Biomedical subjects

M O Obajimi

Publications and source records attributed to M O Obajimi.

30 records · Page 2Linked to original sources

PubMed1996

Radiological evaluation of orbital tumours in Ibadan, Nigeria.

Tissue diagnosis of orbital tumours is especially difficult because of the wide range of tissues normally occurring in the orbit [2]. Unfortunately, such tumours are relatively surgically inaccessible for biopsy due to the presence of the bony walls of the orbit and its peculiar shape. This gives rise to a need for effective methods of indirect assessment of the orbit and its contents prior to definitive therapy. Such indirect assessment may be achieved using certain modalities of radiological imaging. These include conventional plain X-ray films, ultrasound scan (USS) and computerized axial tomography (CAT scan), orbital venography and magnetic resonance imaging. This paper is a pilot study of current practices in the use of radiological imaging techniques in the diagnosis of orbital tumours at a University Hospital.

Adolescent↗

PubMedDate not supplied

Computed tomographic evaluation of Pott's disease in Accra.

BACKGROUND: Radiological investigations are central in the diagnosis and management of TB spine. In Ghana there is a dearth of literature on the disorder. This paper seeks to describe the CT features of the bony and soft tissue changes in Pott's disease. METHOD: It is a descriptive report of the CT scans performed on 30 patients with proven Pott's disease from January 1998 to December 2000 at the Korle Bu Teaching Hospital Accra, Ghana. RESULTS: The disorder was common among children and young adults (76.7%). Chronic back pain was the frequent presenting complain (53.3%). The dorsal spine remains the site of preference while T11 recorded the highest incidence (73.3%). The vertebral body was destroyed in all the cases and the fragmentary type of bone destruction was the common observation. The incidence of cord compression demonstrated by CT was high (73.3%). Other findings were paraspinal and epidural masses observed in (66.7%) and (73.3%) respectively. CONCLUSION: CT images demonstrated the spinal level of destruction. Improved resolution also showed detailed changes within the outlined soft tissue masses, facilitating early diagnosis and prompt initiation of therapy.

Adolescent↗

PubMedDate not supplied

Computed tomography (CT) in civilian gunshot head injuries in Ibadan.

BACKGROUND: There is data on civilian gunshot injuries in Nigerians. The purpose of the study is to describe the Computed Tomography findings of civilian gunshot injuries (GSI) to the head in Ibadan, Nigeria. METHOD: This is a retrospective study of Computed Tomography (CT) films and clinical records of 28 consecutive civilian gunshot injuries to the head from 1996 to 1999. RESULTS: The gunshot injuries to the head were mostly armed robbery related. Though there was a steady annual increase of civilian gunshot injuries during the study period, a low CT Scan frequency (0.61%) was recorded. The following CT findings were present in all the patients; bullet fragments, intraparenchymal haemorrhage, vault fractures and soft tissue swelling. The resting position of the bullets showed a predilection for the parietal lobe (32.1%) and the most common fracture site was also the parietal bone (42.8%). CONCLUSION: CT findings simplified the management of civilian gunshot injuries to the head in the patients studied by demonstrating the exact pathology sequel to the injury. Despite important constraints, CT remains a cost effective means of managing GSI to the head.

Adolescent↗

PubMedDate not supplied

Computed tomography and childhood seizure disorder in Ibadan.

BACKGROUND: Computed Tomography (CT) is an important tool for neuroimaging, it offers an opportunity to investigate structural lesions as a cause of seizures with little morbidity. This study is designed to evaluate it's applicability in children with epileptic seizures. METHOD: It is a descriptive study of the CT scans of the 103 consecutive children who were referred to the CT suite of the University College Hospital on account of seizure disorders over a 5 year period (1997--2001). RESULTS: Only 103 (4.6%) of the subjects who had cranial scans done in five years were children with seizures disorders. The CT scans were abnormal in 53 (51.5 %). Hydrocephalus was the most common finding in 14 (13.6%). Cerebral atrophy and infarct were reported in 10.6% and 8.7% respectively. The outlined cranial fractures found in 6.8% were all depressed. A high incidence (74.4%) of abnormal scans was reported in the children with partial seizures. Thirty-three (62.3%) of the abnormal scans were amenable to surgery. The presence of neurologic deficit increased the yield of abnormal CT features. CONCLUSION: CT scans are of extreme value in the screening and definitive evaluation of seizures in children. It is advocated for excluding treatable conditions and monitoring progression of the disorder.

Adolescent↗

PubMedDate not supplied

Computed tomographic evaluation of TB spine in Ibadan.

BACKGROUND: Tuberculosis still remains a major problem in the developing countries. The involvement of the spine is also of increasing importance, because of the resurgence of TB in association with AIDS. This paper is designed to evaluate the applicability of CT in the diagnosis and definition of tuberculosis of the spine in Ibadan. METHOD: A restrospective study of the Computed Tomographic examination of 22 cases of spinal tuberculosis (Pott's disease) over a four-year period at the Radiology Department of the University College Hospital, Ibadan. RESULTS: There was a male prevalence in the study. The mean age of respondents was 41.2 years. Neurological symptoms and back pain were the most common presentations. The thoracic spine was mostly involved while the cervical spine was least involved. Most lesions 77.3 % were demonstrated in two contiguous vertebral bodies. The vertebral bodies were destroyed in all the patients while the posterior elements were involved in 59%. The other CT findings were paravertebral soft tissue shadow in 40.9%, narrowed irregular disc spaces in 27.3% and fusion of vertebral bodies in 13.6%. The frequent bony destruction was osteolytic in nature, and was present in 64% of patients. CONCLUSION: CT is an adequate modality for thorough imaging and diagnosis of Pott's disease especially in patients with non specific or ambiguous presentations. It offers a unique opportunity of demonstrating clearly the various component of the spine, it also defines the pattern and extent of the destructive process.

Adolescent↗

PubMedDate not supplied

Computerised tomographic detection of intracranial complications of paranasal sinus infections.

Ninety-four patients were referred for CT examination of the paranasal sinuses within a five year period. Only 11 (11.7%) of them had intracranial complications. These include cerebral, subdural and epidural abscesses, frontal bone osteomyelitis. The maxillary and ethmoidal sinuses were mostly involved and can be implicated as the sinogenic causes of intracranial infections. Sphenoidal sinus was not involved in any of the patients.

Adolescent↗

PubMedDate not supplied

Cranial computed tomographic (CT) findings in HIV-positive Nigerian patients presenting for neurosurgical evaluation.

INTRODUCTION: The central nervous system (CNS) is an important site of HIV infection. As many as one quarter of AIDS patients present with neurological symptoms and up to 75% of the patients may have CNS abnormalities at autopsy. Under these circumstances therefore, differential diagnoses in HIV-positive patients with neurological symptoms constitute a management challenge. OBJECTIVE: To describe the pattern of cranial computed tomographic (CT) findings in neurosurgical patients with HIV infection. STUDY DESIGN: Retrospective analysis. PATIENTS AND METHOD: A total of 1907 patients were admitted from October 1996 to October 2001. Sixteen patients were positive for HIV using the Western blot. We reviewed their biodata, clinical features and cranial CT findings. RESULTS: There were 10 male and 6 female patients. Twelve patients had cranial CT. Four patients had lesions that could be attributed to direct infection by HIV virus. Two patients had lesions that suggested immunosuppression from HIV infection. Diffuse breakdown in blood brain barrier (BBB) with contrast enhancement as well as mass effect that was disproportional to the enhancing lesion were common findings in three patients. The other lesions seen on cranial CT could not be directly linked to HIV infection. CONCLUSION: Apart from the diffuse breakdown in blood brain barrier with disproportional mass effect, our findings were similar to previous reports. Further study with a larger population of patients and, especially, biopsy of the CNS lesion will be needed to confirm our findings.

Adult↗

PubMedDate not supplied

Radiological evaluation of head trauma by computer tomography in Ibadan, Nigeria.

The computed tomography (CT) findings of 419 patients with head injury were reviewed. 254 (60.62%) showed abnormal CT findings while 165 (39.38%) had a normal CT examination. Pathological states, which were easily demonstrated by CT, include traumatic haemorrhages (i.e. intracerebral bleed 67 cases (26.3%), Subdural haematoma 73 cases (28.7%), cerebral oedema and other cerebral sequelae of trauma such as porencephalic cysts, cerebral infarction and leukodystrophy. Patients with focal neurological deficit showed more positive findings than those without. A total of 73 (17.42%) patients had fractures demonstrated on CT. 39 (23.2%) of the 168 patients with traumatic haemorrhages had associated fractures. Fractures were detected more in patients with intracerebral and epidural haemorrhages than subdural haemorrhages. Plain skull radiography alone is therefore not sufficiently valuable in investigating patients with head injury. Computed tomography, no doubt, offers an excellent method of investigating the patient with head injury in that it demonstrates intracranial or cerebral lesions that may or may not be associated with fractures; and which might be missed if CT is not done. CT examination should be obtained where it is available if clinical indication warrants it and when CT is to be done, plain films are irrelevant since CT with bone window settings and with 3D reformation would show fractures.

Adolescent↗

PubMedDate not supplied

Radiological ageing process in the cervical spine of Nigerian women.

The study was designed to determine the age of commencement of ageing process in Nigerian women Four hundred (400) consecutive women requesting for cervical spine radiographs where recruited for this study. A study chart was made showing different variables like osteoarthrosis, detached osteophytes, postural ulterations and disk degenerations in a four year period from 1st January, 1993 to 31st December, 1996 the modified Kellgren and Lawrence grading system was used to assess radiographic changes. The highest rate of osteoarthrosis (31.13%) was found in the fifth decade. Incidence of postural alterations of the cervical spine rose sharply in the 5th and 6th decades of life. Grade 2 osteoarthrosis (Kellgren and Lawrence) was commonest (61.3%); Grades 3 and 4 had the lowest incidence (3.45%). Disc degeneration was commonest in the 5th; the most involved disc was C5/C6 and the least involved was C2/C3. It is concluded that the ageing process in the Nigerian women commences in the fourth decade of life, and apparently shows no difference with caucasian women.

Adult↗

PubMedDate not supplied

Spontaneous intracranial haemorrhage: computed tomographic patterns in Accra.

The diagnosis of stroke and the ability to distinguish the subtypes is central in the management of patients. This CT study has confirmed an increased prevalence of stroke (CVA) among Ghanaians. It has also reaffirmed a relatively higher incidence (52.9%) of spontaneous intracranial haemorrhage over cerebral infarcts among the 1,172 stroke patients studied. The study points to a male preponderance and a mean age of 55.7 years. Parenchymal haemorrhage was found to be the commonest variety of these haemorrhages. It occurred in 83.6% of cases while primary subarachnoid haemorrhage was reported in only 8.1% of cases. Ventricular extension of the parenchymal haemorrhage was reported in 22.7% of cases. The latter were mostly unilateral and on the left side especially in the parietal lobe (70.9%), subdural haemorrhage like the parenchymal variety was also reported to be more on the left, mainly unilateral and acute. Haemorrhages in the cerebellum and pons which are normally difficult to diagnose were also outlined with ease in the CT images. Other CT findings in these patients include parilesional oedema and mass effect found in 87.10% and 77.4% respectively.

Adolescent↗

PubMedDate not supplied

Computed tomographic patterns of intracranial infarcts in Ghanaians.

Computed tomography has given a boost to intracranial imaging in general, and the diagnosis of the subtypes of Cerebrovascular Accident (CVA) in particular. In this study of 1,172 cases of CVA examined by Computed Tomography (CT), 552 (47.10%) showed features of cerebral infarction. There was a male prevalence in the study and the mean age was 59.8 years. As in all infarcts the diagnostic appearance was a wedge shaped hypodensity within the brain parenchyma. This was most often found in the parietal lobe (73.6%) and was always without a mass effect. Even though solitary infarcts were frequent, multiple lesions were reported in 9.3% of cases and these group of respondents presented mostly with seizures. Diabetes mellitus was an important predisposing factor and was found in 163% of cases, while hypertension was found in only 9.1% of cases studied. Other CT findings were cerebral and cerebrellar atrophy. Calcification of the falx and the basal ganglia were also noted.

Adolescent↗

PubMedDate not supplied

Cholelithiasis in Ibadan: an update.

This study is to ascertain the present status of cholelithiasis in our environment. Six hundred and seventy (670) consecutive abdominal, ultrasounds done for various abdominal complaints at the University College HospitaL Ibadan from January 1977 to December 1998 were studied for gall stones in addition to other studies of the abdomen. Only twelve (12) gallstones were found, giving a prevalence of 1.79%. Only 25% were silent stones. The male:female ratio was 1:3. The mean age was 30 years (S.D = 2.8) and peak age was between 30 and 40 years. The average body mass index (B.M.I) was 23.49 kg/m2 (S.D = 3.9). The average parity among the women was four (4). Only one ultrasound was false (false negative). This study shows an increase. In prevalence over previous figures (1.79%) as against 0.007% in the sixties). The peak age is a decade lower and the anthropometric measurements in our patients do not support the typical caucassian model.

Adult↗