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Biomedical subjects

M Neves-e-Castro

Publications and source records attributed to M Neves-e-Castro.

11 recordsLinked to original sources

The HERS trial.

Explore the source record for details and available documents.

Clinical Trials as Topic↗

[Should all menopausal women have hormone replacement therapy for the prevention of coronary disease?].

A review of the biochemical changes which occur after menopause. Menopause is the onset of a chronic hypoestrogenism. The lack of estrogens which follows either a premature oophorectomy or menopause is a cause of risk factors and diseases at several levels, amongst which, due to its importance, is the cardiovascular system. Estrogens can favorably modify those risk factors and thus contribute to a sharp decrease in cardiovascular morbidity and mortality. For this reason, its use is legitimate for the primary and secondary prevention of coronary disease.

Cardiovascular Diseases↗

[Androgens and sterility].

The hyperandrogenisms, and in particular those which accompany polycystic ovaries, should always be treated, because the risk of carcinoma of the endometrium and of the breast is increased in these cases. Sterility is inconstant, but can benefit from treatment.

Adrenal Gland Neoplasms↗

Unilateral streaked ovary syndrome. Slotnick-Goldfarbs syndrome.

A case of unilateral streaked ovary (Slotnick-Goldfarb's syndrome) is reported and documented with hormonal, chromosomal, laparoscopic, and histologic studied. It is postulated that viral oophoritis associated with mumps might explain the coexistence of a streaked ovary of a congenital origin with a hypoplastic ovary, tbat would be the expression of a factor acting in postnatal life.

Adult↗