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Biomedical subjects

M Ochocka

Publications and source records attributed to M Ochocka.

At least 55 records · Page 3Linked to original sources
PubMed1983

Morphometric ultrastructural analysis of nuclear components in T-cell acute lymphoblastic leukaemias.

The paper deals with the morphometric ultrastructural analysis of the nuclear components performed in five cases of T-cell acute lymphoblastic leukaemia. All these cases constituted a homogeneous group in clinical and immunological evaluation. The cases analysed did not differ in cell nucleus and euchromatin volume as well as in their number of nucleoli per one cell profile.

Cell Nucleolus↗
PubMed1982

Morphometrical ultrastructural evaluation of the cytoplasmic components in acute lymphoblastic leukaemias of T-cell type.

Immunological and ultrastructural morphometric evaluation of the cytoplasmic components of cells was performed in five cases of acute lymphoblastic leukaemia of the T-cell type. All cases were a uniform group as regards clinical and immunological evaluation. On the basis of the mean cell diameter, the volume fractions and true volumes of cell organelles, cells from various cases of acute lymphoblastic leukaemia were found to be no homogeneous group. The cases examined were most homogeneous as far as the volume fraction of the Golgi apparatus and the true volumes of the cell nucleus, mitochondria, lysosomes, smooth and rough endoplasmic reticulum and Golgi apparatus were concerned.

Biometry↗
PubMed1980

Influence of vincristine on the Golgi complex of leukaemic lymphoblasts.

In vitro and in vivo effects of vincristine on the Golgi complex of leukaemic lymphoblasts were studied. The cells incubated in vitro for 4 hours with vincristine of 1.25 x 10(-5) M concentration lacked microtubules, but regularly contained paracrystals and parallel arrays of macrotubules associated with ribosomes. The Golgi complex in control lymphoblasts was represented by 1-3 dictyosomes (stacks of cisternae) grouped in one area. After exposure to vincristine the dictyosomes lay at a considerable distance from each other. In many of them the cisternae were shorter than in controls and distended or transformed into large vacuoles. In cells incubated in vitro with lower concentrations of vincristine (1.25 x 10(-6) and 1.25 x 10(-7) M) and in cells obtained after the second therapeutic dose of vincristine (in the course of normal clinical treatment) neither changes in the Golgi complex nor formation of paracrystals and macrotubules were observed.

Adolescent↗