[On the mechanism of radiosensitization by moniodoacetic acid].
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Biomedical subjects
Publications and source records attributed to M Năstase.
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Two cases are presented, of hemolytic jaundice, determined by rifampicin. The first occured in a woman in whom treatment was started again after an interruption of 6 months and the second in a man undergoing intermittent treatment that had been tolerated very well for 3 months. Following the extension of the application of rifampicin in intermittent treatment might occur more frequently. Posology apparently has a major role and some precautions are to be taken.
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The operational and technical efficiencies were evaluated, of the initial, intermittently administered chemotherapy, supervised and integrated by the general medical network. The treatment was applied in 160 patients detected in 53 rural medical districts. It was noted that under the operational aspect the treatment was applied in 100% of the eligible patients, and administration of all the necessary doses was achieved in 91,6% of the patients. Bacteriological negativation by the direct examination was obtained after three months and negative cultures were obtained in 93,3% of the patients at three months and in 97,4% of all patients after 9 and 12 months. Closure (filling) of the cavities was obtained in 75,4% of the cases after three months of treatment, and in 87,7% of all cases after 9 and 12 months. Finally the technical efficiency was completed by an assessment of the socio-professional recovery, that was achieved in 91,8% of the cases.
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