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Biomedical subjects

M Njeh

Publications and source records attributed to M Njeh.

At least 19 recordsLinked to original sources

[Hodgkin's disease with esophageal involvement].

INTRODUCTION: Esophageal involvement in Hodgkin's disease, commonly known as a belated localization of the advanced forms, has been seldom reported (3 to 5% in post-mortem series and 0.7% in clinical series). EXEGESIS: We report the case of a 61-year-old man who had an esophagus localization revealing Hodgkin's disease stage IV EBb of Ann Arbor classification. The originality of this case was represented by: the revelation mode of the esophageal involvement such as dysphagia and upper gastrointestinal bleeding; the localization at the distal third of the esophagus with contiguous involvement of the gastric fundus; the absence of mediastinal nodes showing the primitive character of the esophageal injury. CONCLUSION: This observation incites us to consider Hodgkin's disease in the list of differential diagnoses of tumoral dysphagia, even if there was no ganglionic and/or visceral localization of the disease.

Anemia, Hypochromic↗

[The pathological prostatic utricle: two case reports].

The prostatic utricle is a small vestigial diverticulum on the posterior surface of the prostatic urethra. It is considered to be pathological when it is abnormally dilated. The prostatic utricle is revealed by signs of vesical irritation and dysuria, sometimes associated with a retrovesical mass on examination. The authors report two cases of pathological prostatic utricle. The first case was an 11-year-old boy presenting with dysuria. Retrograde cystourethrography confirmed the diagnosis. The utricle was resected via a transtrigonal intravesical approach. The second case was a 25-year-old man who presented with dysuria associated with a pelvic mass. IVU and ultrasonography suggested a diagnosis of retrovesical cyst. This patient underwent incomplete resection of the utricle via a retrovesical approach. Based on a review of the literature, the authors emphasize the need to look for a prostatic utricle in a young subject presenting with dysuria, particularly in patients with a malformation of the genitourinary tract (hypospadias, renal agenesis). All pathological prostatic utricles must be treated surgically. The incision is transtrigonal in medium-sized utricles and transperitoneal in large utricles. The utricular cavity must be resected as completely as possible.

Adult↗

[Traumatic rupture of the anterior urethra. Apropos of 18 cases].

The authors report a retrospective series of 18 cases of rupture of the anterior urethra, with a mean age of 25 years (range: 10 to 45 years). The mechanism of the lesion was trauma by falling onto the perineum (12 cases), road accident (4 cases) and sexual intercourse (2 cases). Urine drainage was ensured by suprapubic catheter (15 cases) or urethral catheter (1 case). The two cases of rupture of the urethra associated with lesions of the corpora cavernosa required urgent surgical repair. In the other cases, simple urine drainage was sufficient to treat partial ruptures of the urethra (11 cases) with only one case of urethral structure. However, end-to-end urethrorraphy was performed in the 4 patients with total rupture of the urethra, with early failure in 3 cases, attributed to delayed surgery. Finally, the course of urethral rupture associated with rupture of the corpora, cavernosa was favourable in terms of both micturition and sexual function.

Accidents, Traffic↗

[Serious urinary infections and pregnancy].

Retention of infected urine in the upper urinary tract which is due to obstruction is a serious condition during pregnancy. The authors report their experience on five cases and propose attitudes to adopt against such emergency. Ultrasounds allow accurate diagnosis of the obstruction and may be helpful to find its etiology. Plain X ray film could be of interest mainly for stone recognition after the third month of gestation. Surgical treatment, when possible allows either relief of obstruction and cure of the original disease, otherwise performance of percutaneous nephrostomy represents a better way of drainage until the end of pregnancy.

Adult↗

[Adrenal pheochromocytoma. Report of six cases].

The authors report 6 cases of adrenal pheochromocytoma seen over a period of 3 years (1993-1995). All patients were females, aged between 17 and 43 years with a mean of 35 years. Clinical manifestations consisted of either sustained hypertension, with episodes of hypersudation and palpitations, or paroxysmal hypertension which was revealed during surgery ; the disease was sometimes discovered incidentally. C.T and ultrasound showed in every cases adrenal mass as 3 to 6 cm usually located on the left side (5 cases). All patients were operated via lumbotomy and adrenalectomy was performed. In one case an associated thrombus within the vena cava was removed. Postoperative follow-up was uneventful except for one patient who developed a recurrent episode of hypertension.

Adolescent↗

[Bladder hernia apropos of a case report].

The authors report a case of bladder hernia associated to prostatic benign hyperplasia. The diagnosis is confirmed by intra-venous urogram and computed tomography imaging. The reintegration of the bladder in the abdomen was performed in association to endoscopic resection of the prostate. Bladder hernia is rare condition. Surgical treatment of bladder hernia is associated to the etiology (prostatic benign hyperplasia...) of the hernia to prevent recurrence.

Diagnostic Imaging↗

[Bladder hernias].

The authors report 5 cases of bladder herniation through inguinal ring. All the patients were males aged between 52 and 72 years with a mean of 63 years. The clinic symptoms were non specific. In four cases the diagnosis was made by IVP. In the fifth case the bladder herniation was discovered after an incidental opening of the bladder during a right inguinal hernia repair. Four patients were operated on for replacement of the bladder and repair of the hernial ring; the procedure followed was Mac Vay technique in two cases, Shouldice in one case and placement of a Mersuture prosthesis in another case. The fifth patient was operated on because of major constraint related to his general conditions. Results was quite satisfactory in all operated cases with a mean control of 24 months.

Aged↗

[Cancer of the testis in cryptorchidism. Apropos of 5 cases].

Five cases of cancer of the testicle in patients with cryptorchidism are presented. In one case the tumour occurred 16 years after cure for cryptorchidism at 15 years of age. In the other cases, the tumour developed on a testicle in an inguinal or intra-abdominal position. In two cases, it was impossible to remove the tumour which had developed on an intra-abdominal position. These patients died. These cases emphasize the importance of surgical cure in all cases of cryptorchidism, preferable before the age of 2 years, in order to improve functional prognosis and reduce the risk of cancerization. The gravity of cancer of the testicle in cases of cryptorchidism is often discovered too late.

Adult↗

[Urinary calculi in a geriatric setting].

The authors report a retrospective series of 174 patients with urolithiasis. They were all age between 65 and 88 years. This group represents one tenth of all patients treated for urinary stones in the Urology department of Sfax over the last decade. Neither the clinical symptoms nor radiological findings observed in this group differed from those other patients hospitalized for urolithiasis; on the other hand associated diseases related to aging appear to be well represented which alters the management, prognosis and outcome in this type of patients.

Aged↗

[A modified cervico-prostatic incision technic in hypertrophic adenoma in young subjects desiring to preserve ejaculation].

The treatment of bladder neck obstruction by transurethral resection of the prostate is responsible for retrograde ejaculation, which is poorly tolerated by our younger patients. Bladder neck incision, initially proposed as treatment for bladder neck sclerosis and for small prostates, was performed according to a modified technique in 36 patients with a mean age of 57.6 years (range: 41-72 years), with benign prostatic hypertrophy less than 30 grams and wishing to retain antegrade ejaculation. This technique consists of creating a deep groove with the resector hook extending from the ureteric orifice to 5 mm above the verumontanum, incising the full thickness of the detrusor and prostatic urethra as far as the retrocervical fat. This preserves a supramontanal ring of urethral muscle whose contraction during orgasm prevents retrograde ejaculation of semen. Resection of the median lobe was also performed in 8 patients, while sparing the cervical muscular ring. The mean follow-up was 2.4 years (range: 4-84 months). Dysuria was very considerably improved in 32 patients (91.5%), with a Madsen score of less than 2. Antegrade ejaculation was preserved in 32 patients (91.5%). Two patients had to undergo secondary prostatic resection because of persistent dysuria (these 2 patients retained antegrade ejaculation). Unilateral bladder neck incision, sparing a supramontanal muscular ring is an easy, rapid technique with low morbidity, effective in the treatment of prostatism due to a small prostate (less than 30 grams). It is the operation of choice in young patients with small prostates who wish to retain antegrade ejaculation.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[Nephrectomy in children. Apropos of 55 cases].

Based on a series of 55 children undergoing nephrectomy, the authors describe the clinical, laboratory, radiological, therapeutic and prognostic features for each aetiology. They define the criteria for resection of the affected kidney.

Adolescent↗

[Bladder tumors in patients under 40 years of age].

A total of 13 patients under the age of 40 years were treated for bladder carcinoma. One child had a bladder sarcoma. 8 patients had a superficial transitional cell carcinoma with no evidence of recurrence after endoscopic resection. Four patients had invasive bladder carcinoma. Superficial bladder carcinoma would appear to have a good prognosis in patients under 40 years of age.

Adolescent↗

[Male internal pseudohermaphroditism or a man with a uterus].

Mullerian structures were discovered during cure of bilateral ectopic testes in a 14-year-old boy. The original feature of this case was the presence of both testes on the same side. The Mullerian structures were left in place as they were intimately adherent to the vas deferens. This attitude was adopted as no degeneration of these structures has been described and because of the possibility of reproduction of these patients during adulthood.

Adolescent↗

[Extra-renal retroperitoneal angiomyolipoma].

Angiomyolipoma is a benign kidney tumour. Its extrarenal, retroperitoneal site is exceptional. The authors report a case and emphasise the value of ultrasonography and computed tomography in the diagnosis of these tumours with a marked fatty component, without neglecting the contribution of arteriography which can be useful in the diagnosis of the origin of very large retroperitoneal tumours.

Angiomyolipoma↗

[Renal tuberculosis with pseudotumoral form: apropos of a case].

The authors report about one rare case of renal tuberculosis in a pseudo-tumoral form, which had radiologic appearances compatible with a kidney cancer invading soft tissue. The fast spontaneous evolution towards fistulization allowed confirming the diagnosis of urinary tuberculosis. The outcome with treatment was favorable. The authors recommend that needle biopsy should be made in cases of doubtful kidney tumors to provide an exact diagnosis.

Aged↗