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Biomedical subjects

M Myhre

Publications and source records attributed to M Myhre.

4 recordsLinked to original sources

Nasopharyngeal angiofibroma treated in 1841 by maxillectomy.

One of the earliest recorded maxillectomy procedures was carried out on a 21-year-old male in University College Hospital, London, in 1841 by Mr. Liston. The case report and operative procedure are given. The gross, radiographic and microscopic features of the resection specimen, which was preserved until the present as a museum specimen, are provided. The tumor is an advanced nasopharyngeal angiofibroma and demonstrates the mode of spread of this lesion when treatment is delayed.

Histiocytoma, Benign Fibrous↗

Clear cell mesothelioma.

A clear cell form of epithelial mesothelioma is described. This variant does not appear to have been previously described, and it merits recognition since it is readily confused by routine light microscopy with other tumors that involve the pleura, including metastatic carcinomas composed predominantly of cells with optically clear cytoplasm. Ultrastructural and immunohistochemical studies were helpful in reaching the diagnosis in this case, and electron microscopy is particularly recommended to investigate the differential diagnosis of unusual pleural tumors.

Aged↗

Plasmacytoid transitional cell carcinoma. Report of a case with initial presentation mimicking multiple myeloma.

The case of a 63-year-old man with a previously undescribed morphologic variant of transitional cell carcinoma of the urinary bladder is reported. The patient initially presented with multiple lytic bony metastases of the ribs and skull. Aspiration biopsy of one of the lytic lesions of the skull showed tumor cells with a striking plasmacytoid appearance, similar to the plasma cells seen in myeloma, leading to an initial observer's diagnosis of multiple myeloma. Subsequently, a bladder tumor with the same cytomorphology was found; immunohistochemical and ultra structural studies performed on the aspirated material and on the bladder biopsy specimen clearly established the epithelial nature of this neoplasm.

Biopsy, Needle↗