocobalamin is said to be the fraction that is most often established in mined meat, and very rarely some other fractions are found, such as Factor I (B12--Factor III).

Animals↗