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Biomedical subjects

M P Fleming

Publications and source records attributed to M P Fleming.

17 recordsLinked to original sources

Effects of varying scoring rules of the Clinician Administered PTSD Scale (CAPS) for the diagnosis of PTSD after acute burn injury.

The Clinician Administered Posttraumatic Stress Disorder Scale (CAPS) enables quantification of the severity of each of the 17 posttraumatic stress disorder (PTSD) symptoms. Blanchard and colleagues (1995) have documented variation in rates of PTSD among survivors of motor vehicle accidents depending on the CAPS scoring rule used. This report examines the effects of varying the scoring rules of the CAPS on rates of acute PTSD symptoms in hospitalized burn patients. Changing from the most liberal to the most conservative scoring rule resulted in a change in diagnosis of acute PTSD from 25% of 32% of the sample. The variation documented in this study and others has implications for a range of issues, including rates of PTSD in epidemiological studies, treatment outcome research, and forensic evaluations.

Acute Disease↗

A telemedicine consultative service for the evaluation of patients with urolithiasis.

OBJECTIVES: A 6-month pilot teleconsultative project linking Georgetown University Medical Center (GUMC) in Washington, DC, and City Hospital in Martinsburg, West Virginia, 90 miles away, was designed to assess the effectiveness of telemedicine on the clinical decision-making process for patients with urolithiasis. METHODS: The telemedicine system designed and tested for this project was based on a PC-based platform. Videoconferencing and review of the patient's imaging studies were performed over an Integrated Service Digital Network (ISDN) with 3 Basic Rate (BRI) ISDN lines providing a 336-kilobytes/s bandwidth through an Inverse Multiplexor (IMUX). Treatment options were recorded for the clinical trial group and a simulated study group by the consulting urologist after the initial telephone consultation, after the telemedicine consultation, and after examination of those patients transferred to GUMC. RESULTS: A total of 32 telemedicine consultations were performed: 14 in the clinical trial group and 18 in the simulated study group. The recommendation of the consulting urologist at the tertiary center was altered in 12 patients (37.5%) after the telemedicine consultation compared with the recommended treatment after the initial telephone consultation. CONCLUSIONS: In the evaluation of patients with urolithiasis, this telemedicine application enhanced the clinical decision-making process by allowing for improved quality of care through immediate access and effective transfer of information between the referring urologist, the patient, and the stone center specialist.

Adult↗

Association of Campylobacter jejuni with enteritis in dogs and cats.

Campylobacter jejuni was recovered from 59 of 505 (11.7 per cent) dogs with diarrhoea as compared with only two of 122 (1.6 per cent) dogs without diarrhoea. However, there was no significant difference between campylobacter isolations from 142 cats with and without diarrhoea. C jejuni infections were commonly associated with chronic diarrhoea in both species and appropriate therapy abolished clinical signs and excretion of the organism in faeces in most cases. C jejuni may be responsible for some forms of enteritis in dogs and cats and is a zoonosis in which the companion animal may be the vector.

Animals↗

Trimethoprim-resistance and its transferability in E. coli isolated from calves treated with trimethoprim-sulphadiazine: a two year study.

Regular examination of rectal swabs revealed the presence of very low numbers of trimethoprim resistant Escherichia coli in the faeces of 10 batches of calves successively reared in the same shed and none of these strains transferred trimethoprim resistance to E. coli K12. All the calves had received oral doses of 30 mg/kg day of trimethoprim-sulphadiazine for 5 consecutive days. From two subsequent batches of calves reared in the same shed, however, several isolations were made of E. coli with transmissible R factors determining trimethoprim and streptomycin resistance. Shortly before these strains were detected, isolations of E. coli with similar properties had been made from other calves, in a different shed, which had been fed much higher doses of trimethoprim-sulphadiazine. Serological evidence indicated that all the E. coli isolated carrying this R factor belonged to the same strain, which had apparently spread from the second shed to the first. No evidence of ;in vivo' transfer of the R factor to other enteric bacteria was obtained.

Agglutination Tests↗

Trimethoprim resistance determined by R factors.

R factors conferring a high level of resistance to trimethoprim have been identified in one strain of Escherichia coli and one of Klebsiella aerogenes, both isolated from infected urines.

Anti-Bacterial Agents↗