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Biomedical subjects

M Nichelmann

Publications and source records attributed to M Nichelmann.

At least 19 recordsLinked to original sources

[Hyperthermia in the rabbit. I. Studies on influencing circulation with exogenic hyperthermia].

Increasing the environmental temperature to 35 degrees C produced hyperthermia in 11 female rabbits, 80-90 days old. At the onset of hyperthermia the heart rate increased, but there was no further change after about two hours (range 1-3 hours); it remained constant at an increased rate until the end of the experiment. Blood pressure fell at first, but it had increased again after 90 minutes, and underwent no further change during the experiment. The mechanism of these circulatory changes were discussed in relation to the neutral control of body temperature regulation.

Animals

[Hyperthermia in the rabbit. II. Studies on influencing respiration with exogenic hyperthermia].

Rectal temperature, respiratory rate, arterial and venous pH and arterial and venous pCO2 were recorded at intervals of 15-30 minutes in female broiler rabbits exposed an environmental temperature of 35 degrees C, until they died. Respiratory rate and blood pH rose, and pCO2 fell, until a rectal temperature of 42 degrees C was reached. Upon further increase in rectal temperature the respiratory rate and pH began to fall, while pCO2 began to rise. The rabbits died when rectal temperature reached 43 degrees C. Features of respiratory function peculiar to the rabbit were discussed.

Animals