High result in prostate specific antigen test.
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Biomedical subjects
Publications and source records attributed to M Mokete.
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OBJECTIVE: To determine the effect of perioperative distal vasal lavage with 50 mL of normal saline on subsequent time to azoospermia after vasectomy. PATIENTS AND METHODS: Seventy-two patients were prospectively enrolled and randomized to undergo vasectomy with or without vasal lavage. Infertility rates at 8, 10 and 12 weeks were compared for both groups and for those undergoing the procedure under local or general anaesthesia. Patient compliance for returning postoperative semen for analysis was also assessed. RESULTS: There was no statistically significant difference in infertility rates at 8, 10 or 12 weeks after vasectomy with or without vasal lavage. Vasectomies performed under local and general anaesthesia had comparable rates of infertility at 12 weeks after surgery. Compliance in providing semen for analysis was poor. CONCLUSION: The routine adoption of distal vasal lavage during vasectomy for contraception cannot be recommended. As compliance in providing semen for analysis was poor, the clinician has a responsibility to remind the patient of the consequences of such action.
BACKGROUND: Inguinal hernia surgery has undergone numerous advances in the last few years. This study analysed the changes in the practice of one surgeon in a district general hospital over a seven year interval. The effect of changing from Bassini to Lichtenstein repair in 1994 was evaluated. METHODS: The study involved two parts: first a search of a computerised database of inguinal hernia procedures, and second, postal audits of men who had an inguinal hernia repair in 1993 and 1994 with outpatient follow up for those with a possible recurrence. RESULTS: A total of 1037 hernias were repaired over the seven years. There was an increase in the proportion of day cases from 18% to 70% and the number of operations performed under local anaesthetic rose from 1% to 45%. The postal audits had response rates of 79% (1993) and 66% (1994). Some 5/98 (5%) recurrent hernias were identified from the 1993 (Bassini) patients compared with 1/67 (1.5%) from the 1994 (Lichtenstein) cohort. CONCLUSION: Lichtenstein hernia repair can be performed safely as a day case using local anaesthetic in the majority of patients and appears to have a lower recurrence rate than Bassini repair.
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One hundred and ten children were evaluated in a prospective study in Lesotho to determine the pattern of pediatric ocular injuries in a developing African country. The pattern was found to be the same as that of developed countries regarding increased incidence in boys, frequency of accidental, self-inflicted and assault injuries, and high incidence of corneal lacerations, traumatic cataracts, hyphemas, and lid lacerations. The pattern differed from developed countries in the absence of injuries due to arrows, airgun pellets (BBs), fireworks, toys and chemical burns, the absence of orbital fractures, intra-ocular metallic foreign bodies, and rarity of retinal detachment, and the generally poor visual results following perforating ocular injuries. An information campaign is advocated in Lesotho to aid in the prevention of pediatric ocular injuries.
One thousand two hundred and ninety-six pre-school and school children were examined in the first screening programme for ocular anomalies in Maseru, Lesotho. One hundred and eighteen children (8.9%) were found to have significant ocular anomalies requiring treatment. The most common anomalies included refractive errors, squint, convergence insufficiency, amblyopia, vernalis, lid abnormalities, leukoma cornea, and cataract. The importance of school screening for ocular anomalies in a developing African nation is emphasized.
Two hundred and fifty-two adults were evaluated in a prospective study in Lesotho to determine the pattern of ocular injuries in a developing African country. The pattern was found to be similar to that of developed countries regarding increased incidence in young males, high frequency of assault injuries, and high incidence of lacerations to lids, cornea and sclera. The pattern differed from developed countries in the low incidence of perforating ocular injuries associated with occupation, motor vehicles and sports, the absence of orbital fractures, metallic intra-ocular foreign bodies, the low incidence of retinal detachment, and the generally poor visual results following perforating ocular injuries. Additional ophthalmic facilities with improved medical transportation is advocated in Lesotho to improve the visual prognosis in ocular injuries.
Diabetic retinopathy was found in 47.8% of 153 consecutive diabetic clinic patients examined in Maseru, Lesotho. Background retinopathy was present in 78% of patients with retinopathy, compared with 22% with proliferative changes. While no difference in prevalence of diabetic retinopathy could be demonstrated between the sexes, an association between diabetic retinopathy and hypertension and peripheral neuropathy was observed. The prevalence and severity of diabetic retinopathy was significantly related to the duration of disease. The pitfalls inherent in comparing the results of the current study with other published reports are considered. Better epidemiological surveys are required to determine the true prevalence of diabetic retinopathy among different racial, ethnic, religious, and tribal groups in Africa.
A series of 18 epibulbar tumors are reported from Lesotho, a nontropical African country. The etiologic risk factors in epibulbar tumors are evaluated in termas of the environmental conditions present in Lesotho. The pathogenesis of epibulbar tumors is discussed in terms of histological progression from benign to malignant lesions following prolonged exposure to presumed etiologic risk factors.
The first survey of ocular problems in rural Lesotho was conducted by a visiting eye team and consisted of an examination of 1266 ophthalmic clinic patients at 15 representative sites throughout the country. The most common ocular conditions encountered were: conjunctivitis, refractive error, vernalis, senile cataract, glaucoma, corneal opacities and trauma. This disease pattern differs from most developing African nations for reasons of climate, geography and diet. The absence of disciform macular degeneration, narrow-angle glaucoma, and rarity of retinal detachment was noted. The educational impact of the survey, and its importance for future planning are suggested.
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Sixty-four Basotho patients underwent therapeutic penetrating keratoplasty in Lesotho, a developing African nation. The overall long-term success rate of 60.7% was comparable to similar series in developed countries. Analysis of variables found to significantly affect graft outcome included size of graft, anterior segment pathology, postoperative iris adhesion to graft wound, and onset of graft rejection during hospitalization or after discharge. McCarey-Kaufman medium was found to be highly successful for corneal storage up to seven days, and corneal transplantation across racial lines was not associated with increased immune rejection reactions.
Sixteen penetrating keratoplasties were performed in 14 patients less than 16 years old. Clear corneas were obtained in 62.5% of eyes with significantly improved vision in 56.2% of cases. The problems of postoperative treatments, complications, and amblyopia were found to be manageable. The visual benefits of corneal transplantation in selected cases in children appear to outweigh the difficulties and problems engendered by this procedure.