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M Panjabi

Publications and source records attributed to M Panjabi.

21 records · Page 2Linked to original sources
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The effect of tourniquet pressure on muscle function.

The adverse effects of excessive tourniquet pressure on underlying muscle were studied using a cat model. A direct effect of the magnitude of tourniquet pressure on the degree of muscle disability was observed. The effect of direct pressure on the muscle may contribute to the postoperative weakness seen in the quadriceps muscle. Our data, in conjunction with the results of other studies that correlate certain tourniquet times and pressures with potential adverse effects, suggest that the selection of an appropriate tourniquet pressure and duration will minimize the development of clinically significant complications.

Animals↗
PubMedDate not supplied

1981 Nicolas Andry Award. The relationship of mechanical trauma and the early biochemical reactions of osteoarthritic cartilage.

Using a computerized pendulum device for delivery of a moderate, reproducible impact on the surface of canine femoral cartilage, the lipids of the cartilage were analyzed by gas chromatography, and a four-fold increase in arachidonic acid was found in the phospholipid pool, as compared with controls. This is the first evidence presented thus far which clarifies the link between mechanical injury and the early biochemical changes of the osteoarthritic process. Electron microscopy of impacted cartilage cells showed an increase in lipids and microtubules and cytoplasmic derangement. There was a brief rise in hexosamine content soon after impaction, followed by a trend toward loss.

Animals↗