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Biomedical subjects

M P Sharma

Publications and source records attributed to M P Sharma.

At least 73 records · Page 4Linked to original sources
PubMed1989

Poor response to long-term albendazole therapy of hydatid liver cysts.

Seven patients with uncomplicated hepatic hydatid cysts (Echinococcus granulosus) were treated with albendazole 10 mg/kg/day for 2-6 months (mean 4 months). Serial sonographic evaluation showed reduction in cyst size in only 1 patient (the anteroposterior diameter decreased from 16.5 cm to 4.9 cm). Therapy in this patient was discontinued after 4 months due to development of jaundice. Albendazole appears to have a limited role in the treatment of hydatid disease of the liver.

Adult↗
PubMed1989

Serum alpha-feto protein in amoebic liver abscess.

Serum alpha-feto protein (AFP) levels were determined using a sensitive and specific ELISA technique in healthy persons (40), patients with amoebic liver abscess (ALA, 70) and hepatocellular carcinoma (HCC, 20). The AFP levels in normal persons ranged between 0 to 20 ng/ml. Most of ALA patients had AFP levels in the normal range; only a small proportion (14.3%) showed elevated levels (range 20-75 ng/ml). Sera from HCC patients had significantly high AFP values in the range of 25 to 340 ng/ml as compared to normal controls and ALA patients. An analysis of serial samples from 10 ALA patients in convalescent phase showed no difference in AFP level during acute and convalescent phase of infection.

Carcinoma, Hepatocellular↗