Biomedical subjects

M N Gunraj

Publications and source records attributed to M N Gunraj.

4 recordsLinked to original sources

PubMed1999

Dental root resorption.

This article presents a review of physiologic mechanisms involved in various types of root resorption that may be encountered clinically. Included is a brief overview of suggested homeostatic mechanisms of the periodontal ligament and the role of the intermediate cementum in inhibiting root resorption. Root resorption (surface, inflammatory, and replacement) associated with traumatic injuries is discussed, with emphasis on etiology and the ability to provide treatment. The final discussion relates to other types of resorption, based on a classification of internal, cervical, and external resorption associated with periradicular pathosis and resulting from pressure in the periodontal ligament.

Humans↗

PubMed1990

Decompression of a large periapical lesion utilizing an improved drainage device.

A decompression device constructed of plastic intravenous tubing attached to an acrylic base and ligated into position with orthodontic ligature wire was used to successfully reduce a large periapical lesion in the anterior mandible. Guidelines for this treatment approach are presented.

Adult↗

PubMed1990

Assessment of endodontically treated teeth for restorative procedures.

This article describes a case report in which cementation of cast posts and cores in endodontically treated upper central incisors resulted in extrusion of zinc phosphate cement into the periapical tissues. This case demonstrates the necessity for careful evaluation of existing endodontic therapy before proceeding with the restorative phase of treatment. Some primary indications for endodontic re-treatment are suggested.

Adult↗

PubMed1987

Immunocompetent cells in the normal dental pulp.

The existence and location of various immunocompetent cells in the human dental pulp were investigated. Pulp tissue for analysis was obtained both from clinically intact pre-molars and from third molars without restorations or caries. Frozen and acetone-fixed pulp tissue sections were subjected to indirect immunohistochemistry with monoclonal antibodies to the following cell types: all peripheral T cells, helper/inducer T cells, cytotoxic/suppressor T cells, macrophages, B cells, and Class II antigen-expressing cells. Dendritic cells expressing Class II antigens (HLA-DR, -DQ), indicating a capacity for presentation of antigen to T helper cells, were seen in the odontoblastic layer as well as in the central portions of the pulp tissue. T lymphocytes, divided into helper/inducer and cytotoxic/suppressor cells, were observed in all pulp specimens. B cells were not seen in any of the pulp samples examined. The data demonstrate that the human dental pulp is equipped with immunocompetent cells essential for the initiation of immunological responses.

Adolescent↗