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Biomedical subjects

M Palomar de Luis

Publications and source records attributed to M Palomar de Luis.

4 recordsLinked to original sources

[The recurrence of colorectal cancer and blood transfusion].

Report of a retrospective study on 303 patients operated from colorectal carcinoma to whom colonic resection was done in B and C stages of Astler-Coller's classification. The aim was to try to find a relation between blood transfusion and colorectal carcinoma recurrence. The statistical study is made with the program LOGIT, studying the surgical incision, evolutive stage and blood transfusion variables. The significant contribution of each variable in the occurrence of recurrence is studied with the Wald Test. As a result it can be deduced that the prognosis of colorectal cancer is influenced by three factors: the evolutive stage, the surgical incision (1.87 times more frequent for the abdomino-perineal) and the transfusion of more of three units of blood in the perioperative period which multiplies by 2.85 the risk of recurrence of colorectal carcinoma. In our hospital almost exclusively red cell concentrates (including red cells, white cells and minimal fraction of plasma), are transfused; possibly the white cells are responsible for the recurrence.

Adenocarcinoma↗

[Spontaneous biliodigestive fistula].

A retrospective study was made of 23 cases of spontaneous biliodigestive fistulae collected from bile tract surgery performed in our center from 1979 to 1987, representing 1.05% of the total number of cases. The etiology was cholelithiasis in almost all cases and the most frequent connection was to the duodenum. Forty-eight percent of the cases presented as biliary ileus. In each case surgery depended on the etiology, clinical manifestations and status of the patient. The mortality was 8.7% and the morbidity 52%. Results are analyzed and a bibliographic review of the topic is offered.

Adult↗

[Prognostic factors in colorectal cancer].

We present a retrospective study of 208 colorectal cancers, 131 of them followed during more than 5 years. Overall survival was 38%. We have tried to correlate clinical findings with prognosis and survival. The analyzed parameters have been the following: age, sex, site and size of the tumor, time and cause of surgical treatment, stage of the lesion, cytologic grade of differentiation of the tumor, delay between the presenting symptom and surgery, surgical procedure, local invasion and number of positive lymph nodes. The results show that the main factors related to prognosis are local extension through the intestinal wall and the presence of positive lymph nodes (particularly if more than 4) and, of course, distant metastases.

Adenocarcinoma↗

[Colonic surgery in the elderly. Comparative study with other age groups].

From 1980 to 1986, 569 patients with colonic disease underwent surgery in the General Surgery Service of "Nuestra Sra. de Aránzazu" Hospital, 131 of them over 75 and representing 23% of the total. In this group, neoplasms were the most common lesion, for a total of 108 cases (83.2%). Among nontumoral diseases, half corresponded to diverticula. Colonic surgery was practiced as an emergency in 35.87% of the cases and in 72.7% of the non-neoplastic lesions, with an overall operative mortality of 28 patients (21.37%). We analyze the distribution of the different lesions of the colon, the urgency of the operation and operative mortality as related to age, evaluating the limitations in elderly patients and their increased surgical risk.

Age Factors↗