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Biomedical subjects

M Mourot

Publications and source records attributed to M Mourot.

At least 19 recordsLinked to original sources

Early detection of hearing loss in children with cleft palates by brain-stem auditory response.

The hearing of 23 children with cleft palates was studied at an early age (before 12 months) and before pharyngoplasty using the electrophysiologic method of auditory brain-stem response. Nineteen children showed important degrees of conduction deafness of 50 or 60 dB. Results were compared with those obtained for a group of normal children tested under the same method before age 6 months. No hearing loss was observed in this group. It is concluded that hearing defects appear at an early age in children with cleft palates and are in direct relationship to the malformation. Hypotheses concerning the etiopathogeny of these hearing losses are proposed.

Brain Stem↗

[Separation of pygopagous Siamese twins].

The successful separation of pygopagous twins is described. The sacrum formed a common canal since S 1 to coccyx with two medullary cords side to side and diastematomyelia with, at this level, two dural sacks. In each baby there was small atrophy in one lower limb. There were two opposite vulvovaginal ducts and two recto-perineal fistules.

Anesthesia, General↗

[Epigastric congenital diverticulum of the right ventricle. Resection during the neonatal period (author's transl)].

The authors relate a neo-natal case of cardiac diverticulum of the right ventricle, reaching the epigastric area and associated with several connected malformations : partial pericardial agenesis, anterior diaphagmatic breach, diastasis of Musc. recti abdominis, skin aplasia in the epigastric area, and, moreover, dextrocardia with Fallot tetralogy. The diverticulum was successful resected in emergency.

Abnormalities, Multiple↗

Coating evolution with an implantable biological battery.

A cathode of smooth platinum in a right endoatrial position and an anode of Domal magnesium were used to construct a hybrid bioelectric battery designed to power a pacemaker. In use the cathode is gradually covered by a coating consisting of a crystalline layer and a layer of connective tissue. This coating is responsible for the system change in the reduction process at the cathode level: the transfer from an oxygen to a hydrogen system. This system change causes a voltage drop in the bioelectric battery. This paper deals with oxygen diffusion across the tissue layer, as well as with various spectral and chemical analyses. A high level of calcium and phosphorus in the different analyses carried out seems to show that the presence of these elements is related to the coating of the cathode. The effect on the formation of the coating of the position of the cathode is also discussed.

Animals↗

Design of experimentation with a platinum-magnesium bioelectric battery.

The utilization of metal electrodes in the fabrication of a bioelectric battery has been the subject of intensive study for several years. Up to this date, subcutaneous cathodes of black platinum or of silver-silver chloride have been used in conjunction with anodes of aluminum or zinc. The subcutaneous black platinum is not reliable as a function of time due to the growth of overlying heterogeneous tissues. The utilization of a smooth platinum cathode in the right endoauricular position allows good reliability with time, but does not allow using a large surface area. Furthermore we have a reduction of the H-+ ions and not of the oxygen. A pure Domal magnesium anode was utilized with this cathode, which seemed to be a good compromise between to battery's voltage, its lifetime, and its lack of toxicity to body tissues.

Animals↗

Long-term in vivo behavior of a platinum endoauricular-magnesium hybrid battery.

A hybrid bioelectric battery designed for pacemaker feeding was developed and implanted in 15 dogs for a period of 18 or more months. The smooth platinum cathode, set on an intra-cavitary pacing lead, is located in the bloodstream of the right auricle. The anode of pure (99.9 percent) Domal magnesium is placed in the subcutaneous tissue, which is then consumed by a uniform corrosion process. The theoretical consumption for a current output of 200 muA was evaluated according to Faraday's law at 7 g in 9 years; however, the real consumption, taking into account the corrosion phenomenon, is estimated at 14 g in 9 years. This histological tolerance to the magnesium is excellent. The fundamental characteristic of this platinum-magnesium battery is the great reproducibility of the output parameters (voltage, power) and the excellent stability with time, for any chosen platinum surface or load resistance. For an output current of 200 muA, the battery provides an available output power of 100 muW at a reproducible and stable voltage of 0.5 v. This stability is demonstrated in a long-term study on 15 beagles.

Animals↗