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Biomedical subjects

M Molho

Publications and source records attributed to M Molho.

33 records · Page 2Linked to original sources
PubMed1980

Pulmonary functional abnormalities after upper dorsal sympathectomy. A comparison between the supraclavicular and transaxillary approaches.

Results of pulmonary function studies were compared in two groups of 12 patients each, in whom upper dorsal sympethectomy was performed by the supraclavicular or by the transaxillary approach. Patients were evaluated clinically, radiologically and functionally before operation and again three weeks, three months and six months after denervation. Findings suggest that an increase in small airway resistance concomitant with some degree of pneumoconstriction occurred after upper dorsal sympathectomy by both routes. Musclar transection and possible phrenic nerve retraction damage due to the operative procedure could not be the cause of the above abnormalities because the inspiratory and expiratory forces, inspiratory peak flow and diaphragmatic movement were not significantly reduced after operation by both approaches. However, in a few cases, extrapleural hematomas, segmental atelectasis and relaxation of the daiphrgm could have contributed to the loss of the lung volume. This was evident only in the early period and was obvious in the transaxillary approach group.

Adult↗
PubMed1980

Atenolol in hypertension: a cardioselective drug.

The efficary of atenolol given one daily was assessed in 41 otherwise healthy hypertensive patients over a period of six months. Twelve patients whose blood pressure was not well-controlled on methyldopa and chlorthalidone and 11 patients who were treated previously with other beta-blockers all benefited from atenolol which appeared to be effective and well-tollerated. Ten patients complained of fatigue not necessarily related to a drop in blood pressure, and two of headache. Respiratory functions were assessed in a double blind trial on 30 patients. No significant changes in any of the expiratory flow rates were recorded after three months of continuous treatment with atenolol in either smokers or nonsmokers.

Adult↗
PubMed1978

Poisoning caused by inhalation of hydrogen chloride, phosphorus oxychloride, phosphorus pentachloride, oxalyl chloride, and oxalic acid.

Eleven people accidentally inhaled a significant amount of a gaseous mixture of hydrogen chloride, phosphorus oxychloride, phosphorus pentachloride, oxalyl chloride, and oxalic acid. Clinical observations and laboratory tests were recorded from the time of admission throughout hospitalization. The main abnormalities were found in the respiratory tract and consisted of clinical and physiologic evidence of obstruction of the airways, mild interstitial and alveolar edema, a defect in diffusion, and inequalities of ventilation and perfusion that produced hypoxemia. All of these cleared within a short time.

Accidents, Occupational↗
PubMed1978

Pulmonary function following the adult respiratory distress syndrome.

Fifteen patients (range of ages, 18 to 35 years) who survived an acute episole of the adult respiratory distress syndrome caused by mechanical or thermal injuries, sepsis, and shock were studied during 1 to 30 months after recovery. The patients had had no previous pulmonary diseases, and only two had been smokers. All of the patients were asymptomatic, and their chest x-ray films were normal on follow-up examination. Tests of pulmonary function revealed mild abnormalities which consisted of reduction of pulmonary volumes, decreased carbon monoxide diffusing capacity, and a mild increase of alveolar-arterial oxygen pressure gradients in the early stage ofter recovery. Improvement was noted after a few months, but eight patients still had mild reduction of pulmonary volume after one to two years. No correlation could be established between the severity of the adult respiratory distress syndrome, therapy with mechanically assisted ventilation, the duration of exposure to supplemental oxygen, the fractional concentration of oxygen in the inspired gas, and the degree of residual functional defect.

Adolescent↗
PubMed1977

Pulmonary functional abnormalities after upper dorsal sympathectomy.

Pulmonary function tests were performed in a group of 15 patients before and 1 to 3 months after upper dorsal sympathectomy. Significant decreases in all compartments of lung volume and maximal expiratory flows were found. Serial studies in 3 patients showed improvement after 6 to 8 months.

Adolescent↗
PubMedDate not supplied

Ventilatory response and pattern of breathing during hypercapnia.

In an attempt to narrow the definition of normal ventilatory response to hypercapnia (SVE), we studied 105 healthy Caucasians, aged from 18 to 80 years and living at sea level. The mean and SD of SVE were 2.18 +/- 0.77 1 X min-1 X mmHg-1 in males and 1.70 +/- 0.74 in females, narrower than the ranges previously reported. The 95% tolerance limits were 0.491-3.735 and 0.241-2.963 respectively. SVE was correlated with height, body surface area, static and dynamic lung volumes (p less than 0.01), age and weight (p less than 0.05). A prediction formula for SVE was derived on the basis of FEV1, which of the above parameters best correlated with SVE. The separate measurement of the tidal volume and frequency changes (SVT, Sf and SVT/Sf) showed that the SVT and SVT/Sf were significantly higher in males than in females even after adjustment for lung volume (p less than 0.01 and p less than 0.02 respectively), suggesting a different pattern of response to hypercapnia between the sexes.

Adolescent↗