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Biomedical subjects

M Nicolescu

Publications and source records attributed to M Nicolescu.

At least 19 recordsLinked to original sources
PubMed1998

Long-term follow-up after intertrochanteric osteotomies for avascular necrosis of the femoral head.

Between 1978 to 1994, 110 osteotomies were performed in 94 patients. Fifty hips (40 patients) were included in this study. Six hips were in stage II avascular necrosis (Arlet-Ficat staging) and 44 hips were in stage III. In 14 patients an etiologic association was discovered, the remaining 26 were considered idiopathic. The postoperative assessment (Harris score) showed that there is no statistic differences between sexes. Results strongly depend on the amplitude of the necrotic (Kerboul) angle (p < 0.01), the preoperative mobility of the hip (p < 0.01), and age. The best postoperative results are usually obtained in young, active, patients with unilateral involvement, a necrotic angle of less than 200 degrees, a good preoperative range of hip motion, and in which the osteotomy is performed before the collapse of sequestrum.

Adult↗
PubMed1984

May human leptospirosis develop as a chronic infection?

In connection with some rather uncommon cases, the authors asked themselves whether leptospirosis may also develop as a chronic infection. To answer this question, we took into consideration four of the most representative investigated cases encountered during the last 22 years. In conclusion, it appears that in some circumstances, human leptospirosis could present itself as a chronic disease.

Adult↗
PubMedDate not supplied

[Use of culture media with sheep serum for maintenance and isolation of Leptospira strains].

A study was carried out on the effects of a culture medium prepared with sheep serum inactivated at 68 degrees C on Leptospira cultures. Good results were obtained showing that the medium with sheep serum can be used for the cultivation of Leptospira in view of the preparation of antigens for microscopic agglutination and complement fixation. In experiments on the isolation of germs from organocultures and haemocultures the proportion of positive results obtained with sheep serum was smaller than with the media containing rabbit serum.

Animals↗
PubMedDate not supplied

[Physiopathological bases of the treatment of fractures of the trochanteric process].

The proximal end of the human femur represents the result of a long, phylo- and ontogenetic evolutionary process. Its functional structure is determined by biomechamical stresses imposed by the necessities of locomotion and of the upright position, the principal role being that of gravitational pull and the resultant contraction of the two major muscular groups. The older classifications of the fractures of the trochanteral massif, based on anatomical description, is being replaced by the classification based on pathophysiological data, with therapeutic and prognostic value. The notion of instability sets the course in the field of therapeutical principles, of which the most important is, certainly, the refection of the major sustentation pillar--the internal or the calear-femural cortical.

Femoral Fractures↗