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Biomedical subjects

M P Stearns

Publications and source records attributed to M P Stearns.

17 recordsLinked to original sources
PubMed1995

Bleeding after tonsillectomy in severe von Willebrand's disease.

A case is reported of a HIV-positive patient with severe von Willebrand's disease describing the bleeding complications during and after tonsillectomy. This patient underwent surgery for asymmetrical tonsillar hypertrophy. The tonsils were spontaneously haemorrhaging and there therefore was a suspicion of neoplasia. Despite close cooperation between the ENT Department and the Haemophilia Centre, involving per-operative Factor VIII monitoring and replacement, the patient suffered both protracted primary and secondary haemorrhages. We report this as a cautionary tale as our previous experience with mild to moderate haemophilia has been uncomplicated, but on this occasion there was massive haemorrhage. We feel that tonsillectomy should not be undertaken in a patient with a severe bleeding disorder without an absolute indicate.

Adult↗
PubMed1994

Orbital complications of sinusitis: avoid delays in diagnosis.

Orbital cellulitis and abscess formation are uncommon complications of sinusitis. Early diagnosis and treatment are important to prevent blindness and intracranial complications. We present four consecutive cases referred over 2 years which demonstrate how diagnostic delays may occur and suggest a protocol to avoid similar delays.

Abscess↗
PubMed1990

Oncocytoma of the larynx.

A case of oncocytoma of the larynx is presented. These lesions are rarely found in the larynx, and have been more commonly described in the salivary and thyroid glands. The histopathological diagnosis is often difficult and the light microscopy can be unreliable for oncocytic lesions. For a more accurate definition of these tumours, the use of histochemical stains together with electron microscopy are advocated. With adequate surgery, the prognosis is excellent, and tumours are unlikely to recur. This paper discusses the management of a patient with a benign oncocytoma of the true vocal cord, and presents a review of the world literature.

Adenoma↗
PubMed1990

Haemangiosarcoma of the maxillary antrum.

Angiosarcomas are extremely rare in the head and neck and the histological diagnosis is often difficult. We present a case of a haemangiosarcoma of the maxillary antrum in a 33 year old male. The histological diagnosis and subsequent management are discussed.

Adult↗
PubMed1987

Reconstruction of the middle third of mandible.

The radial forearm flap is established as a suitable method of providing bone with soft tissue lining or skin cover in reconstruction of the mandible. A simple and effective method of modelling the radius to provide the appropriate contour to the anterior arch of the mandible is described.

Humans↗
PubMed1983

The effect of irradiation on nerve regeneration.

Nerve grafts were performed on rat sciatic nerves at varying intervals after the graft bed had been irradiated. The functional repair was assessed electrophysiologically. Five groups of animals were used with the pre-operative interval varying from 1 to 8 weeks. No difference was found in the success of the nerve graft in any group.

Action Potentials↗
PubMed1982

The effect of irradiation on nerve grafting.

The purpose of this study was to investigate the effect of pre-operative radiotherapy on nerve grafting, using the rat sciatic nerve as an experimental model. Two groups of 10 rats were used, one group irradiated, the other not. In each rat a 5 mm section of one sciatic nerve was excised then replaced and sutured into position. Nerve regeneration was investigated by expressing the area of the mass action potential in the regenerated nerve as a percentage of the mass action potential in the contralateral intact nerve. A significant difference (P less than 0.01) in nerve regeneration was found between the irradiated and non-irradiated animals. In the irradiated group only two animals achieved more than 20% nerve fibre regeneration whilst in the non-irradiated group all but two animals achieved greater than 20% regeneration. These results suggest that pre-operative irradiation has an adverse effect on nerve regeneration.

Animals↗
PubMed1981

Preservation of the accessory nerve in block dissection of the neck.

The signs and symptoms resulting from division of the accessory nerve are discussed. The anatomical arguments for conservative neck dissection are also described. A method of preserving the nerve during radical neck dissection is described. A comparison of the symptomatology and functional results of two groups of patients follows, one group having had preservation and the other having had conventional neck dissection. It was shown that the group with conservative neck dissection had no symptomatic or functional abnormalities.

Accessory Nerve↗
PubMedDate not supplied

Age-related changes in the epithelium of the monkey larynx.

An experiment was designed to measure the area of subglottic squamous epithelium in a group of 14 adult monkeys. The animals were much older than any so far available for medical research. The larynges were strained using pyronin Y, which stains respiratory epithelium magenta and squamous epithelium pale pink. The areas of squamous epithelium inferior to the free margin of the vocal cord were measured. The results showed that the subglottic epithelium increased with age (r = +0.61, p = less than 0.05). This finding may have importance in the staging of laryngeal carcinoma.

Aging↗