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Biomedical subjects

M P Gangai

Publications and source records attributed to M P Gangai.

At least 19 recordsLinked to original sources

Adenocarcinoma of the prostate: results of routine urological screening.

The results of routine urological screening of 2,005 men between 40 and 70 years old were reviewed. Digital rectal examination was used to screen for adenocarcinoma of the prostate. Of 65 nodules detected 17 proved to be adenocarcinoma. Clinical staging revealed no evidence of metastases in all but 2 patients but pathological (surgical) examination resulted in upstaging of disease in 66 per cent of the patients who underwent an operation. Digital rectal examination proved to be an insensitive screening device with poor predictive value. The use of adjunctive screening tools for detection of adenocarcinoma of the prostate is suggested.

Adenocarcinoma↗

Peyronie's plaque: excision and graft versus incision and stent.

Nineteen patients with Peyronie's plaque unsuccessfully treated conservatively were considered surgical candidates. Although all patients had erections intercourse was functionally difficult to impossible for most. Only 30 per cent of the patients who underwent plaque excision and grafting became sexually functional postoperatively. Placement of penile prostheses appears to be the most secure method to rehabilitate the male patient who has become a sexual cripple secondary to Peyronie's plaque.

Adult↗

The incidence of bladder cancer after cyclophosphamide therapy.

The records of 19,082 patients with non-uroepithelial cancers were reviewed to determine the incidence of de novo bladder cancer in patients treated with cyclophosphamide versus patients not treated with this drug. A 9-fold increased incidence of bladder cancer was found in the cyclophosphamide-treated group.

Adult↗

Surgical injury to ureter.

The incidence of surgical injury to the ureter varies from as low as 0.5% to as high as 30%. By being aware of various pitfalls in prevention, recognition, and treatment, the operating surgeon may perhaps minimize the incidence of surgical injuries to the ureter or their sequelae. The authors' experience with twenty-four surgical ureteral injuries is discussed and 5 cases are reported. In spite of a thorough knowledge of embryology, anatomy, and pathology predisposing to ureteral involvement, the possibility of ureteral injury must always be kept in mind.

Abortion, Therapeutic↗

Testicular biopsy: sperm antibodies.

No circulating sperm-agglutinating or sperm-immobilizing antibodies were demonstrated in oligospermic or azoospermic men up to 14 days following bilateral testicular biopsies. Possible reasons for this lack of antigen-antibody response are discussed.

Adult↗