PubMed Health⌕ Search

Biomedical subjects

M N Puzin

Publications and source records attributed to M N Puzin.

At least 19 recordsLinked to original sources
PubMed1992

[Personality characteristics of patients with prosopalgias].

The MMPI test, Hornblow and Kidson's visual-analog anxiety scale and two types of the painful "questionnaires" suggested by the authors were used to examine the status of emotional personality sphere in 61 patients with prosopalgias due to typical trigeminal neuralgia (n = 39), dental plexalgia (n = 13) and pulpitis (n = 9). It has been revealed that patients with typical trigeminal neuralgia demonstrate the predominance of the depressive syndrome, whereas dental plexalgia is mostly characterized by anxiety. Analysis of the semantic tests is very instrumental in helping the physician to deepen the idea of the structure of subjective sensations in facial pain. Meanwhile the indicators of the "daily pain scale" promote administration of the drugs from the standpoint of chronotherapy.

Adult↗
PubMed1990

[Cluster headache].

Cluster headache is a disputable and ill-defined problem of current neurology. The authors review data available on etiology, mechanisms of pathogenesis and therapy with special emphasis on biochemical and immunological disturbances; discuss nosology of the disease in the light of newly obtained evidence on its immunological aspects. An overall table of clinically justified treatments is presented.

Adult↗
PubMed1990

[Immunologic status in autonomic prosopalgias].

The authors describe the results of immunological examination of patients suffering from vegetative prosopalgias. A study was made of the initial status of immunity and of its dynamics after treatment. The majority of patients manifested an increase of immunoglobulin A concentration and activation of local humoral immunity. The treatment brought about a reduction of immunoglobulin A concentration in blood serum.

Adult↗
PubMed1990

[Electroconvulsive therapy of trigeminal neuralgia].

The authors describe a new method of the treatment of patients with trigeminal neuralgias using electroconvulsive therapy. The method is based on the increase of beta-endorphin concentration as a result of electroconvulsive treatment. The treatment of 12 patients in accordance with the suggested method provided beneficial results and significant enhancement of the efficacy of therapy as compared to patients undergoing conventional treatment.

Adult↗
PubMed1990

[Immunologic and biochemical changes in patients with cranio-facial pain].

The authors provide the results of an analysis of the interrelation between the immunologic and biochemical parameters in 6 groups of patients suffering from facial pains or headaches (a total of 153 patients). Significant correlations were revealed in the patients' groups with trigeminal neuralgia and periodic migrainous Horton's neuralgia. The main attention was concentrated on the following parameters: IgA in the serum, secretory IgA in the patients' saliva, % CD4 of lymphocytes and histamine concentration in the peripheral blood, concentration of beta-endorphin in the plasma, catecholamine content in the urine.

Catecholamines↗
PubMed1990

[Study of secretion and blood protein transport of testosterone in patients with neurogenic facial diseases].

Altogether 85 patients with the painful syndromes in the facial and head areas were examined for secretion and transport of testosterone, the main androgen occurring in the body of adult man, by the blood proteins globulin- and albumin-binding sex steroids. All the women examined were in the menopause. The majority of the patients manifested hyperandrogenemia: a decrease in the concentration of sex steroids-binding globulin, rise of total testosterone and its free fraction in the blood serum as well as increase of the index of free androgens. Approaches to the correction of the revealed abnormalities and the role played by those abnormalities in the pathogenesis of the above-indicated diseases are under discussion.

Adult↗
PubMed1990

[New aspects of pathogenesis and treatment of neurostomatological diseases with the predominant pain syndrome].

Somatosensory evoked potentials, biochemical, immunological, pharmacokinetic and psychological research methods were used to examine 308 patients suffering from neuralgia of the trigeminal and glossopharyngeal nerves, neuropathy of the trigeminal nerve, neuralgias of the face and painful dysfunction of the temporomandibular articulation. New mechanisms of the pathogenesis of the diseases indicated were revealed. That made it possible to improve and devise new treatment methods.

Combined Modality Therapy↗
PubMed1989

[The level of serotonin in the blood of patients with trigeminal neuralgia].

Serotonin levels in patients with trigeminal neuralgia were studied according to the pain syndrome. The results evidence normalization of the blood serotonin concentration, possibly due to a favourable effect of therapy on serotonin metabolism, which reflects activation and optimization of the gate system for pain control.

Adult↗
PubMed1989

[Beta-endorphin levels in patients with pain syndromes in the areas of the face and head].

Blood plasma beta-endorphin concentrations were measured in 87 patients with various facial and head pain syndromes: trigeminal neuralgia or neuropathy Horner syndrome and migraine, facial autonomic pains. beta-endorphin concentrations were measured before and after treatment. In the groups under investigation, the neuropeptide showed opposite changes in plasma levels after the therapy depending on the type of the syndrome.

Adult↗
PubMed1989

[Immunologic aspects of migraine headaches and autonomic prosopalgias].

The paper presents the results of an immunological screening of patients with facial vegetative neuralgia, Horton's syndrome, and migraines prior to and following therapy. The patients with migraines were found to have an activated local humoral immunity. Those from all the groups showed lower serum immunoglobulin A concentrations after therapeutic interventions.

Adult↗
PubMed1989

[Odontogenic neuropathy of the trigeminal nerve].

The paper is concerned with the problems of the etiology, pathogenesis, clinical picture and methods of the treatment of odontogenic neuropathies of the trigeminal nerve. The clinical manifestations of odontogenic neuropathies of the trigeminal nerve are described in detail. The data on the preclinical methods of examination are provided as are pathogenetically based schemes of the treatment for odontogenic neuropathies of the trigeminal nerves.

Adult↗
PubMed1989

[Immunological status of patients with painful syndromes in the face and head].

As many as 145 patients with painful syndromes in the face and head underwent immunologic examination. They manifested certain changes in cellular and humoral immunity. An increase in the content of secretory IgA in the saliva and in the serum and a decrease of the concentration of IgM and IgG in the serum were detected in the majority of patients. In patients with NTN of mainly peripheral genesis and with Horton's syndrome, the concentration of IgE in the serum was significantly (P less than 0.01) elevated. The changes in the immunologic status, seen in patients after the treatment are discussed.

Adult↗