Implanon: when is the ideal time to insert?
The single rod implant was introduced to the UK in October 1999. This case illustrates a problem encountered with the timing of its insertion and highlights a possible note of caution.
Adult↗
Biomedical subjects
M Murnaghan
Publications and source records attributed to M Murnaghan.
Gynandroblastoma of ovary with juvenile granulosa cell component and heterologous intestinal type glands.
An ovarian gynandroblastoma in a 15-year-old girl is described. The predominant component was juvenile granulosa cell tumour. Areas of adult granulosa cell tumour and Sertoli cell elements were also present. Stromal theca and luteinised cells were identified. An additional histological finding was the presence of heterologous intestinal type glands. There was positive immunohistochemical staining of juvenile and adult granulosa cell areas with inhibin and MIC2 antibodies. Electronmicroscopy showed a close ultrastructural resemblance between tumour cells in granulosa and Sertoli cell areas, in spite of differences in architectural pattern, suggesting that both morphological components may derive from a single cell of origin. The tumour demonstrates a unique combination of elements which has not previously been described.
Adolescent↗
Extragenital müllerian carcinosarcoma arising from the peritoneum: report of two cases.
Müllerian carcinosarcomas occurring outside the female genital tract are extremely rare but occasionally they may arise from the peritoneum as part of the secondary müllerian system. This report describes two cases of extragenital müllerian carcinosarcoma with heterologous elements in the form of malignant cartilage. We wish to highlight the fact that these aggressive neoplasms may occasionally have a peritoneal origin, similar to primary peritoneal serous carcinomas.
Abdominal Pain↗