Biomedical subjects

M Nakládalová

Publications and source records attributed to M Nakládalová.

5 recordsLinked to original sources

PubMed2006

[The influence of targeted intervention on the incidence of risk factors of cardiovascular diseases at medical staff].

INTRODUCTION: The work addresses the targeted intervention of cardiovascular diseases at medical staff. SET AND METHODICS: During 2002-2004 years, within the scope of preventive examination, there was made targeted prevention of risk factors of cardiovascular diseases (CVD) at the big hospital employees at the Centre of preventive care of employees and in the department of preventive cardiology of Ist Internal Clinic of LF UP and FN Olomouc. According to the effective tables, there was stated a CVD risk of these employees. The employees received a personal individual letter which informed them of the level of CVD risk and proposed a targeted intervention of risk factors. The part of the set--427 employees of the average age of 38.93 years (SD 11.39), 69 men (M) of the average age of 40 years (SD 12.47) and 358 women (F) of the average age of 38.7 years (SD 11.18) was examined another time during 2004-2005 years. The methodics of second examination was the same as at the first examination, only the questionnaire was complemented by the questions related to the knowledge of the CVD risk stated at previous examination. RESULTS: There occurred statistically significant decrease of LDL cholesterol in the set (from 2.87 mmol/l to 1.23 mmol/l, p < 0.0001) and BMI decrease (from 24.35 to 24.16, p < 0.05) and at the same time statistically significant increase of total cholesterol (from 5.09 mmol/l to 5.27 mmol/l, p < 0.05) and triglycerides (from 1.27 mmol/l to 3.01 mmol/l, p < 0.0001). There was no significant change in other RFs (BP, WHR, HDL cholesterol, moving activity). The influence on RF of smoking was statistically significant (23 employees quitted smoking, 10 employees started, p < 0.05). 53 F (14.80%) and 3 M (4.34%) know their cardiovascular risk, 235 F (65.64%) and 53 M (76.81%) do not know their cardiovascular risk. CONCLUSION: The work approved the influence of targeted intervention on the incidence of cardiovascular diseases risk factors and at the same time low level of knowledge of one's own individual risk, despite of targeted intervention.

Adult↗

PubMed2000

Byssinosis.

Byssinosis as a nonspecific chronic respiratory disease in textile workers exposed to cotton, flax, jute, hemp and sisal is described. Opinions about aetiopathogenesis are presented. The following chapters are focused on clinical symptoms and functional lung changes. Classification of the disease is described afterwards. Finally, the necessity of medical and technical measures to prevent the development of this disease in textile workers is emphasised.

Byssinosis↗

PubMed1999

Alternative treatment of the carpal tunnel syndrome.

Carpal tunnel syndrome (CTS) is a painful disease of the wrist which is usually treated with corticoids locally or surgically. In this study combined infusion therapy with procain, pentoxyphyllin and magnesium sulphuricum in patients with CTS was evaluated retrospectively. 101 manually working patients (65 male, 36 female) aged 42.8 +/- 8.6 years, initially examined at our department to assess professional origin of the disease and who had abnormal conduction to the distal section of median nerve on electromyography (EMG), were entrolled. The group of patients was heterogenous etiologically. 41% of patients were found to be exposed to overlimit vibrations, while 21% of patients were exposed to overload of upper extremities and 16% patients to both the risks. The professional hazard was not proved in 23% of patients. In these patients 166 CTS were diagnosed of which 144 improved after the treatment, while the condition remained unchanged in 11 and even worsened in another 11 cases. Using the clinical and EMG criteria the findings were divided to mild, moderate and severe CTS. 77 mild CTS improved by 61% in average, 63 moderate CTS were improved by 47% and 26 of severe CTS improved by 50%. There was no association between the treatment outcome and sex, age or severity of symptoms. Patients with unfavourite outcome and the possible causes of treatment failure are discussed in detail.

Adult↗

PubMed1995

Bone mineralization changes in saw operators.

In vibration disease the impact on bone and joint systems is considered to be the least frequent one. It includes a degenerative component, rare necrotic alteration and osteoporosis, together with cystic alterations, in the carpal bones. The authors concentrated only on osteoporosis in the proximal parts of upper extremities. They evaluated by X-rays of the thorax the extent of mineralization and, consequently, the osteoporosis of the clavicles. For that purpose they used the corticodiaphyseal Barnett-Nordin index (BNI). In a group of 107 chain saw operators whose both upper extremities had been exposed to the impact of vibration exceeding the threshold limit while operating a chain saw, a statistically significant difference was established in the mineralization of clavicles. These findings contrasted with a control group of 107 healthy males who had never worked with vibrating equipment. The authors did not establish a statistically significant dependence of these changes on simultaneously diagnosed traumatic vasoneurosis and neuropathy. After the risk elimination of vibration the value of the BNI indicates the dynamics and the reversibility of the parameter under observation. These findings suggest that osteoporosis due to the impact of vibrations is by no means a rare phenomenon. It does not affect only the distal parts of the upper extremities. Similarly as angiological and neurological changes, osteoporosis tends towards spontaneous adjustment, once the risk of vibrations has been eliminated.

Adult↗

PubMed1995

State of health in dental technicians with regard to vibration exposure and overload of upper extremities.

The authors examined 120 dental technicians, 111 women, 9 men, of mean age 44.8 years, mean duration of exposure 24.9 years. Cold water test, plethysmographic investigation, and EMG (in indicated persons), X-ray, neurological and orthopedic examinations were performed. Combination of exposure to vibration above the limit value, with overload of upper extremities, was proved by hygienic measurement. The most frequent subjective complaints included vertebral complaints (52.5%), paresthesiae in the hand fingers (47.4%) and pain in the joints of upper extremities (elbow 26.6%, shoulder 10.8%, wrist 6.6% and small joints of hand 6.6%). Four workers reported history of white fingers, but the cold water test did not prove it. Deteriorated plethysmographic curve was in 11 cases only. Pathological motor conduction in nervus medianus was found (by EMG investigation) in 13 persons. Carpal tunnel syndrome was acknowledged in 4 individuals as an occupational disease. The results of these investigations show the hazard of dental technicians work and the necessity of improvement of their work conditions.

Adult↗