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Biomedical subjects

M Oner

Publications and source records attributed to M Oner.

11 recordsLinked to original sources

[Production of rifamycin complex].

In this study, by using synthetic medium and Streptomyces mediterranai rifamycin was produced by fermentation in laboratory scale. By means of spectrophotometric determination and microbiological assay, production of antibiotic by the organism was proved.

Culture Media↗

[Production of vitamin B12 by fermentation].

In this work, the methods and technology of vitamin B12 production were studied on laboratory scale. The microorganisms used for experiments were Streptomyces olivaceus IFO 3409, Streptomyces olivaceus CBS 355.53 and Streptomyces griseus CBS 161.45 which were brought from foreign countries. Vitamin B12 activity that have been obtained from fermentation experiments of each microorganisms are determined by microbiological assays using Lactobacillus leichmannii IFO 3073 (ATCC 4797) which is a test microorganism. As a result of these assays S. olivaceus IFO 3409 (2 micrograms/ml) was found as the most efficient strain were followed by S. olivaceus CBS 355.53 and S. griseus CBS 16.45 respectively.

Biological Assay↗

Electroencephalographic study in acute rheumatic carditis.

Electroencephalographic studies were done in rheumatic fever patients in order to determine the distribution of normal and abnormal EEG patterns in different clinical forms. The duration of EEG abnormalities related to rheumatic activity was compared with the duration of increased sedimentation rate and tachycardia. Rheumatic fever cases were divided into four groups: (1) acute active rheumatic carditis, (2) acute polyarthritis without carditis, (3) nonactive old rheumatic valvular heart disease, and (4) Sydenham's chorea. EEG findings were within normal limits in acute polyarthritis and in nonactive rheumatic valvular heart disease, but there were abnormal EEG findings in 29 per cent of chorea and in 94 per cent of active carditis cases. In active carditis all EEG changes returned to normal approximately within 8 weeks, whereas the sedimentation rate and tachycardia returned to normal within a shorter period.

Adolescent↗