[Vitamin B1 and magnesium in the erythrocytes of patients in a long-term dialysis program].
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Biomedical subjects
Publications and source records attributed to M Mydlík.
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Urinary excretion of vitamin C was investigated in 44 patients with chronic renal diseases and in 25 patients after renal transplantation with various mean glomerular filtration rates. In both groups a hyperbolic relationship was observed between FE vitamin C and CCr. In addition, direct relationships were found between FE vitamin C and FE Na, FEK and FE H2O in both groups. Various chronic renal diseases and treatments had no influence on the investigated relationships. In 16 healthy subjects urinary excretion of sodium during maximal water diuresis did not increase but urinary excretion of vitamin C significantly increased. In 10 patients in the polyuric stage of chronic renal failure without dialysis treatment during Giordano-Giovanetti-Maggiora diet with addition of sodium chloride the urinary excretion of sodium increased but that of vitamin C was not influenced. The results obtained for the biochemical parameters tested suggest that the urinary excretion of vitamin C depends on the urinary excretion of water.
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The authors assessed vitamin A, and its protein carriers vitamins C and E in serum and dialysis fluid of 10 patients with chronic renal failure during 6-12 months of continuous ambulatory peritoneal dialysis. Vitamin A and its protein carriers and serum vitamin E were elevated throughout the long-term investigation of continuous ambulatory peritoneal dialysis despite the fact that vitamin A and its protein carriers have a relatively great peritoneal transfer and loss into the dialysis fluid. The oral dose of 200 mg of vitamin C per day, despite the great peritoneal transfer and loss into the dialysis fluid, prevented the development of hypovitaminosis C. Assessment of vitamins B1, B2 and B6 revealed that the supplementation with these vitamins is adequate for patients during continuous ambulatory peritoneal dialysis.
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