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Biomedical subjects

M P De Padova

Publications and source records attributed to M P De Padova.

At least 19 recordsLinked to original sources

Generalized lichen nitidus with oral and nail involvement in a child.

The generalized form of lichen nitidus (LN) with oral and nail changes is extremely rare in childhood. We report a 10-year-old boy with generalized LN associated with oral involvement and onychodystrophy. Oral lesions showed yellowish papules on the gums. The nails had longitudinal striations and pits on the finger-nails, and transversal ridging of the big toes was found. Cutaneous and mucosal lesions as well as onychodystrophy spontaneously cleared within 8 months.

Child↗

Nail involvement in lichen planopilaris.

A patient with lichen planopilaris with peculiar leukonychia is described. The histologic findings from examination of the nail biopsy specimen are discussed.

Humans↗

Therapies versus placebo in the treatment of patchy alopecia areata.

We report the results of a controlled trial on 119 patients affected by patchy alopecia areata involving less than 40% of the scalp. The statistical analysis showed no differences between the results obtained using squaric acid dibutylester, diphencyprone, minoxidil, and placebo in the treatment of this form of alopecia.

Adolescent↗

Retinal pigment epithelium function in alopecia areata.

Electroretinography (ERG) and electro-oculography (EOG) were performed in 98 patients affected by alopecia areata (AA) free from ophthalmologic disorders, and in 40 healthy subjects, in order to evaluate whether or not the retinal pigment epithelium of AA patients shows bioelectrical changes. ERG was normal. EOG, on the contrary, showed a significantly depressed mean value in the AA patient group. Furthermore, depressed EOG occurred more frequently in patients affected by alopecia totalis or universalis as compared with multiple patchy alopecia. These findings prompt the authors to believe that the melanocytes may play a prominent part in the pathogenesis of AA.

Action Potentials↗