Biomedical subjects

M P Engelmeier

Publications and source records attributed to M P Engelmeier.

17 recordsLinked to original sources

PubMed1987

Visual hallucinations in ophthalmology.

Forty-three patients with severe visual impairment due to bilateral eye disease were assessed for visual hallucinations, 28 of them after eye surgery. Ages ranged between 65 and 93 years and none of the patients had any psychiatric disorder. Five of the 43 patients were diagnosed as cases with Charles Bonnet syndrome reporting visual hallucinations that had developed in the course of sight deterioration. There was strong indication that sensory deprivation was an essential pathogenetic factor for this phenomenon. Three of the 28 patients assessed following eye surgery who had no history of hallucinatory phenomena experienced visual hallucinations on the 2nd postoperative day without showing any other psychiatric symptoms. The various conditions associated with visual hallucinations are discussed that may be of relevance to the ophthalmologist.

Aged↗

PubMed1986

Clinical application of event related potentials in patients with brain tumours and traumatic head injuries.

Event related potential recording and psychometric evaluation of cognitive impairment were carried out on 21 patients with brain tumours, 21 patients with severe head injuries and 24 controls. The tumour and trauma patients who met the psychometric inclusion criteria for dementia, but not the non-demented patients, had significantly longer N2 and P3 latencies than the controls. In assessing individual patients P3 latency correctly differentiated between demented and non-demented patients in 81% of cases (for N2 latency 77%). Particularly P3 latency may provide a practical and objective measure of mental impairment in neurosurgical disorders producing dementia. Marked asymmetry in N2 and P3 amplitudes between hemispheres was observed in a number of cases. No significant relationship was found between diminution of N2 and P3 components and side of lesion.

Adult↗

PubMed1986

[Event-related brain potentials and intellectual impairment--a study in patients with brain tumor and craniocerebral trauma].

Event-related potential recording (component N1, P2, N2, and P3) and neuropsychological assessment of cognitive impairment were carried out on 15 patients with brain tumour, 15 patients with severe head injury and 24 controls. The tumour and trauma patients had significantly lower psychological test scores, smaller N1 amplitudes and longer N2 and P3 latencies than normals. For the tumour and trauma patients significant correlations were found between N2 and P3 latency and the Mini-Mental State test and memory tests. For individual patients abnormally increased N2 and P3 latency was found to occur in association with abnormally reduced neuropsychological test scores. N2 and P3 latency proved the only electrophysiological variables examined which provided a measure of cerebral functioning correlating with the psychometric variables. N2 and P3 latency may be regarded as a useful diagnostic test for cognitive impairment especially in patients with motor handicaps, to whom neuropsychological tests cannot be administered.

Adult↗

PubMed1982