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Biomedical subjects

M N Titov

Publications and source records attributed to M N Titov.

5 recordsLinked to original sources

Effect of low-energy laser irradiation on the area of experimental myocardial infarction, lipid peroxidation, and hemoglobin affinity for oxygen.

The mechanism of antiischemic effect of low-energy laser radiation was studied in rats with experimental myocardial infarction taking into consideration the effect of laser on hemoglobin affinity for oxygen and intensity of lipid peroxidation. Low-energy laser irradiation for 15 min in vitro decreased the area of myocardial infarction, slightly reduced hemoglobin affinity for oxygen, and inhibited lipid peroxidation. Short-term low-energy laser irradiation did not reduce the area of necrosis, initiated lipid peroxidation, and increased superoxide dismutase activity.

Animals↗

[Cytological indices as criteria for assessing periodontal status].

The authors define the complex of criteria for analysis of cytograms of gingival impressions in health and periodontal diseases. Such criteria are needed for objective diagnosis and monitoring of periodontal status over the course of treatment. All the cellular elements were taken account of: different types of epithelial cells, including those with signs of cytopathology and bacterial contamination, connective tissue cells, mononuclears, leukocytes, and fibroblasts. The cytological picture correlated with the status of periodontium and forms and severity of pathological processes developing in it.

Humans↗

[The biomedical efficacy of 2 variants of polyacrylamide gel- and hydroxyapatite-based composite materials in the plastic repair of bone defects (experimental morphological research)].

Tissue status at the site of experimental bone defects filled by two compositions based on polyacrylamide gel and hydroxyapatite with (experimental group) and without (controls) lysozyme was studied in rats by the histomorphological method. "Negative" symptoms, such as inflammation, formation of osteocyte-free bone at the interface of the defect, and reduction of red bone marrow were more manifest in the controls than in animals treated with lysozyme. In the test group substitution of composite material for connective tissue structures and bone reparation were much more active and rapid than in the controls. Inflammation and dystrophic changes at the interface of defects were less pronounced and gradually resolved.

Acrylic Resins↗

[An experimental trial of a hydroxyapatite-based root paste].

Hydroxyapatite-based radicular paste was tried in 12 dogs with experimental chronic periodontitis. Hydroxyapatite, zinc-eugenol, and resorcin-formal pastes were compared. The periodontal status was assessed by morphometric methods. Hydroxyapatite-based radicular paste was found to be the most effective means of treating experimental chronic periodontitis. In control groups the therapeutic effect was either null or minimal.

Animals↗