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M Mseddi

Publications and source records attributed to M Mseddi.

At least 19 recordsLinked to original sources
PubMed2007

[Subacute cutaneous lupus erythematosus in childhood: a case report].

Subacute cutaneous lupus erythematosus is extremely rare in childhood. We report the case of a 7 year-old girl who presented annular erythematous infiltrated lesions on sun exposed areas since the age of 2 months. Histopathologic examination showed orthohyperkeratosis, epidermal atrophy, widespread hydropic degeneration of epidermal basal cell layer, and a dermal lymphohistiocytic infiltrate. The lupus band test was negative. The immunological investigations (antinuclear antibodies) were negative. Treatment with antimalarials, topical steroids and sun protection allowed clearance of the cutaneous lesions. Lesions relapsed after antimalarials discontinuation and sun exposure. Four years later, at the age of 11, the antinuclear antibodies became positive. The diagnosis of subacute cutaneous lupus erythematosus is based on the clinical aspect of lesions, topography, histological finding, evolution and immunological profile of the patient.

Antimalarials↗
PubMed2006

[Radiographic diagnosis of dislocated inverted shoulder prosthesis: two cases of unrecognized dislocation].

Dislocation of inverted shoulder prostheses are rarely described in the literature. Diagnosis is relatively difficult as illustrated by two cases reported here which went unrecognized. The problem is the absence of any clear clinical sign of dislocation and the rather difficult interpretation of the radiographic images. We propose a method for analyzing the radiographic images which can be used to confirm the absence of dislocation on the AP view.

Diagnosis, Differential↗
PubMed2006

[Screw fracture after sliding hip screw fixation of an intertrochanteric fracture].

Although no cases have been reported to date, fracture of a sliding hip screw on a screw-plate fixation is a real entity since material watch registries have revealed two non-published cases. We report an illustrative case. A 67-year-old man was hospitalized for a right intertrochanteric fracture. The patient was treated with a sliding hip screw plate fixation (short cannon, 105 mm screw). On the eighth postoperative day, fracture impaction was present with complete loss of impaction reserve associated with secondary discrete divergence in the cannon-screw alignment. Weight-bearing was postponed until the 45th postoperative day. At three months, bone healing had not been achieved. A clear image was also visible at the plate end of the cannon. The patient complained of persistent pain but there were no signs of infection. At the fifth month, the patient fell from the standing position and standard x-rays visualized the nonunion of the intertrochanteric fracture plus a infratrochanteric diaphyseal fracture line in addition to a fracture of the sliding hip screw. The plate screws were intact. The patient underwent revision osteosynthesis with a Medoff plate. Fracture of a sliding hip screw is a rare event. In the present case, the mechanism involved an insufficient impaction reserve and use of a short cannon. Treatment requires extraction of the distal fragment of the screw and a new cemented osteosynthesis.

Aged↗
PubMed2006

[Biermer disease disclosed by mucous ulcerations].

Pernicious anemia rarely induces mucous membranes lesions, wich, exceptionally reveal the disease. We report a case of a 64-year-old man who presented a clinical history of recurrent painful ulcerations of the buccal, genital and ocular muosa. He also had peripheral sensory nerve impairement of the legs. The diagnosis of pernicious anemia was made after a 19 year course. Cobalamin supplementation induced an improvement of the mucous membrane lesions and of the anemia, but recurence occurred each time the treatment was stopped. Our observation is particular by the multiple mucous membrane involvement revealing pernicious anemia and by the ocular lesions which had never been previously reported.

Anemia, Pernicious↗
PubMed2006

[Profile of basal cell carcinomas of the scalp after radiotherapy for tinea capitis (about 63 cases)].

The induction of basal cell carcinoma (BCC) of the scalp by X-ray therapy for tinea capitis is well known. The aim of the study was to specify the epidemiological, clinical and histological characteristics of this disease. In a retrospective study, we collected data from the files of 63 patients, with a history of radiotherapy for tinea capitis, followed between January 1995 and December 2004. Fifty one men and 12 women with a total of 108 BCC of the scalp are reported (1.76 lesion per patient and 1.13 cm on average of diameter). The mean age at the occurrence of the BCC was 45.5 years. Thirty seven percent of BCC occurred on the occipital area; 28.7% were in the parietal site. The most frequent clinical aspect was the nodular BCC (51%) and the cicatricial BCC (35%). Histological study showed a nodular aspect in 74 % and pigmentation in 62% of cases. It is concluded that BCC of the scalp following X-ray therapy for tinea capitis have some clinical and histological particularities. It represents the most frequent tumour developing on irradiated scalp.

Adult↗
PubMed2005

[Radiotherapy-induced pemphigus: a case report].

A 61-year-old male patient suffering from squamous cell carcinoma of the lower lip developed pemphigus vulgaris two months after exposure to radiotherapy. Skin lesions were initially localised to the face and neck and later extended over other skin areas. The eruption are improved with glucosteroid therapy, which were stopped after six months. Pemphigus induced by radiotherapy is rare, latency before the onset of the vesiculobullous eruption is variable. Clinical, histological and immunological characteristics are similar to those of other types of pemphigus.

Adrenal Cortex Hormones↗
PubMed2005

[Glucantime injection: benefit versus toxicity].

UNLABELLED: Glucantime is the most common stibied derivative used to treat cutaneous leishmaniasis (CL) in Tunisia; however adverse effects have been reported. OBJECTIVES: This retrospective study deals with the various adverse of intramuscular glucantime used for CL. RESULTS: Nineteen patients (21%) receiving intramuscular Glucantime developed adverse effects. 8 male and 11 female patients, mean age 45, ranging from 8 to 84 years were affected. adverse effects were: fever (3), arthralgia and myalgia (4), nausea and vomiting (2), erythema nodosum (1), acute renal failure (3 including 1 lethal case), hepatic cytolysis (1), skin rash (4), and inflammation of the injection site (1). CONCLUSION: Adverse effects of intramuscular Glucantime were relatively frequent in our series. Arthralgia, myalgia, and skin rash were not severe and disappeared when the treatment was stopped. Stibiointoxication cases, mainly acute renal failure, were serious.

Aged↗
PubMed2005

[Ilizarov fixation of supramalleolar fractures].

PURPOSE OF THE STUDY: Supramalleolar fractures are generally considered to be a difficult surgical challenge because they occur in a area where the tibia lies superficially with a precarious blood supply to the skin, exposing to the risk of infection and necrosis after internal fixation. These fractures are also situated close to the tibiotalar joint making centromedullary nailing difficult, even with distal locking. The Ilizarov external fixator could be an attractive alternative in this indication. MATERIAL AND METHODS: We report a series of 17 supramalleolar fractures in 17 patients, 14 men and 3 women, treated with the Ilizarov external fixator between 1991 and 2001. Most were traffic accident victims and most had complex fractures resulting from high-energy trauma. There were many associated lesions. Fractures were open in ten patients. The Ilizarov fixator was used as the first intention treatment in seven patients and as a second line treatment in ten. The system allowed early weight bearing in all patients. RESULTS: Tolerance was generally good with a relatively low rate of superficial pin track infections (two cases). There was one case of osteitis which developed in a patient with an open fracture. There were no thromboembolic complications and no nerve involvement. Bone healing was achieved within three months in thirteen patients. There were three cases of late healing which were treated by the ascension technique using a cancellous graft and fibular osteotomy. The overall healing rate with this method was 94%. The one case of nonunion was successfully treated with an inter tibiofibular graft. The overall functional outcome was satisfactory in 76% of the patients, based on the Alho-Klemm criteria. Axial deformation predominated in the frontal plane: three patients had > 10 degrees varus in one case. DISCUSSION: These results could be improved by better operative technique. We advocate installing the patient in the supine position with transcalcaneal traction allowing good restitution of the leg axis. The assembly should be long, including the entire leg segment.

Adolescent↗
PubMed2005

[Hydatid cysts in muscles: eleven cases].

PURPOSE OF THE STUDY: Echinococciasis or hydatid disease is a cosmopolite antropozoonosis common to humans and several mammal species. The disease results from the development of the larval or hydatid form of the canine tenia (Echinococcus granulosis) in the organism. Hydatic cysts are uncommonly found in muscles, even in endemic zones. The purpose of this work was to describe the epidemiological, clinical and therapeutic aspects of hydatid cysts observed in muscles based on our clinical experience and data in the literature. MATERIAL AND METHODS: For this study, we collected data on eleven cases of hydatid cysts in muscles treated surgically at the Sousse University Hospital in Tunisia over a 17-year period from 1985 to 2002. We noted epidemiological, clinical, ultrasonographic and laboratory data which were analyzed to better detail the characteristic features of these localizations. RESULTS: Mean patient age was 30 years (range 7-50). All patients lived in rural areas where sheep raising and contact with dogs was common. Patients consulted for a tumefaction of the soft tissue which increased in volume progressively. The muscle focus was generally unique and primary. The proximal muscles of the limbs were involved predominantly. Ultrasonography was performed for nine patients and suggested the diagnosis in all cases. The typical feature was a liquid echostructure in an endemic context. Computed tomography was performed in four patients with deep cysts. Magnetic resonance imaging was not used. Surgical treatment was used in all cases with a pericystectomy in six. Early outcome was favorable excepting one case of suppuration of the resection zone observed in one woman. At 2.5 years, there have been no cases of local or distant recurrence. DISCUSSION: Several factors would explain the exceptional nature of muscle localizations of hydatid cysts: efficacy of the hepatic and pulmonary barriers, muscle environment not favorable for growth of hydatid larvae. The predominant localization in the proximal muscles of the lower limbs could be explained by the volume of the muscle mass and its rich blood supply. It is important to establish the diagnosis preoperatively in order limit the risk of anaphylactic shock or dissemination in the event of puncture or accidental opening of the cyst during resection. Ultrasonography is the diagnostic tool of choice. Surgery is required for treatment, ideally by en bloc total pericystectomy. Medical treatment with imidazoles has little efficacy for the treatment of muscular hydatid disease. CONCLUSION: Hydatid cysts are rarely found in muscles, even in highly endemic zones. The diagnosis must nevertheless be entertained depending on the clinical and endemic context. Ultrasonography, and accessorily magnetic resonance imaging, are the exploration tools of choice to confirm the diagnosis before surgery and avoid puncture. Exclusively surgical treatment is indicated, ideally for total pericystic resection without rupture.

Adolescent↗
PubMed2005

[Colostomy care].

Explore the source record for details and available documents.

Anal Canal↗
PubMed2005

[Bleomycin induced flagellate erythema].

Bleomycin is an antibiotic with antineoplastic pro prieties. It is used in the traitement of many syndromes. The cutaneous toxicity of bleomycin includes many alteration. We report a case of flagellate erythema following the administration of bleomycin in a 57-year-old women with Kaposi sarcoma. She developped linear lesions 6 days after the first dose of bleomycin. Flagellate erythema is a specific reaction to bleomycin therapy wich occurs in susceptible individuals independently of dose, route of administration and type of malignant disease treated. Its occurs in 10 to 35% of the treated patients.

Antimetabolites, Antineoplastic↗
PubMed2004

[Squamous cell carcinoma complicating an hereditary epidermolysis bullosa].

The dystrophic form of hereditary epidermolysis bullosa is associated with an increased frequency of squamous cell carcinoma. We report a new case. An 18-year-old patient, carrying a Hallopeau Siemens hereditary epidermolysis bullosa, presented a subcutaneous nodular lesion, for 1 year that ulcerated and budded with inguinal lymphadenopathy. The histological study led to the conclusion of a well differentiated squamous cell carcinoma. The patient was treated surgically. Tumor and metastatic lymph nodes were excised. A radiotherapy was decided but the postoperative course was fatal due to an infection and to a deterioration of her general condition. Squamous cell carcinoma frequently occurs on the cicatricial lesion of hereditary epidermolysis bullosa and usually affects males with recessive hereditary epidermolysis bullosa. Metastases are frequent, precocious and multiple. The treatment may be surgical. The particularities of our observation are the young age of patient and the localization.

Adolescent↗
PubMed2004

[Basal cell carcinoma of the scalp after radiation therapy for tinea capitis: 33 patients].

Occurrence of basal cell carcinoma (BCC) following radiotherapy for tinea capitis is well known. The aim of this study was to specify the clinical and histological features of these BCC seen in 33 patients (1995-2000). Twenty seven men and six women were diagnosed with BCC. The age of onset varied between 32 an 62 years. Radiotherapy was received between 5 and 17 years of age. The interval between irradiation and the onset of carcinoma varied between 21 and 51 years. Total number of lesions was 55. Forty percent of BCC occurred on the occipital area, the number varied from 1 to 5 and the size from 2 to 45 mm. Clinically, the nodular type was found in 51% of cases. Pigment was present in 64% of cases. Histological study showed a nodular aspect in 76% and pigmentation in 63% of cases. Nodular and pigmented type were the predominant BCC occurring after radiotherapy for tinea capitis in our series. In the literature, BCC are the most frequent carcinomas occurring after radiotherapy (70-100%). Pigmentation was not described in other series. The nodular histological form was the most frequent.

Adult↗
PubMed2003

[Pseudoxanthoma elasticum: 11 cases].

INTRODUCTION: Pseudoxanthoma elasticum is a congenital dystrophy of the connective tissue. Its clinical expression is cutaneous, ocular and cardiovascular. PATIENTS AND METHODS: The aim of our study was to specify the principle characteristics of this disease and to discuss the interest of various supplementary examinations in its diagnosis and control in a series of 11 patients. RESULTS: The study included 9 women and 2 men (sex ratio: 4.5). The mean age the onset of the symptoms was of 18 years. In 4 cases there was a family history of the disease. All the patients exhibited yellowish, pigskin, and papular lesions on the sides of the neck. The systematic ophthalmologic examination revealed angioid streaks in 7 cases and a pigskin aspect in 4 cases. The systematic cardiovascular and metabolic explorations revealed no abnormalities specific to pseudoxanthoma elasticum. Two cases of asymptomatic nephrocalcinosis were observed. DISCUSSION: In our patients, the disease was probably of autosomal recessive transmission. The predominance of women consulting for the disease would be explained by the esthetic damage. Diagnosis of pseudoxanthoma elasticum is based on clinical, histological and genetic criteria. Supplementary explorations are useful to confirm the diagnosis and also for the search to other, visceral, localizations. Such examinations vary depending on the teams, means and above all the evocative signs.

Adolescent↗