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Biomedical subjects

M P Cheren'ko

Publications and source records attributed to M P Cheren'ko.

At least 19 recordsLinked to original sources

[Dynamics of morbidity of the thyroid gland cancer. Evolution of views on its diagnosis and treatment (according to material of the clinic for 50 years)].

For 50 years 603 patients with the thyroid gland cancer were operated on, to whom 715 operative interventions were done. Before the Chernobyl disaster 395 patients were examined, after her--208. Differentiated forms of the thyroid gland cancer were diagnosed in 97.3% of patients, including papillary one--in 83.3%, follicular--in 14%. After the Chernobyl disaster the thyroid gland cancer diagnosis had improved significantly, it had become revealed on early stage. There were 5.6% patients with cancer operated for the thyroid gland diseases for 50 years (5%--before the disaster and 7.8%--after her). The clinical course of differentiated thyroid gland cancer permits to perform organpreserving operation no less than hemithyroidectomy in patients with T1-2N0M0 stage of the disease. The five-year survival index of patients with differentiated cancer had constituted 89%, the ten-year one--84%.

Carcinoma↗

[Pathogenesis, surgical treatment and prophylaxis of goiter recurrence].

The causes of the nontoxic goiter recurrency occurrence, the prophylactic methods and the results were analysed according to the data obtained while examination and treatment of 115 patients. The autoimmune damage of a leaved thyroidal gland remnant constitutes one of the causes of the genuine recurrency of goiter.

Adult↗

[The immune status indices of patients with local purulent necrotic lesions].

Hypoproteinemia, the lowering of albumin-globulin coefficient, IgG and T-suppressors level, the circulating immune complexes contents increase were revealed while the immunological state investigation in 100 patients with purulent wound. The results obtained witness the necessity of application of immunostimulating and antimicrobic methods, which do not influence an organism negatively (fluorochinolones, for example) in treatment of patients with purulent-necrotic infection.

Abscess↗

[The diagnosis and surgical treatment of a lateral cyst and fistula of the neck].

Surgical treatment was performed in 66 patients with lateral cyst and 23 with congenital single brachiogenic cervical fistula. In 14 patients, a cyst was complicated by a cervical phlegmon, 17 had a complete fistula, 6--incomplete one. In cyst diagnosis, the clinical signs and puncture of a cyst is of crucial importance, in fistula diagnosis--its connection with the pharynx--introduction of a dye. Removal of the uncomplicated cyst, spontaneously opened cyst-phlegmon (in 58 patients) and fistula (in 20) was performed with the use of the most cosmetic oblique-transverse incision. A lateral cyst often becomes infected and is subject to removal immediately alter establishment of the diagnosis. It is preferable to operate the patients with a lateral congenital cervical fistula non-complicated by infection when they are under school age.

Adolescent↗

[Preoperative preparation and surgical treatment of elderly and very old patients with abdominal hernia].

On the basis of analysis of the results of treatment of 312 elderly and senile patients with abdominal hernia, it was established that performance of adequate preoperative preparation permitted considerable extension of indications for the operation. Contraindications for surgical treatment of such patients should be established after performance of preoperative preparation with regard for indices of external respiration and hemodynamics.

Aged↗

[Characteristics of diagnosis and surgical treatment of median cysts and fistulas of the neck].

On the basis of the experience with treatment of 219 patients with middle cysts and fistulas of the neck, the authors consider the causes, diagnosis and differential diagnosis of the disease. Operated on were 218 patients. An excellent result of treatment was noted in 206 (94.5%) of them. Twelve patients developed a disease recurrence. They underwent the reoperation. Technique of operation is described in detail. It is stressed that a good result is possible only in removal of a cyst (fistula) with resection of the hyoid bone body.

Adolescent↗

[The so-called goiter of the accessory thyroid glands].

In the period of 1954-1966, 74 patients were operated on for goiter of the accessory thyroid glands (GATG). Of them, in 45 in histologic investigation, papillary adenoma or microfollicular, less often parenchymatous, goiter were revealed, in 29--papillary cancer or papillary adenoma at the state of malignization. The long-term follow-up (up to 30 years) of the patients with reoperations for GATG recurrences, or subsequent development of a "goiter" has shown that GATG presented a metastasis of papillary thyroid cancer into the lateral lymph nodes of a neck. At operation, the revision of a thyroid gland with intervention on it is mandatory. The term GATG we haven't used from 1966.

Adolescent↗

[Characteristics and surgical treatment of nodular goiter in middle-aged and aged patients].

Four hundred and two elderly and senile patients with nodular goiter were operated on. In most of them, hypothyrosis (decreased triiodothyronine level and increased thyrotropic hormone content in the blood) was revealed; in all--concomitant diseases (2.9 per a patient) and immunologic disorders; in 47%--cervico-retrosternal location of a goiter. In 65.2% of goiter preparations, the degenerative-sclerotic changes were found, in 33%--lymphoid infiltration of stroma, in 18.7%--malignant growth. Operation is the most effective method of treating elderly and senile patients with nodular goiter. It should be of little trauma relative to normal parenchyma.

Age Factors↗