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Biomedical subjects

M N Pamir

Publications and source records attributed to M N Pamir.

52 records · Page 3Linked to original sources
PubMed1992

The aid of computerized tomography in hemifacial spasm.

Although the physiopathological mechanisms causing hemifacial spasm are not clearly understood, it is generally accepted that the causative factor is compression of the facial nerve at its root exit zone. In this paper we present seven cases of hemifacial spasm which were studied by dynamic CT scanning in the preoperative period, and treated with microvascular decompression. We suggest that CT scanning has considerable diagnostic value in disclosing the asymmetrical vascular formation causing root exit zone compression and that microvascular decompression should be the treatment of choice in this condition.

Adult↗
PubMed1990

"Upside down" reversal of vision after third ventriculostomy.

Upside-down reversal of vision is a very rare kind of visual illusion characterized by the upside-down appearance of all objects within the visual field. Only seven cases have been reported since its description. In this paper, we report a case of upside-down reversal of vision, which occurred following a third ventriculostomy operation for hydrocephalus. This is the first case reported in the literature after a surgical intervention.

Adolescent↗
PubMed1988

Fetal pituitary transplants into the hypothalamic area of hypophysectomized rats.

The pituitary tissue, when transplanted to extracerebral sites other than the normal anatomic position, fails to perform its secretory function properly. Several works on experimental intracerebral pituitary transplantation have shown that the transplanted tissue has been able to survive histologically. In this study, fetal pituitary tissue was implanted into the anterior hypothalamic area of the hypophysectomized rat by stereotactic methods. Electron-microscopic examination and hormonal blood levels demonstrated that ectopic pituitary tissue was able to survive to establish the correct anatomic relationship and thus perform secretory functions when transplanted intracerebrally.

Animals↗
PubMed1987

Spinal meningiomas.

Between the years of 1970-1982 29 spinal meningioma cases were operated on; 22 cases (76%) were female and 7 (24%) were male. The youngest patient was 16, and the oldest was 68 years old. On neurological examination, patients had neurological deficits in varying degrees. Diagnosis were done by myelography in all cases. Laminectomy was performed in all cases. 34.4% of cases were situated in cervical region and 65.6% were in thoracic region. 14% of the tumours were located extradurally and 68% were intradural. Multiple spinal meningioma was seen in only one case. One case died after operation; the mortality rate is 4%. 22 cases came for follow-up examination, 86.5% of them were in excellent or good condition. Only three cases showed no improvement.

Adolescent↗
PubMed1985

[Primary carcinoma of the choroid plexus. 2 case reports and review of the literature].

Primary Carcinomas of Choroid Plexus are seen rarely. In previous literature there were 37 cases which were reported according to Lewis and Russel-Rubinstein malignancy criterias. In this article, we describe 5 years old boy and 1.5 year old girl who suffered from cerebellar ataxia and intracranial pressure increase syndrome. In case 1, the tumor of the fourth ventricle was diagnosed by brachial angiography and ventriculography. In case 2, the diagnosis was established by CT scan. In case 1, the patient died during the postoperative course. In case 2, the postoperative time was unremarkable. A radiotherapy of 3 000 rads was applied to the posterior fossa. One year later, the patient had only mild ataxia.

Adolescent↗
PubMed1984

Intracranial solitary chondroma. Case report.

A patient is described who had a solitary left frontal intracranial chondroma originating from the falx cerebri. The tumor was totally removed. The diagnostic value of computerized tomography and the surgical findings in this rare pathological condition are discussed.

Adult↗
PubMed1984

[Intracranial ependymomas. Study of 81 cases and comparison with the literature].

For ten-years of period, between 1973-1982, 81 cases with intracranial ependymoma have been operated in H.U.T.F. Neurosurgery Department. Supratentorial localisation have been found in 24 cases (30%), and infratentorial in 57 (70%). 80% of the patients in supratentorial group and 91% in infratentorial group were under the age 20. In supratentorial group 79% were in paraventricular localisation, and 21% were intraventricular. In infratentorial group 70% of the cases were localised within the IV. ventricle, 20% in province of the tentorial roof, 5% in the lateral recessus and 5% into cerebellum. The 40 patients who were followed up were rated according to the localisation and the grades of the tumors, the type of the surgical intervention and chemotherapy with respect to the postoperative survival. As a result only the total resection of the tumor was found to be significant.

Adolescent↗
PubMed1984

[Papilloma of the choroid plexus of the 3d ventricle. Report of a case and review of the literature].

It's rare for CPP to fill the III ventricule. Up to date, 24 cases surgically removed have been reported. In this report, we present a 1,5 year old boy who administered because of severe cachexia and reactive coma. Ct scan revealed dilatation in lateral ventricles and a mass totally filling the III ventricle. The mass has been totally excised through foramen Monro by right frontoparietal craniotomy and transcortical transventricular surgical approach. While a post-operative recovery was being observed, the patient died in the 30 the day because of bronchopneumonia. The treatment of III ventricle CPP as all the other CPP, must be total resection. For this reason, preoperative CT scan carries a great value about giving information of the nature of the tumor.

Cerebral Ventricle Neoplasms↗
PubMed1984

Spinal hydatid cysts.

Eleven cases of spinal hydatid cyst are reported. The patients were admitted with symptoms of compression of the spinal cord. The cysts were localized epidurally in 10 patients and intradurally but extramedullarily in one, and were confirmed histopatholgically after surgical intervention. The results are compared with those reported in the literature. Six of the patients were female and five were male. Their ages ranged from 10 to 65 years. All of the patients were treated surgically, with an incidence of cyst recurrence of 18% and no mortality. Mebendazole (Vermox) was given to two of the patients after their operations.

Adolescent↗
PubMed1981

Papilledema in Behçet's syndrome.

Six patients with Behçet's syndrome (five male, one female) had intracranial hypertension diagnosed by elevated CSF pressure in the presence of normal or small ventricles. All six patients had headaches and papilledema. Histories included oral ulcers in 5 patients, genital ulcers in 3, uveitis in 1, arthralgia in 4, and thrombophlebitis in 3. One patient had obstruction of the superior vena cava. A filling defect in the superior sagittal sinus was shown in two patients by carotid angiography, and cerebral circulation time was prolonged in one patient. Papilledema and intracranial hypertension as a result of cerebral vein thrombosis can be initial manifestations of Behçet's syndrome. This has not been a well-recognized feature of the syndrome.

Adolescent↗
PubMedDate not supplied

CT myelography in communicating syringomyelia.

Although the etiology of syringomyelia is not clearly understood, many surgical methods have been proposed for its treatment. One widely used technique in cases of communicating syringomyelia is that of posterior fossa decompression and plugging of the obex (Gardner's Operation). In this paper we present five cases of syringomyelia which were investigated using detailed myelo-computerized tomographic techniques, of which two appeared to be communicating syringomyelia and which were treated by posterior fossa decompression and obex plugging. We also discuss the place of computed tomography in the differential diagnosis of communicating syringomyelia.

Adolescent↗
PubMedDate not supplied

Gliosarcoma associated with neurofibromatosis type I: a case report.

Neurofibromatosis type I (NF I) is the most common hereditary syndrome predisposing to neoplasia. We report the third case in the literature, documenting the combination of gliosarcoma with NF I. The patient's son was known at our center because of a history of pleomorphic xanthoastrocytoma (PXA) with NF I. A 48-year-old man who had a number of café-au-lait spots with neurofibroma since birth presented with severe headache. Neuroradiological studies revealed a cystic tumor of the right temporal lobe of high grade nature. Surgical excision was performed and the tumor was found to be located on the surface of the temporoparietal area with cystic formation and vascular and infiltrative features. Postoperative MRI Key words: gliosarcoma, neurofibromatosis I, temporal lobe. showed no detectable contrast enhancing tissue. Immunohistochemical examination evidenced the characteristics of typical gliosarcoma. The patient received radiation therapy but five months following surgery recurrence of the tumor was diagnosed. Reoperation was performed and histopathological studies confirmed the diagnosis of gliosarcoma. We believe that the neurofibromatosis was inherited by the son with PXA from the father with gliosarcoma. The rarity of the combined occurrence of gliosarcoma and NF I, in addition to this uncommon family history, makes this case remarkable. Our findings suggest that NF I is a multifaceted disease associated with benign as well as malignant astrocytic tumors.

Brain Neoplasms↗
PubMedDate not supplied

Tumor in tumor: metastasis of breast carcinoma to intracranial meningioma.

This report presents magnetic resonance imaging (MRI) findings of a breast carcinoma metastasis in an intracranial meningioma with correlated pathological findings. MRI showed multiple foci of intense enhancement with hypointense surrounding areas. The described foci appeared to be metastatic disease from the patient's known breast carcinoma. In addition, this is the first study reported in the literature to have investigated the expression of a possibly common carcinogenic molecule in breast carcinoma metastatic to a coexisting meningioma: overexpressed c-myc oncogene was found both in the breast carcinoma compartment and in the meningioma component of the tumor.

Breast Neoplasms↗
PubMedDate not supplied

Cerebral echinococcosis multilocularis. Case report.

Cerebral occurrence of Echinococcus multilocularis is very rare and there is no widely accepted therapeutical method. In this report we present a case with an intracranial mass lesion and a palpable hepatic mass, which appeared to be due to Echinococcus multilocularis in the histopathological examination.

Adult↗
PubMedDate not supplied

Subependymal giant cell astrocytomas in tuberous sclerosis.

Two cases of tuberous sclerosis with subependymal giant cell astrocytoma are presented. This rare autosomal dominant disorder was also detected in family members of the patients who had never had any symptoms of cerebral involvement. Both patients underwent surgery because of signs of increased intracranial pressure.

Adult↗