PubMed Health⌕ Search

Biomedical subjects

M O Senac

Publications and source records attributed to M O Senac.

30 records · Page 2Linked to original sources

Early costochondral calcification in adolescent hyperthyroidism.

The finding of extensive costochondral calcification in five adolescents, aged 14-16 years, with hyperthyroidism prompted a retrospective study of all young persons with this condition seen in the last 10 years. Thirty-six patients with hyperthyroidism (ages 13-18 years) were evaluated. Of 32 thyrotoxic teenage girls, 21 (66%) showed some degree of calcification, compared with 73 of 600 (12%) in the control group. Only four boys were evaluated, but one had grade 2 (mild) calcification that was not seen in any boy in the control group. Costochondral calcification increases with age and continues throughout life, reflecting the aging process. The much higher incidence of early costochondral calcification in thyrotoxic adolescents than in the general population is a radiographic indication of advanced bone maturation not previously recognized.

Adolescent↗

Intraspinal seeding from intracranial tumors in children.

Cerebrospinal fluid-borne metastases were demonstrated by metrizamide myelography in 20 children with primary intracranial tumors, posterior fossa medulloblastomas being the most common. The lumbosacral region was affected most often, with nerve root thickening, nodularity, and irregularity of the thecal sac. Cord cloaking, nodularity, and meningeal disease were common in the cervical and thoracic areas. Intraspinal spread from primary intracranial tumors signals a poor prognosis. However, the early detection of intraspinal spread afforded by metrizamide myelography can alter therapy and thereby improve prognosis.

Brain Neoplasms↗

Syringohydromyelia following meningomyelocele surgery--role of metrizamide myelography and computed tomography.

Five children developed symptoms attributable to syringohydromyelia several years following neonatal surgery for lumbosacral meningomyelocele. Metrizamide injection followed by computed tomography (CT) was performed in all five patients. In two patients, there was direct opacification of both the subarachnoid space and the syringohydromyelia. In a further two patients, delayed CT demonstrated late opacification of the central cavity from contrast introduced into the subarachnoid space. In the fifth patient via a suboccipital puncture, there was fortuitous filling of a caudally displaced fourth ventricle communicating with a central cavity within the cord, but there was no visualization of the subarachnoid space. Surgery with decompression and plugging of the obex halted the progression of the disease in all the patients.

Adolescent↗

Evaluation of obstructive uropathy in children: radionuclide renography vs. the Whitaker test.

Differentiation of obstructed from dilated, nonobstructed urinary systems in the postoperative child is a difficult diagnostic problem. A comparison study was performed in 21 children with hydroureteronephrosis using the Whitaker test in combination with conventional radionuclide renography and/or diuretic (furosemide)-augmented radionuclide renography. The results of each method were correlated with the clinical assessment and surgical findings. Conventional renography was found to be an unreliable study, with a clinical correctness of only 57%. Results were more favorable for both the Whitaker test and diuretic-augmented radionuclide renography, with clinical correctness in 86% and 85%, respectively. Furthermore, when both tests agreed, no false negatives or false positives were obtained. Due to the noninvasive nature of the study, diuretic-augmented renography should be the initial procedure once hydroureteronephrosis is established. A recommended algorithm of the child with postoperative hydroureteronephrosis is suggested.

Adolescent↗

Embolotherapy of a ruptured internal mammary artery secondary to blunt chest trauma.

A unique case of traumatic rupture of the internal mammary artery secondary to blunt deceleration injury of the chest is reported. The injury, which produced changes consistent with great vessel disruption on the plain chest radiograph, was treated by percutaneous transcatheter embolization of Gianturco steel coils. The importance of surveying all arteries visualized during thoracic aortography in patients with widened mediastinum following deceleration injury to the chest is reinforced. Embolotherapy of this noncritical chest wall vessel is demonstrated.

Accidents↗

Incidence of short trachea in patients with myelomeningocele.

Short trachea, typically due to reduced tracheal cartilage ring number, produces high tracheal bifurcation which can be demonstrated in radiographs with evaluable air bronchograms. Accidental bronchial intubation with sequelae has been reported in short trachea patients who have tracheal intubation. Short trachea is associated with a number of syndromes, including DiGeorge anomaly and several types of congenital heart disease and skeletal dysplasias. Review of chest radiographs of 87 patients with myelomeningocele revealed that 31 (36%) had short tracheas. Two patients had a total of 3 episodes of bronchial intubation. This degree of association of short trachea with myelomeningocele, the frequency of myelomeningocele, and the number of surgical procedures performed on many such patients suggest that special attention to the short trachea is warranted in myelomeningocele patients because of the risk of accidental bronchial intubation and subsequent sequelae. Twelve (14%) of the myelomeningocele patients lacked radiographic evidence of the presence of twelfth ribs and 11 (13%) had hypoplasia of the twelfth ribs.

Adolescent↗

Prevalence of incidental paranasal sinuses opacification in pediatric patients: a CT study.

A prospective evaluation of the paranasal sinuses was performed on a consecutive series of 137 pediatric patients referred for cranial CT. Approximately one-half of the patients less than 13 years of age had some degree of maxillary or ethmoid sinus opacification. The prevalence and severity of opacification was approximately the same for the maxillary and ethmoid sinuses. Sphenoid sinus abnormality was less common (16% of patients) and was usually minimal or mild. No incidental frontal sinus abnormalities were observed. This study confirms previous reports, based on plain film radiography, of the prevalence of incidental maxillary sinus opacification in children. However, contrary to some prior studies, we did not find a relatively higher rate of opacification in children less than 1 year of age. This may be due to overdiagnosis of maxillary sinus opacification on plain films, in small children. The diagnosis of sinusitis in childhood must take into account not only the radiographic findings but clinical signs and symptoms. Correlation is needed to avoid overdiagnosis in patients referred for sinus radiography for nonspecific indications or who have incidental opacification noted on radiographic or CT studies of the skull and brain.

Adolescent↗