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Biomedical subjects

M Osnes

Publications and source records attributed to M Osnes.

53 records · Page 3Linked to original sources
PubMed1977

Juxtaminorpapillary diverticulum associated with chronic pancreatitis.

A 69-years-old male with a juxtaminorpapillary diverticulum of Santorini in the duodenum and chronic pancreatitis is described. The patient had suffered from attacks of epigastric pain during the last 35 years. At recent admission to hospital he had also an elevated urinary amylase activity and a juxtaminorpapillary diverticulum, demonstrated by duodenoscopy and X-ray examination after administration of a contrast medium. Endoscopic retrograde cholangio-pancreatography (ERCP) showed changes of the pancreatic duct system compatible with chronic pancreatitis, a diagnosis which was confirmed by explorative laparotomy.

Aged↗
PubMed1977

Early gastric carcinoma in patients with a Billroth II partial gastrectomy.

In a consecutive series of 830 routine gastroscopies a total of 43 patients was found with gastric carcinomas, Thirteen of these were patients with a previous Billroth-II operation for ulcer disease. Early cancers were found in ten patients (23%), and four of these ten (3 men, 1 woman, aged 49 to 76 years), had been operated on 20-33 years previosuly with a Billroth II partial gastrectomy. All patients had symptoms indicating gastro-intestinal disease. We conclude that a high number of gastric stump carcinomas may be detected at an early stage, and that endoscopy of the whole gastric stump, with multiple biopsies and brush cytology from the entire gastro-jejunal anastomosis, is of crucial importance in detecting such carcinomas.

Adenocarcinoma↗
PubMed1977

Endoscopic choledochoduodenostomy for choledocholithiasis through choledochoduodenal fistula.

A new endoscopic method for treatment of choledocholithiasis in patients with choledochoduodenal fistula is described. In 2 patients with common bile duct stones a choledochoduodenostomy was performed by means of a diathermy snare. In both patients the calculi passed into the duodenum within some days. No complications occurred. It is concluded that the described technique may be helpful when surgery is contraindicated and when endoscopic papillotomy is difficult to perform.

Aged↗
PubMed1977

Juxtapapillary duodenal diverticula and abnormalities by endoscopic retrograde cholangio-pancreatography (ERCP).

In a consecutive series of 174 patients the biliary and pancreatic ducts were demonstrated by endoscopic retrograde cholangio-pancreatography (ERCP). In 84 patients with normal duct systems, juxtapapillary diverticula were found in 5 patients (6%). In 90 cases with ductal abnormalities due to biliary concrements, dilated common bile duct and pancreatitis, diverticula were found in 35 patients (39%). In patients with abnormalities in both duct systems, diverticula were found in 52%, and in patients with changes in one duct system diverticula were found in 33%. The difference in occurrence of diverticula in patients with normal duct systems and pathological duct systems was statistically significant (p less than 0.02). The findings indicate a correlation between juxtapapillary diverticula and pathological changes due to biliary concrements, dilated common bile duct without concrements and pancreatitis.

Biliary Tract Diseases↗
PubMed1977

A comparison of a new non-ionic (metrizamide) and a dissociable (metrizoate) contrast medium in endoscopic retrograde pancreatography (ERP).

Endoscopic retrograde pancreatography (ERP) was performed on 12 patients with a non-ionic contrast medium (metrizamide) and a traditional dissociable medium (metrizoate). All patients were examined with both media at an interval of one week. The study was based on double blind and a cross-over randomization. There was a significantly lower rise in serum amylase 2 (p = 0.05), 4 (p = 0.04), and 6 hours (p = 0.03) after the examination using the non-ionic contrast medium than after using a dissociable one. The pain during contrast filling of the pancreas was significantly lower (p = 0.015) when using metrizamide than when using metrizoate. All, except one patient, preferred the examination with the non-ionic contrast medium (p = 0.0002). A positive correlation was found between pain and degree of pancreatic filling when using the dissociable medium (r = 0.77). Such a correlation could not be detected following the non-ionic contrast medium (r = 0.009). There was a positive correlation between rise in serum amylase and degree of pancreatic filling with both contrast media. The coefficient of correlation was lower after metrizamide (r = 0.21) than after metrizoate (r = 0.56). It is concluded that a non-ionic contrast medium in this study was better tolerated than a dissociable medium, and that metrizamide was more suitable for endoscopic retrograde pancreatography than the traditional hypertonic contrast medium.

Adult↗
PubMed1977

Endoscopic papillotomy (EPT) with removal of common bile duct stones.

Endoscopic papillotomy with removal of common bile duct stones was successfully performed in 14 patients. In 11 patients stones were found after cholecystectomy. In the remaining 3 patients there was a high operative risk. No serious complications occurred. Consequently the removal of choledocholithiasis by endoscopic papillotomy is an alternative to traditional treatment.

Adult↗
PubMed1975

Endoscopic retrograde brush cytology (ERBC) of the biliary and pancreatic ducts.

A new device with a brushing tube that can be introduced through the biopsy channel of the duodenoscope (Olympus JF B) used for cannulation of the papilla of Vater is reported. In 17 patients in whom ERCP had demonstrated ductal abnormalities, an endoscopic retrograde brush cytology (ERBC) was performed. A cytological diagnosis of malignancy was made in 8 patients and a possible malignancy in 2 cases. Seven cases were operated upon, and a malignant tumor was found in 6. In one case a malignant tumor was found at autopsy. Histological examination was performed in 6 cases and showed adenocarcinoma in all.. Two patients with malignant cells and ERCP-findings of suspected pancreatic carcinoma were not operated upon. The tumours were localized in 1 case to the papilla of Vater, in 2 to the biliary duct, in 4 to the pancreatic head, and in 2 cases to the pancreatic corpus. No complications occured. It is concluded that this technique provides information supplementary to that of other diagnostic procedures.

Adenocarcinoma↗