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Biomedical subjects

M Nikolić

Publications and source records attributed to M Nikolić.

At least 19 recordsLinked to original sources
PubMed1991

[Specific hormone reactions to aircraft noise in pregnant women].

In order to find out if there is some specific hormonal reaction to JET aircraft noise, a group of eight pregnant women, living in a small suburban community near the airport "Beograd", were investigated. Pregnant women in the first three-months of pregnancy were exposed to the aircraft noise of 75-85 dB/A during 60 minutes, before and after that blood and urine samplers were taken for analyses. Those preliminary result of the level of cortisone, cortisol, testosterone and prolactin suggested that aircraft noise modified the hormonal reaction. Further investigation is needed in order to point out some other possibilities.

Aircraft↗
PubMed1990

Dexamethasone suppression test in patients with Parkinson's disease.

The Dexamethasone Suppression Test (DST), supposed to effectively distinguish between endogenous and nonendogenous depression, was performed in a group of 34 patients with Parkinson's disease. Abnormal DST results were observed in 50% of the patients. The patients were clinically divided into subgroups of depressed and nondepressed parkinsonians. Abnormal DST results were significantly more frequent in depressed (75%) than in nondepressed parkinsonians (27.7%).

Depression↗
PubMed1990

Failure of industrial noise to change the patterns of vanilmandelic acid and 17-hydroxycorticosteroids in the urine of the female weavers with hearing loss.

The field experiments were undertaken on two consecutive working days on seven female weavers with noise-induced hearing loss (NIHL), and a control group of seven sewers with normal hearing. The first day, urine was collected during the shift (06:00-14:00 h) and at home (17:00-05:00 h) for measurements of 17-hydroxycorticosteroids (17-OH) levels. The following day, the procedure was repeated, but for vanilmandelic acid (VMA) analysis. No significant changes in the hormone levels were found, both concerning the different occupational noise exposure and the periods of a working day.

17-Hydroxycorticosteroids↗
PubMed1987

Depression and Parkinson's disease: possible role of serotonergic mechanisms.

Depression is frequently encountered in Parkinson's disease and was seen to occur in 14 of 26 patients studied. The levels of 5-hydroxyindoleacetic acid (5-HIAA), the main metabolite of serotonin (5-HT), in CSF samples of the patients were significantly lower than in those of controls. However, within the group of patients the levels of 5-HIAA in CSF samples were significantly lower in the depressive subgroup compared with the non-depressive patients. Moreover, no correlation was recorded between motor disability and depression. The results indicate that disturbed 5-HT metabolism may possibly play a role in Parkinson's disease as a predisposing factor in the development of depression.

Aged↗
PubMed1987

Cyclic nucleotides in cerebrospinal fluid of drug-free Parkinson patients.

Concentrations of cyclic nucleotides--adenosine-3',5'-monophosphate (c-AMP) and guanosine-3',5'-monophosphate (c-GMP)--were measured in cerebrospinal fluid (CSF) of 17 drug-free Parkinson patients and 12 controls. No significant difference between the cyclic nucleotide contents (p greater than 0.05) in CSF of patients and controls was detected, nor was there a correlation between the content and the degree of neurological disability. Besides, no changes in the cyclic nucleotide contents were detected in the subgroups of patients according to the prominence of tremor or rigidity/akinesia as the main symptoms of the disease.

Cyclic AMP↗