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Biomedical subjects

M Musicco

Publications and source records attributed to M Musicco.

74 records · Page 5Linked to original sources

A record card for the study of Neuronal Hyperexcitability Syndrome.

Neuronal Hyperexcitability Syndrome (NHS) is a nosographic picture which is difficult to diagnose, due to the lack of specific standard diagnostic criteria. With slightly varying symptoms the syndrome has also been defined as Spasmophilia and Hyperventilation Syndrome. It is difficult to distinguish between NHS and panic attack disorder as there is considerable overlapping of symptomatology. We aimed to propose a standardized card which will be the first step toward a valid diagnosis of this complex neuropsychiatric problem. This card, which will be validated and of which the reliability will be evaluated, is proposed for clinical and research purposes. The card is made up of 6 parts (113 items) covering: personal data, pharmacological treatment, persistent diseases and related therapies, symptomatology trend, factors interfering with calcium-magnesium homeostasis and symptom assessment. The symptom assessment section is essential for the checking of diagnostic criteria and the earlier sections are important for the monitoring of other factors which can cause symptoms able to simulate NHS. There are also two special sections for recording laboratory tests and patients' psychic profiles.

Anti-Anxiety Agents↗

Mortality studies in the clarification of gene-environment interactions.

In this paper we review some theories about the process of senescence and death, in particular the theory of accumulation of mutations and the theory of antagonistic pleiotropism. These theories are reviewed in the light of existing scientific evidence, with particular reference to that which points to the possible role of interactions between genes and environment. We conclude that mortality studies, particularly on migrant populations may be an important tool for clarifying this major issue.

Age Distribution↗