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Biomedical subjects

M Pérez García

Publications and source records attributed to M Pérez García.

13 recordsLinked to original sources

[Cryotherapy with nitrous oxide in primary care].

OBJECTIVE: To study the efficacy, tolerance and safety in primary care of the cryotherapy technique using nitrous oxide. Design. Descriptive, observational and transversal study. SETTING: Mariñamansa-A Cuña Health Centre, Ourense. PARTICIPANTS: All the patients who consulted for cutaneous lesions caused by cryotherapy between March and April 2000 (n=130). MAIN MEASUREMENTS: Age, sex, diagnosis, location, size of lesion, duration of application of the cryogenic agent, previous treatment, side-effects observed, and evolution of the lesion. RESULTS: Mean age was 36.65 (95% CI, 32.57-40.74), of whom 53.8% (95% CI, 44.80-62.50) were women. The most common lesions were common warts (68.5%), actinic Keratosis (12.3%) and plantar warts (7.7%). We found that most lesions were located on an upper limb (50.8%). The mean size of lesions was 8.65 mm2 (95% CI, 4.50-12.80). 69.7% of warts were scraped prior to cryotherapy; and 16.2% received prior keratolysis. We found no side-effects in 32.3% of the patients; the commonest side-effect detected was blisters. Mean number of cryotherapy sessions was 2.82 (95% CI, 2.39-3.29). The technique was tolerated well in 83.8% of cases. We found total cure in 87.7%. Most of the cutaneous lesions that failed were common warts. CONCLUSIONS: Nitrous oxide is effective in most lesions caused by cryotherapy. The technique is tolerated well, can be handled easily and can be used in primary care.

Adult↗

[Assessment of drug treatment for hypertension in a health centre as a function of associated chronic pathologies and degree of control of the hypertension].

OBJECTIVE: To assess the suitability of whatever hypertension medication is prescribed for the associated pathology in each patient, and to analyse the monitoring of blood pressure figures. DESIGN: A cross-sectional descriptive study.Setting. Urban health centre. PATIENTS: The target population were the hypertension patients being treated with medication and monitored at the health centre. Stratified random sampling by quotas of the total number with hypertension was performed. The sample numbered 219 patients. MEASUREMENTS: The clinical history of each patient selected was reviewed. To evaluate the hypertension treatment, we established three levels of suitability with regard to the accompanying pathology of each patient (suitable, intermediate, unsuitable), using the 1999 Hypertension Protocol of the Spanish Society of Family and Community Medicine. RESULTS: Out of 219 cases, treatment was suitable in 71 (32.4%), intermediate in 91 (41.6%), and unsuitable in 57 (26%). The most frequently indicated drug group was the angiotensin converting enzyme inhibitor (ACEI) group and, jointly, ACEI and diuretics. Regarding the monitoring of blood pressure: 66.5% had very good monitoring, 23.2% partial and 9% poor. CONCLUSIONS: Most treatments are at an intermediate level of suitability: without beneficial or undesirable effects on the associated pathology. This makes us think we need to optimize the drug indicators for hypertension.

Aged↗

Variables modulating stress and coping that discriminate drug consumers from low or nondrug consumers.

The present study assesses how certain stress and coping variables relate to drug use. A total of 124 subjects (85 men, 39 women) took part. They were divided into two groups: consumers and low or nonconsumers. Results indicate that consumers show significantly lower scores in self-control than low or nonconsumers. This research is of interest because it analyzes the relationship among assertiveness, self-control, self-efficacy, and drug use. We consider it worthwhile to take these variables into account when planning prevention programs.

Adaptation, Psychological↗

[Alterations in the decision making processes linked to the ventromedial prefrontal cortex in drug-abusing patients].

INTRODUCTION: The somatic marker hypothesis proposes that somatic signals guide the decision making processes in an adaptive sense for the organism. The processing of these somatic signals is linked to the ventromedial prefrontal cortex activity. The influence of somatic markers on decision making processes has been studied by means of the 'gambling task' (GT). Several studies using the GT in substance abusers have showed the existence of decision making impairments in these patients. AIMS: To examine the performance in the GT of a Spanish sample of substance abusers; and to study the influence of clinically relevant variables: type of substance, years of abuse and abstinence period on GT performance. PATIENTS AND METHODS: 106 substance abusers patients during the dishabituation phase participated in the study. We administered a computerized version of the GT in a single individual session. We used descriptive analyses to study the patients' performance in the GT. Next we carried out multiple regression analyses to study the influence of the clinical variables on the GT performance. RESULTS: A 76.4% of the sample patients showed impairments in the decision making processes measured by the GT. None of the clinical variables significantly predicted performance in the task. CONCLUSIONS: These results suggest the existence of decision making impairments in substance abusers that may be related to pre morbid alterations, or to a neurotoxic effect of drugs of abuse on the activity of the ventromedial prefrontal cortex.

Adaptation, Psychological↗

[Assessing the sexual functioning of chronic inpatients at a psychosocial rehabilitation unit].

INTRODUCTION: Most chronic inpatients at psychosocial rehabilitation units in our environment suffer some kind of psychosis. The sexual function in these patients has been studied little and the rate of sexual dysfunction studied in similar populations is very high. OBJECTIVES: To assess the sexual function of the inpatients at a psychosocial rehabilitation unit and to measure other clinical and demographic variables of these patients. METHODS: A sample of 46 inpatients was obtained in the psychosocial rehabilitation unit. Sexual function was assessed using the Changes in the Sexual Function Questionnaire (CSFQ). RESULTS: A high number of patients scored below the minimal normal score in the CSFQ (males: 87.9%; women: 87.5%). This implies a high prevalence of sexual dysfunction. CONCLUSIONS: The high percentage of patient with sexual dysfunction can be in connection with the severity of the disease that these patients suffer and with the side effects of the medication.

Adult↗