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Biomedical subjects

M Pankratov

Publications and source records attributed to M Pankratov.

3 recordsLinked to original sources

Wide-angle optical model of the eye.

There are two approaches to the design of a wide-angle optical model of the eye. One approach is based upon data on biological and physical characteristics of the eye (cornea, crystalline lens) collected from the literature or from in vivo or in vitro measurements. From these data a model is built whose configuration is as close as possible to that of a living eye. Then the visual function of the model is calculated and checked for its conformity with the living eye. The second design approach starts with measurements of the optical performance of a living eye. Then the unknown parameters (asphericity of the cornea, distribution of the thicknesses of the individual layers of the crystalline lens, their curvatures and refractive indices, and sphericity of the layers) can be calculated by fitting the curve of the corresponding optical performance calculated from the model to the curve measured in vivo. Using this approach, we measured the axial spherical aberrations in 50 emmetropic volunteers (100 eyes), calculated the best fit to all the measurements, and used it as the average curve of axial spherical aberrations of an emmetropic eye. In this paper we present the results and calculations and discuss the validity of this approach.

Computers↗

A method to predetermine the correct photocoagulation dosage.

Relative absorbance in different locations on the retina has been studied by measuring the relative reflectance. Using this measurement it is possible to predetermine the correct dosage of light power in any new location on the retina by comparing the new reflectance with the reflectance in the test location. It is important to measure the reflectance with the aiming beam in its actual setting for application because the absorbance is affected by the angular orientation of the beam. A method is proposed for measuring, when needed, the relative concentration of blood and melanin at different points of the retina.

Humans↗

Time and location analysis of lesion formation in photocoagulation.

Fourteen eyes from seven owl monkeys were used for study of the time and location within the retinal layers of the formation of the white reactions produced by photocoagulation with green (530.9 nm), yellow (568.2 nm), or red (647.1 nm) krypton wavelengths. Locations on the retina with equivalent conditions of absorbance were chosen. The white reaction formed in the first 100 ms of application. The depth at which the most damage occurred depended on the wavelength used. The final shape of the lesion depended on the location (in depth) of the white reaction first formed and on the power of the laser beam. The cauterizing power of the krypton yellow was evident.

Animals↗