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Biomedical subjects

M Pérez-Romero

Publications and source records attributed to M Pérez-Romero.

6 recordsLinked to original sources

[Study of the brachial plexus by magnetic resonance].

OBJECTIVE: Magnetic resonance (MR) is considered to be the best method available at present for diagnosis of lesions of the brachial plexus. In this study we analyze our experience in patients with pathology of the brachial plexus. MATERIAL AND METHODS: Between August 1991 and March 1997 we did magnetic resonance studies on 42 patients with pathology of the brachial plexus. Our protocols included T1, T2 axial spin-echo sequences with 5 mm cuts and coronal echo of a T1-3D gradient with 2 mm cuts, together with a T1 coronal spin-echo, with cuts 2 mm in width. RESULTS: The causes found were: traumatic 16 patients (38%), pathology of bone 2 (4.7%), 19 tumours (45.2%) with breast cancer being commonest, and no obvious aetiology in 5 (11.9%). CONCLUSIONS: MR is the technique of choice for study of pathology of the brachial plexus of traumatic or tumour origin. In some patients, 11.9% in our series, no aetiology could be detected using MR.

Adolescent↗

[Self-limited steatorrhea and chronic autoimmune hepatitis type I. The Group for the Study of Viral Hepatitis and AIDS].

Active chronic hepatitis is very infrequent in Spain. Its autoimmune pathogenesis is supported by the coexistence of autoimmune features, its usually good response to immunosuppressive treatment and the frequent coexistence of other processes of autoimmune etiology. The infrequent cases of steatorrhea observed may usually be found in the presence of severe colostasis or in association with other diseases such as celiac disease. The presence of sever anemia is also infrequent being observed on hemolysis of digestive bleeding. A case of autoimmune type I chronic hepatitis observed in a 14-year old woman presenting as acute hepatitis associated to severe anemia (Hb, 6,3 g/dl) and self-limited steatorrhea independent of the clinical course of the hepatic picture (stool fats of up to 100 g/24 h) with no evidence of hemolysis, digestive bleeding, obvious colostasis, drug ingestion or demonstrable intestinal or pancreatic disease. The coexistence of these unusual findings led the authors to report this case.

Adolescent↗

Hepatitis C virus infection among sexually promiscuous groups and the heterosexual partners of hepatitis C virus infected index cases.

To define the role of sexual transmission in the spread of hepatitis C virus (HCV) infection, a seroprevalence study of antibodies against HCV was performed in populations at high risk for sexually transmitted diseases. Subjects included 310 female prostitutes, 88 clients of prostitutes, 168 homosexual men and 147 stable heterosexual partners of index cases reactive for anti-HCV (98 of whom were partners of drug addicts coinfected with HCV and human immunodeficiency virus [HIV]). All subjects denied prior transfusion or intravenous drug use. Controls were 400 voluntary blood donors selected randomly from first-time donors. The prevalence of anti-HCV by enzyme immunoassay, confirmed by a second-generation recombinant immunoblot assay, was 6.4% in prostitutes, 6.8% in clients of prostitutes, 4.2% in homosexual men, 7.4% in heterosexual partners of index cases and 1.2% in random donors. However, the anti-HCV prevalence in stable heterosexual partners of HCV-positive/HIV-positive index cases was 2.2 times higher than in stable heterosexual partners of index cases reactive for anti-HCV only (9.2% vs. 4.1%), and sexual partners of index cases coinfected with HCV and HIV were almost three times more likely to be infected with HIV than with HCV (25.5% vs. 9.2%). These data suggest that HCV infection may be sexually transmitted but with low efficiency and that this efficiency could be increased in the presence of coexistent HIV infection in the index case.

Adolescent↗

[Neuroepithelial tumors in the pediatric population].

We have studied the neuroepithelial tumors in childhood, about their epidemiological, clinical and histological aspects, the macroscopic tumoral structure and the findings obtained by magnetic resonance imaging. We stress the differential diagnosis features among the various tumoral types, based on bibliography and our own clinical experience.

Astrocytoma↗

[Normal myelination patterns].

The MR images obtained of brain during the process of myelination taking place from birth to 2 years of age are analyzed. Basically, the study focuses on the changes in signal intensity experienced by the elements of the brain in the different sequences, consisting in an increase (T1 weighted sequence) or decrease (T2 sequences) in the signal. The chronological evolution of these changes is compared with the classic myelination pattern, described prior to the development of MR, based on necropsies. Also assessed were the progressive changes in the signals of the gray and white matter, reflecting their hydric contents, throughout the period of maturation of the brain structures. It is concluded that MR imaging is presently the diagnostic method of choice in the monitoring of myelination. MR spectroscopy studies offer important perspectives for assessment and follow up of this process from the metabolic point of view.

Aging↗