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Biomedical subjects

M Pacheco

Publications and source records attributed to M Pacheco.

68 records · Page 4Linked to original sources
PubMedDate not supplied

[Congenital atonic-sclerotic muscular dystrophy (Ullrich disease)].

A case of congenital atonic-sclerotic muscular dystrophy is described, with a combination of proximal joint rigidity and distal hypotonia and hyperextensibility, besides torticollis and kyphoscoliosis. These severe congenital defects usually prevent walking and are followed by chronic respiratory insufficiency, with a fatal outcome in the long term. An autosomal recessive type of heredity is implied. There is not sensory or intellectual impairment, therefore it can be distinguished from other congenital muscular dystrophies, that usually have CNS abnormalities associated.

Follow-Up Studies↗
PubMedDate not supplied

[Gastric mucosa injuries in portal hypertension].

Portal Hypertension (PH) was diagnosed in 114/4145 patients (p) evaluated by upper gastrointestinal endoscopy during 1991-92 (2.75%). Portal hypertensive gastropathy (PHG) was found in 39.47% p. Mild PHG was observed in 82.22% and esophageal varices grade was directly correlated to PHG presence. This is a new entity to be considered because of its bleeding possibility in PH patients.

Adolescent↗
PubMedDate not supplied

[Helicobacter pylori eradication heals the duodenal ulcer. Randomized, simple, and controlled study with omeprazole].

60 patients with Helicobacter pylori (Hp) infection and duodenal ulcer (DU) were randomized to received either: I) Two weeks of bismuth subcitrate, metronidazole and amoxicillin (TG) or II) Omeprazole for four weeks (OG). Endoscopy and antral biopsies were done at entry and four weeks after treatment, control endoscopy was performed 2-4-8 and 12 weeks after inclusion in the trial. Healing was similar in both groups at two four weeks. At twelve weeks DU recurred in OG 65% vs 13.36% in TG and Hp infection was present. Our results showed that Hp eradication healed DU in a similar rate than Omeprazole providing further evidence of a causal link between Hp infection and duodenal ulcer.

Administration, Oral↗