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Biomedical subjects

M N Lloyd

Publications and source records attributed to M N Lloyd.

4 recordsLinked to original sources
PubMed1994

Post-traumatic cerebrospinal fluid rhinorrhoea: modern high-definition computed tomography is all that is required for the effective demonstration of the site of leakage.

Accurate definition of the site of cerebrospinal fluid (CSF) leakage is essential for the successful surgical management of CSF rhinorrhoea and associated recurrent meningitis. Previous attempts to image the sites of leakage, including conventional computed tomography (CT) and cisternography using either iodine-containing contrast media or radionuclides, have given disappointing results. A dedicated high-resolution computed tomographic (CT) technique combining fine slices in two planes with a bone algorithm for data manipulation is described and the results in 15 consecutive patients are recorded. This technique promises to render all other diagnostic methods obsolete.

Adult↗
PubMed1990

Pre-operative localisation in primary hyperparathyroidism.

One hundred and seventy-three patients operated on for primary hyperparathyroidism over a four year period by one experienced surgeon are reviewed. An overall success rate of 98.8% was achieved with information from pre-operative localisation using ultrasound and parathyroid venography with sampling. Parathyroid ultrasound was heavily dependent on the experience of the operator. An experienced ultrasonologist detected 63% of solitary adenomas and correctly localised the site of 82%. Glands were not detected if they were of small size or in an inaccessible site. He identified all those enlarged glands over 0.36 grams in weight that were lying in the usual site. In contrast, inexperienced ultrasonologists had a detection rate of 20%. Parathyroid venography with sampling detected a single site of excess hormone production in the neck of 79% of patients with a single adenoma, and correctly localised the site in 75% of these. The side was correctly predicted for 63% of glands, the level was correctly predicted for 56% and both side and level localisations were correct in 44%. Multi-gland disease was correctly suggested by the experienced ultrasonologist in 56% of cases and by parathyroid venography with sampling in 31% cases.

Adenoma↗