PubMed Health⌕ Search

Biomedical subjects

M Minuck

Publications and source records attributed to M Minuck.

At least 19 recordsLinked to original sources
PubMed1976

Cardiac arrests in the operating room-Part I. (1965-1974).

A ten-year review of the incidence of cardiac arrest in the operating suite at the St. Boniface General Hospital has been presented. Seventy cardiac arrest occurred during this period, and 29 were permanently resuscitated for a survival rate of 41.4 per cent. This rate compares favourably with the published experince of other centres. It does not, however, reflect an improvement over the survival rates published prior to 1960, a point in time when direct cardiac compression for the management of these cases was virtually abandoned in favor of external cardiac compression. To improve survival, a plea is made for return to early use of thoracotomy and direct cardiac compression in the treatment of cardiac arrest in the operating room. To accomplish this end all surgeons and anaesthetists should become familiar not only with the techniques required for these procedures, but also with the prevention and management of any associated complications.

Adolescent↗
PubMedDate not supplied

Comparison of THAM and sodium bicarbonate in resuscitation of the heart after ventricular fibrillation in dogs.

Tris (hydroxymethyl) aminomethane (tromethamine or THAM) has been suggested as an effective substitute for sodium bicarbonate (NaHCO3) in the treatment of metabolic acidosis accompanying cardiac arrest. Even though several reports on its appraisal have been published, there is still no clear agreement on its therapeutic value. A double-blind study was therefore lndertaken to compare in 36 dogs the effectiveness of 0.6 M THAM, 0.3 M THAM, and NaHCO3 (0.892 mEq/ml) to correct metabolic acidosis produced during 3 minutes of cardiac fibrillation, followed by a 3-minute period of cardiac compression. The dogs were then defibrillated and observed for 45 minutes. One group of 8 dogs was treated with 0.9 percent NaCl infusion. Compared with 0.9 percent NaCl, both THAM and NaHCO3 were equally effective in correcting metabolic acidosis (p less than 0.05). Initially, 0.6 M THAM produced a more pronounced (p less than 0.05) elevation of blood pH, but this effect was not sustained during the later postdefibrillation period. There was little difference in the effect of either of these drugs on mean aortic pressure and total peripheral vascular resistance. It is concluded that adequate ventilation and effective cardiac compression are still the chief criteria on which the final outcome of cardiac resuscitation depends. Correction of metabolic acidosis is important supportive therapy, but either THAM or NaHCO3 can be used with comparatively equivalent effect.

Acidosis↗