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Biomedical subjects

M Misiuk-Hojło

Publications and source records attributed to M Misiuk-Hojło.

18 recordsLinked to original sources
PubMed2000

[The role of electrooculographic examinations in the glaucoma diagnosis].

PURPOSE: To evaluate the significance of the electrooculography in the diagnosis of glaucoma. MATERIAL AND METHODS: We studied 31 patients with primary open-angle glaucoma (aged 22-69 years), 29 patients with normal-tension glaucoma (aged 19-77 years) and 22 healthy controls (aged 38-65 years). We performed routine ophthalmological examinations and electrooculography in all patients. RESULTS: Arden's coefficient results concerning electrooculography were the highest in control group and the lowest in primary open-angle glaucoma group, but the differences were not statistically significant. CONCLUSION: Electrooculographic examinations do not seem to be effective for detecting glaucoma.

Adult↗
PubMed1999

[The behavior of angiotensin-converting enzyme in patients with uveitis].

UNLABELLED: Serum angiotensin-converting enzyme (ACE) is considered as a marker in many disorders, especially in sarcoidosis. The aim of this study was to assess ACE activity using Haiakari spectrophotometry in patients with non-sarcoidosis uveitis before and after treatment. MATERIAL AND METHODS: 36 patients, including 21 adults and 15 children, were investigated. ACE concentration was increased mostly in patients with recurrent toxoplasmic and toxocaral iridocyclitis and choroiditis. RESULTS: It was demonstrated that concentration of ACE was increased especially in toxocariasis uveitis. After treatment the concentration of ACE was significantly decreased in all patients.

Adult↗
PubMed1997

[Coexistence of migraine and glaucoma-like visual field defects].

PURPOSE: Functional and morphological evaluation of the optic nerve heads in patients suffering from migraine. MATERIAL AND METHODS: 21 patients--13 women and 8 men (mean age 40 +/- 10) with neurologically confirmed diagnosis of common and classic migraine were examined. The headache history was obtained by standard questions. The patients suffered from migraine from 2 to 30 years and the frequency of attacks was from < 10 to > 100/year. Ophthalmologic examination involved evaluation of visual acuity, anterior segment, irido-corneal angle, retina and optic disc. In all cases optic disc photography, diurnal tension curve and two central visual field examinations with Octopus 101 programm G2 were performed. RESULTS: In all cases IOP was normal (< 21 mm Hg). In 4 eyes (2 patients) there was early glaucomatous-like damage of the optic disc, without visual field defect. In most of these patients the optic nerve head looked normal, in part of them slightly pale. In 28% patients glaucomatous-like visual field defects were found (MD-3.9 dB to 6.6 dB). There was statistically significant relationship between increase of MD and frequency of migraine attacks (Mann-Withney U test, a = 0.05). CONCLUSIONS: Static perimetry of the central visual field has high diagnostic value in ocular vasospastic syndrome. Functional dysregulation of the optic nerve head circulation in patients with migraine might be involved in the pathogenesis of normal-tension glaucoma.

Adolescent↗
PubMed1997

[The role of cytokines in ocular inflammation].

In this paper the immunological mechanisms connected with cytokines in the intraocular inflammation were discussed. The attention was paid to the possible involvement of a cytokine--network in the development of uveitis.

Animals↗
PubMed1996

[Early diagnosis of optic nerve neuropathy in multiple sclerosis].

PURPOSE: To evaluate diagnostic sensitivity of clinical tests in optic demyelinating neuropathy. MATERIAL AND METHODS: We examined 21 persons (38 eyes) with confirmed sclerosis multiplex (SM) with no episodes of posterior optic neuritis in the history of the disease. The examination method included: Static perimetry of central visual field (30 degrees, by Octopus 101), pattern visual evoked potentials (p VEP), colour photographs of optic disc and magnetic resonance imaging (MR) of central nervous system, optic nerves and optic chiasm. Visual acuity and colour vision were normal. RESULTS: There was statistically significant elongation in the latency of P 100 in pattern VEP (> 118 ms, 3 x SD), and significant reduction in mean light sensitivity (MS) in central visual field. MRI revealed demyelinisation in cortex and/or spinal cord of all patients and demyelinating lesion in optic nerve of one patient. There was no Gd-DTPA enhancement. In statistical analysis there was no correlation between results of pattern VEP, IMR, morphology of optic disc, and duration of SM, stage of the disease (in Kurtzke gradation scale) or age of patient. In regression analysis there were statistically significant relationships (p < 0.05) between results of central static perimetry, duration and stage of disease.

Adult↗
PubMed1996

[Central visual field in patients with multiple sclerosis without symptoms of optic neuritis].

PURPOSE: To estimate central visual field (30 degrees) of patients suffering from multiple sclerosis (SM). SM was confirmed by magnetic resonance imaging. MATERIAL AND METHODS: There was no posterior optic neuritis in the history of the disease. The visual acuity of examined the 28 eyes was 1,0. The results of static perimetry were analysed by regression analysis. RESULTS: There were significant relationships between mean sensitivity (MS) and duration of the disease, stage of the disease (in Kurtzke gradation scale) and age. Mean defect (MD) was significantly higher in the upper half of central visual field and between 15-30 degrees (p < 0.05). We observed positive relationships between MD, short time fluctuation (STF) and corrected loss variance (CLV). We found negative correlations between MS, MD, CLV and STF. Mean reliability factor RF was < 10%. CONCLUSION: Static perimetry seems to be a useful test in early diagnosis and monitoring of optic nerve neuropathy in SM.

Adult↗
PubMed1996

[Ocular complications in toadstool mushroom poisoning].

We present a case of a young man poisoned with Amanita phalloides. He survived thanks to intensive treatment, however he had multiple complications, including endophthalmitis in one eye, which was enucleated, and macular deposits in the second eye, which was affected by glaucoma.

Adult↗
PubMed1996

[Angioid streaks in Grönblad-Strandberg syndrome].

The authors present signs and symptoms in Grönblad-Strandberg syndrome and current opinions on therapeutic procedures in choroidal neovascularization where central vision is threatened. The publication includes a case report.

Adult↗
PubMed1994

[Posterior uveitis--clinical forms and experimental models].

The author presented contemporary views concerning etiology and clinical forms of endogenous posterior uveitis as well as the experimental models and histopathological studies of these diseases. The similarities between clinical and experimental forms of choroiditis are emphasized.

Animals↗
PubMed1990

[Postoperative complications with the use of implants for treatment of retinal detachment].

Complications of the retinal detachment surgery with the use of episcleral and intrascleral implants are presented. The authors are using biological materials (fascia lata, dura mater) as well as alloplastic materials (Lincoff's sponge). Among the postoperative complications following were seen: protracted reactions from the side of the ocular adnexa, intraocular haemorrhages, intravitreal exudates. The most severe from the observed complications was the atrophy of the sclera at the spot of implantation of the silicon sponge.

Adolescent↗
PubMedDate not supplied

[Hereditary macular degeneration in 3 generations].

The family was described, where the vitelliruptive macular degeneration with various morphological picture was diagnosed in four persons (two males and two females) on the basis of ophthalmoscopic examination as well as fluorescein angiography. Morphologic variability of this dystrophy may lead to diagnostic difficulties, what previously caused unnecessary treatment of two examined men as cases of "central choroiditis".

Adult↗
PubMedDate not supplied

[Retinal detachment of unknown etiology].

Cases of retinal detachment of undetermined aetiology were analyzed on the material of the Ophthalmological Department in Wrocław. Presented were the results of the surgical procedures taking into account the actual classification of the detachments. A positive anatomical result of the operation was achieved in 80 p.c. of patients, instead the improvement of the visual function was observed in only 56.5 p.c. of cases.

Adolescent↗
PubMedDate not supplied

[Experimental autoimmune uveitis and retinitis induced by S-antigen immunization].

Experimental autoimmune uveoretinitis (EAU) was induced in Lewis rats by a single injection in foot pads of S-antigen in complete Freund's adjuvant. Clinically, during the 2 nd week after immunization, EAU starts by acute anterior, lately--posterior uveitis. Peptide S2, located in the N-terminal region of S-antigen, has a regulatory effect on EAU, while peptide M is a pathogenic site inducing EAU. Antibodies directed at peptide S2 were observed in rats not developing EAU while high levels of antibodies directed at S-antigen and peptide M were present in all rats.

Animals↗
PubMedDate not supplied

[Use of soft contact lenses in the Riley-Day syndrome in a small child].

We present the observation of a boy treated in our Ophthalmological Department in Wrocław from the age of 6 months up to 6 years for the serious keratitis with ulceration. We diagnosed Riley-Day syndrome with regard to many associated pathological features. The efficacy of the local treatment improved after application of soft contact lenses.

Contact Lenses, Hydrophilic↗